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ES8304996A1 - "procedimiento para la preparacion de nuevas cefalosporinas". - Google Patents

"procedimiento para la preparacion de nuevas cefalosporinas".

Info

Publication number
ES8304996A1
ES8304996A1 ES513020A ES513020A ES8304996A1 ES 8304996 A1 ES8304996 A1 ES 8304996A1 ES 513020 A ES513020 A ES 513020A ES 513020 A ES513020 A ES 513020A ES 8304996 A1 ES8304996 A1 ES 8304996A1
Authority
ES
Spain
Prior art keywords
group
general formula
procedure
preparation
ilo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513020A
Other languages
English (en)
Other versions
ES513020A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8304996A1 publication Critical patent/ES8304996A1/es
Publication of ES513020A0 publication Critical patent/ES513020A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE CEFALOSPORINAS, DE FORMULA GENERAL (I), EN LA QUE A SIGNIFICA UN GRUPO FENILO O 4-HIDROFENILO; D SIGNIFICA UN GRUPO 1-VINIL-TETRAZOL-5-ILO; R SIGNIFICA UN GRUPO DE FORMULA GENERAL: NHR , EN DONDE R SIGNIFICA UN GRUPO 3-PIRIDILO O 2-TIENILO; Y E SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO PROTECTOR DE CARBOXILO, Y SUS SALES FISIOLOGICAMENTE COMPATIBLES CON BASES ORGANICAS O INORGANICAS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN LA QUE A Y R TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON UN COMPUESTO DE FORMULA GENERAL: HET-S-M, EN LA QUE HET SIGNIFICA EL GRUPO 4H-5,6-DIOXO-1,2,4-TRIAZIN-3-ILO, Y M REPRESENTA UN ATOMO DE HIDROGENO O UN METAL ALCALINO. DE APLICACION EN LA PROFILAXIS Y EN LA QUIMIOTERAPIA DE INFECCIONES LOCALES.
ES513020A 1980-12-13 1982-06-11 "procedimiento para la preparacion de nuevas cefalosporinas". Granted ES513020A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803047082 DE3047082A1 (de) 1980-12-13 1980-12-13 Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8304996A1 true ES8304996A1 (es) 1983-03-16
ES513020A0 ES513020A0 (es) 1983-03-16

Family

ID=6119125

Family Applications (3)

Application Number Title Priority Date Filing Date
ES507829A Granted ES507829A0 (es) 1980-12-13 1981-12-10 Procedimiento para la preparacion de nuevas cefalosporinas .
ES513019A Granted ES513019A0 (es) 1980-12-13 1982-06-11 "procedimiento para la preparacion de nuevas cefalosporinas".
ES513020A Granted ES513020A0 (es) 1980-12-13 1982-06-11 "procedimiento para la preparacion de nuevas cefalosporinas".

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES507829A Granted ES507829A0 (es) 1980-12-13 1981-12-10 Procedimiento para la preparacion de nuevas cefalosporinas .
ES513019A Granted ES513019A0 (es) 1980-12-13 1982-06-11 "procedimiento para la preparacion de nuevas cefalosporinas".

Country Status (23)

Country Link
US (1) US4401667A (es)
EP (1) EP0054677B1 (es)
JP (1) JPS57123192A (es)
AR (1) AR229804A1 (es)
AT (1) ATE13536T1 (es)
AU (1) AU7814881A (es)
CA (1) CA1170652A (es)
CS (1) CS224637B2 (es)
DD (1) DD201905A5 (es)
DE (2) DE3047082A1 (es)
DK (1) DK542081A (es)
ES (3) ES507829A0 (es)
FI (1) FI813992A7 (es)
GB (1) GB2089346B (es)
GR (1) GR76948B (es)
HU (1) HU186448B (es)
IL (1) IL64427A (es)
NO (1) NO814240L (es)
NZ (1) NZ199129A (es)
PL (1) PL129917B1 (es)
PT (1) PT74117B (es)
SU (1) SU1075977A3 (es)
ZA (1) ZA818317B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
FR2816309B1 (fr) * 2000-11-09 2002-12-27 Bioprojet Soc Civ Procede de synthese de derives n-(mercaptoacyl)-amino-acides a partir d'acides acryliques alpha-substitues

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5344585A (en) * 1976-10-02 1978-04-21 Meiji Seika Kaisha Ltd Cephalosporin derivatives and their preparation
US4311699A (en) * 1979-03-12 1982-01-19 Haskell Theodore H Aminoacid derivatives of cephalosporin compounds
DE2924948A1 (de) * 1979-06-21 1981-01-22 Thomae Gmbh Dr K Neue cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2928344A1 (de) * 1979-07-13 1981-02-05 Thomae Gmbh Dr K Neue lactame, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3007685A1 (de) * 1980-02-29 1981-10-01 Dr. Karl Thomae Gmbh, 7950 Biberach Neue cephylosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0053276A3 (de) * 1980-12-02 1983-08-03 Dr. Karl Thomae GmbH Neue Cephalosporine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
PL129917B1 (en) 1984-06-30
AR229804A1 (es) 1983-11-30
AU7814881A (en) 1982-06-24
GB2089346B (en) 1984-08-15
ES8304995A1 (es) 1983-03-16
PT74117B (de) 1983-12-19
NO814240L (no) 1982-06-14
CA1170652A (en) 1984-07-10
NZ199129A (en) 1985-02-28
ES8302006A1 (es) 1983-01-01
ES507829A0 (es) 1983-01-01
DK542081A (da) 1982-06-14
EP0054677B1 (de) 1985-05-29
PL234192A1 (en) 1983-03-14
DE3170755D1 (en) 1985-07-04
PT74117A (de) 1982-01-01
HU186448B (en) 1985-07-29
US4401667A (en) 1983-08-30
GR76948B (es) 1984-09-04
DD201905A5 (de) 1983-08-17
IL64427A0 (en) 1982-03-31
ES513020A0 (es) 1983-03-16
SU1075977A3 (ru) 1984-02-23
FI813992L (fi) 1982-06-14
ATE13536T1 (de) 1985-06-15
JPS57123192A (en) 1982-07-31
CS224637B2 (en) 1984-01-16
ZA818317B (en) 1983-08-31
FI813992A7 (fi) 1982-06-14
EP0054677A2 (de) 1982-06-30
ES513019A0 (es) 1983-03-16
GB2089346A (en) 1982-06-23
DE3047082A1 (de) 1982-07-29
IL64427A (en) 1984-10-31
EP0054677A3 (en) 1983-07-06

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