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ES8205220A1 - Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal - Google Patents

Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal

Info

Publication number
ES8205220A1
ES8205220A1 ES504585A ES504585A ES8205220A1 ES 8205220 A1 ES8205220 A1 ES 8205220A1 ES 504585 A ES504585 A ES 504585A ES 504585 A ES504585 A ES 504585A ES 8205220 A1 ES8205220 A1 ES 8205220A1
Authority
ES
Spain
Prior art keywords
derivatives
antiprotozoal
preparation
pharmaceutical compositions
novel antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504585A
Other languages
English (en)
Other versions
ES504585A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FARMATIS Srl
Original Assignee
FARMATIS Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FARMATIS Srl filed Critical FARMATIS Srl
Publication of ES8205220A1 publication Critical patent/ES8205220A1/es
Publication of ES504585A0 publication Critical patent/ES504585A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ESTERES DEL ACIDO SUCCIONICO, DE FORMULA (I), EN LA QUE R ES ALQUILO C1-6 Y R1 ES HIDROGENO O METOXILO, COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES PROTOZOARIAS E INFECCIONES BACTERIALES. CONSISTE EN LA REACCION DE 2-AMINO-4,2-(1-ALQUILO INFERIOR-5-NITRO-2-IMIDAZOLIL)-VINIL PIRIMIDINA CON UN LIGERO EXCESO DE ANHIDRIDO SUCCINICO, POR CALENTAMIENTO A EFLUJO, SEGUIDA DE LA REACCION DEL DERIVADO (-SUCCINILO FORMADO CON O-TERC-BUTILFENOL, OPCIONALMENTE SUSTITUIDO EN PARA POR ALCOXI INFERIOR, EN PRESENCIA DE ACIDO SULFURICO CONCENTRADO.
ES504585A 1980-08-07 1981-08-06 Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal Granted ES504585A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8025832A GB2081706B (en) 1980-08-07 1980-08-07 Antibacterial and antiprotozoal derivatives

Publications (2)

Publication Number Publication Date
ES8205220A1 true ES8205220A1 (es) 1982-06-01
ES504585A0 ES504585A0 (es) 1982-06-01

Family

ID=10515308

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504585A Granted ES504585A0 (es) 1980-08-07 1981-08-06 Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal

Country Status (6)

Country Link
EP (1) EP0045990A1 (es)
BE (1) BE889875A (es)
ES (1) ES504585A0 (es)
FR (1) FR2488256A1 (es)
GB (1) GB2081706B (es)
IT (1) IT1138132B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106986789B (zh) * 2016-01-20 2019-07-16 中国人民解放军军事医学科学院生物医学分析中心 对苯二酚类化合物及其制备方法与在抗肿瘤或免疫调节中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3969520A (en) * 1973-05-25 1976-07-13 Istituto Chemioterapico Italiano S.P.A. 2-Amino-4[2-(1-lower alkyl-5-nitro-2-imidiazolyl)vinyl]pyrimidines for treating protozoal and bacterial infections

Also Published As

Publication number Publication date
IT8123340A0 (it) 1981-08-03
FR2488256B1 (es) 1983-11-18
IT1138132B (it) 1986-09-17
BE889875A (fr) 1981-12-01
EP0045990A1 (en) 1982-02-17
GB2081706B (en) 1984-03-07
ES504585A0 (es) 1982-06-01
GB2081706A (en) 1982-02-24
FR2488256A1 (fr) 1982-02-12

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