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ES8304118A2 - IMPROVEMENTS IN THE PURPOSE OF MAIN PATENT N. 474.467 BY A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS. - Google Patents

IMPROVEMENTS IN THE PURPOSE OF MAIN PATENT N. 474.467 BY A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS.

Info

Publication number
ES8304118A2
ES8304118A2 ES478772A ES47877279A ES8304118A2 ES 8304118 A2 ES8304118 A2 ES 8304118A2 ES 478772 A ES478772 A ES 478772A ES 47877279 A ES47877279 A ES 47877279A ES 8304118 A2 ES8304118 A2 ES 8304118A2
Authority
ES
Spain
Prior art keywords
formula
quinazolins
procedure
preparation
main patent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES478772A
Other languages
Spanish (es)
Other versions
ES478772A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fermion Oy
Original Assignee
Fermion Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fermion Oy filed Critical Fermion Oy
Publication of ES478772A0 publication Critical patent/ES478772A0/en
Publication of ES8304118A2 publication Critical patent/ES8304118A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
    • C03C23/00—Other surface treatment of glass not in the form of fibres or filaments
    • C03C23/007—Other surface treatment of glass not in the form of fibres or filaments by thermal treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Process for the obtaining of formula quinazoline (I), where r is hydrogen or metoxyl; and r can be one of various types of radicals (certificate of addition of patent n 474.467). It consists of the ring closing reaction of a piperacin-1- (N-aril-N-cyan) -carboximidamide of formula (II), in which r and r have the same meaning as in formula (I). The reaction is carried out by heating at a temperature between 150 c and 220 c, in a solid solution. These compounds have pharmacological applications for their antihypertensive activity. (Machine-translation by Google Translate, not legally binding)
ES478772A 1977-10-25 1979-03-20 IMPROVEMENTS IN THE PURPOSE OF MAIN PATENT N. 474.467 BY A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS. Expired ES8304118A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI773168A FI57751C (en) 1977-10-25 1977-10-25 PROCEDURE FOR THE FRAMSTATION OF 6,7-DIMETOXY-ELLER 6,7,8-TRIMETOXY-4-AMINO-2- (4-SUBSTITUTES-PIPERAZIN-1-YL) -KINAZOLINE WITH BLODTRYCKSSAKANDE NETKAN

Publications (2)

Publication Number Publication Date
ES478772A0 ES478772A0 (en) 1983-03-01
ES8304118A2 true ES8304118A2 (en) 1983-03-01

Family

ID=8511169

Family Applications (2)

Application Number Title Priority Date Filing Date
ES474467A Expired ES474467A1 (en) 1977-10-25 1978-10-24 A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS.
ES478772A Expired ES8304118A2 (en) 1977-10-25 1979-03-20 IMPROVEMENTS IN THE PURPOSE OF MAIN PATENT N. 474.467 BY A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES474467A Expired ES474467A1 (en) 1977-10-25 1978-10-24 A PROCEDURE FOR THE PREPARATION OF QUINAZOLINS.

Country Status (7)

Country Link
JP (1) JPS55342A (en)
ES (2) ES474467A1 (en)
FI (1) FI57751C (en)
NL (1) NL7804135A (en)
PT (1) PT68691A (en)
YU (1) YU233278A (en)
ZA (1) ZA785322B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU70890A (en) * 1989-04-21 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for obtaining quinazoline derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process

Also Published As

Publication number Publication date
ES474467A1 (en) 1979-04-16
FI57751B (en) 1980-06-30
FI773168A7 (en) 1979-04-26
PT68691A (en) 1978-11-01
ES478772A0 (en) 1983-03-01
FI57751C (en) 1980-10-10
ZA785322B (en) 1979-09-26
NL7804135A (en) 1979-04-27
JPS55342A (en) 1980-01-05
YU233278A (en) 1983-01-21

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