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ES8205353A1 - Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico. - Google Patents

Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico.

Info

Publication number
ES8205353A1
ES8205353A1 ES498369A ES498369A ES8205353A1 ES 8205353 A1 ES8205353 A1 ES 8205353A1 ES 498369 A ES498369 A ES 498369A ES 498369 A ES498369 A ES 498369A ES 8205353 A1 ES8205353 A1 ES 8205353A1
Authority
ES
Spain
Prior art keywords
agent
per
weight
release
erosion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498369A
Other languages
English (en)
Other versions
ES498369A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/194,453 external-priority patent/US4308251A/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of ES498369A0 publication Critical patent/ES498369A0/es
Publication of ES8205353A1 publication Critical patent/ES8205353A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO DE FABRICACION DE COMPOSICIONES FARMACEUTICAS EN FORMA DE PASTILLA CONTENIENDO ACIDO ACETISALICILICO, EN LAS QUE SE OBTIENE UNA LIBERACION RETARDADA DEL AGENTE TERAPEUTICO. CONSISTENTE EN MEZCLAR INTIMAMENTE DE 90,9 A 98 POR 100 EN PESO DE ACIDO ACETILSALICILICO COMO AGENTE TERAPEUTICO CON 1,0 A 7,5 POR 100 EN PESO DE UN AGENTE ACTIVADOR DE LA EROSION. LA MEZCLA SE GRANULA UTILIZANDO UNA SOLUCION DE 0,8 A 1,6 POR 100 EN PESO DE UN AGENTE DE CONTROL DE LA LIBERACION EN UN DISOLVENTE ORGANICO. SECANDOSE A CONTINUACION LA MASA GRANULADA Y COMPRIMIENDOSE EN FORMA DE PASTILLAS. SE UTILIZA PREFERENTEMENTE ACETATO-FTALATO DE CELULOSA COMO AGENTE DE CONTROL DE LA LIBERACION Y ALMIDON DE MAIZ COMO AGENTE ACTIVADOR DE LA EROSION.
ES498369A 1980-01-11 1981-01-08 Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico. Expired ES8205353A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11143080A 1980-01-11 1980-01-11
US06/194,453 US4308251A (en) 1980-01-11 1980-10-17 Controlled release formulations of orally-active medicaments

Publications (2)

Publication Number Publication Date
ES498369A0 ES498369A0 (es) 1982-06-01
ES8205353A1 true ES8205353A1 (es) 1982-06-01

Family

ID=26808896

Family Applications (2)

Application Number Title Priority Date Filing Date
ES498369A Expired ES8205353A1 (es) 1980-01-11 1981-01-08 Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico.
ES509179A Expired ES8301629A1 (es) 1980-01-11 1982-01-29 "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES509179A Expired ES8301629A1 (es) 1980-01-11 1982-01-29 "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen".

Country Status (22)

Country Link
JP (1) JPS56103110A (es)
AT (1) AT374681B (es)
AU (1) AU542824B2 (es)
BE (1) BE886998A (es)
CA (1) CA1140466A (es)
CH (1) CH646604A5 (es)
DE (1) DE3100191A1 (es)
DK (1) DK6181A (es)
ES (2) ES8205353A1 (es)
FI (1) FI76927C (es)
FR (1) FR2473308B1 (es)
GB (1) GB2067072B (es)
GR (1) GR73843B (es)
IE (1) IE50806B1 (es)
IN (1) IN151913B (es)
IT (1) IT1221041B (es)
LU (1) LU83052A1 (es)
NL (1) NL8100037A (es)
NO (1) NO156153C (es)
NZ (1) NZ195933A (es)
SE (1) SE447450B (es)
ZA (1) ZA81136B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496082A (en) * 1947-05-24 1950-01-31 Ashenfelter William Scaffold structure
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPS59227817A (ja) * 1983-06-07 1984-12-21 Toyo Jozo Co Ltd 持続性経口用ブレデニン製剤
JPH0662404B2 (ja) * 1983-06-14 1994-08-17 シンテックス・ファーマシユーテイカルズ・インターナシヨナル・リミテツド 制御放出性ナプロキセンおよびナプロキセンナトリウム錠
ZA836031B (en) * 1983-08-16 1985-02-27 Verex Lab Constant release rate solid dosage theophylline formulation
ZA836030B (en) * 1983-08-16 1985-02-27 Verex Lab Constant order release solid dosage indomethacin formulation and method of treating arthritis and other inflammatory conditions
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
US5385738A (en) * 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
DE3486029T2 (de) * 1983-10-14 1993-05-13 Sumitomo Pharma Ifn-praeparat mit verzoegerter abgabe fuer parentale verabreichung.
ES2054613T3 (es) * 1985-12-27 1994-08-16 Sumitomo Pharma Un metodo para preparar una formulacion de liberacion mantenida.
GB8601204D0 (en) * 1986-01-18 1986-02-19 Boots Co Plc Therapeutic agents
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
CA1316110C (en) * 1987-02-27 1993-04-13 Peter Lloyd Oren Sustained release matrix formulations
WO1997002019A1 (en) 1995-06-30 1997-01-23 Baylor University Polyester/carboxylic acid composite materials

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2953497A (en) * 1953-06-03 1960-09-20 Howard A Press Therapeutic tablets
BE604564A (es) * 1960-06-06
US3577514A (en) * 1968-06-10 1971-05-04 Pfizer Sustained release pharmaceutical tablets
US3773920A (en) * 1971-07-14 1973-11-20 Nikken Chemicals Co Ltd Sustained release medicinal composition
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
GB1500300A (en) * 1975-01-06 1978-02-08 Ciba Geigy Ag Pharmaceutical preparation for the treatment of circulatory disorders
JPS5411226A (en) * 1977-06-24 1979-01-27 Shin Etsu Chem Co Ltd Disintegratable granule

Also Published As

Publication number Publication date
NO810062L (no) 1981-07-13
DE3100191C2 (es) 1988-09-01
IN151913B (es) 1983-09-03
GB2067072A (en) 1981-07-22
ES498369A0 (es) 1982-06-01
GB2067072B (en) 1983-08-10
LU83052A1 (fr) 1982-09-10
FI76927C (fi) 1989-01-10
NO156153B (no) 1987-04-27
NO156153C (no) 1987-08-05
GR73843B (es) 1984-05-07
BE886998A (fr) 1981-07-08
FI76927B (fi) 1988-09-30
IE810036L (en) 1981-07-11
FI810056L (fi) 1981-07-12
CA1140466A (en) 1983-02-01
ATA5481A (de) 1983-10-15
AU6597681A (en) 1981-07-16
ES509179A0 (es) 1982-12-16
FR2473308B1 (fr) 1985-07-19
AT374681B (de) 1984-05-25
NL8100037A (nl) 1981-08-03
IT1221041B (it) 1990-06-21
SE8100104L (sv) 1981-07-12
NZ195933A (en) 1982-11-23
IE50806B1 (en) 1986-07-23
FR2473308A1 (fr) 1981-07-17
CH646604A5 (fr) 1984-12-14
DE3100191A1 (de) 1981-12-10
SE447450B (sv) 1986-11-17
DK6181A (da) 1981-07-12
AU542824B2 (en) 1985-03-14
JPS56103110A (en) 1981-08-18
ES8301629A1 (es) 1982-12-16
IT8147537A0 (it) 1981-01-09
ZA81136B (en) 1982-01-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201