ES8202011A1 - Un procedimiento para la preparacion de derivados de campto-tecina - Google Patents
Un procedimiento para la preparacion de derivados de campto-tecinaInfo
- Publication number
- ES8202011A1 ES8202011A1 ES499986A ES499986A ES8202011A1 ES 8202011 A1 ES8202011 A1 ES 8202011A1 ES 499986 A ES499986 A ES 499986A ES 499986 A ES499986 A ES 499986A ES 8202011 A1 ES8202011 A1 ES 8202011A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- derivatives
- procedure
- preparation
- camptotechine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE CAMPTOETECINA DE FORMULA GENERAL (I), DONDE X'''''' REPRESENTA UN GRUPO ALQUILO, ARALQUILO O -COOR4, DONDE R4 ES H O UN GRUPO ALQUILO INFERIOR, ASI COMO SUS SALES DE METALES ALCALINOS SOLUBLES EN AGUA. CONSISTE EN SOMETER A LA CAMPTOTECINA A UNA REACCION RADICALICA CON UN COMPUESTO ORGANICO DE FORMULA (II), DONDE Q REPRESENTA UN GRUPO -CH2OH, -COOH, -CHO O -COX'''', Y X'''' REPRESENTA UN GRUPO ALQUILO O ARALQUILO, CON LA AYUDA DE UN ACIDO SULFURICO Y UN PEROXIDO EN MEDIO ACUOSO, EN PRESENCIA DE UN ION METALICO DE TRANSICION, Y OPCIONALMENTE OXIDAR EL DERIVADO DE 7-X''''-CAMPTOTECINA RESULTANTE, DONDE X'''' REPRESENTA UN GRUPO ALQUILO, A UNA 7-X''''''-CAMPTOTECINA, DONDE X'''''' REPRESENTA UN GRUPO CARBOXI, Y DESPUES, ESTERIFICAR EL GRUPO CARBOXI.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8641179A JPS5612392A (en) | 1979-07-10 | 1979-07-10 | Novel camptothecin derivative and its preparation |
| JP8641079A JPS5612391A (en) | 1979-07-10 | 1979-07-10 | Novel camptothecin derivative and its preparaion |
| JP8641279A JPS5612393A (en) | 1979-07-10 | 1979-07-10 | Novel camptothecin derivative |
| JP8641379A JPS5612394A (en) | 1979-07-10 | 1979-07-10 | Novel camptothecin derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES499986A0 ES499986A0 (es) | 1982-01-01 |
| ES8202011A1 true ES8202011A1 (es) | 1982-01-01 |
Family
ID=27467257
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493287A Granted ES493287A0 (es) | 1979-07-10 | 1980-07-10 | Un procedimiento para la preparacion de derivados de campto tecina. |
| ES499987A Granted ES499987A0 (es) | 1979-07-10 | 1981-03-02 | Un procedimiento para la preparacion de derivados de campto-tecina |
| ES499986A Expired ES8202011A1 (es) | 1979-07-10 | 1981-03-02 | Un procedimiento para la preparacion de derivados de campto-tecina |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493287A Granted ES493287A0 (es) | 1979-07-10 | 1980-07-10 | Un procedimiento para la preparacion de derivados de campto tecina. |
| ES499987A Granted ES499987A0 (es) | 1979-07-10 | 1981-03-02 | Un procedimiento para la preparacion de derivados de campto-tecina |
Country Status (1)
| Country | Link |
|---|---|
| ES (3) | ES493287A0 (es) |
-
1980
- 1980-07-10 ES ES493287A patent/ES493287A0/es active Granted
-
1981
- 1981-03-02 ES ES499987A patent/ES499987A0/es active Granted
- 1981-03-02 ES ES499986A patent/ES8202011A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES8202012A1 (es) | 1982-01-01 |
| ES499987A0 (es) | 1982-01-01 |
| ES8105735A1 (es) | 1981-06-16 |
| ES499986A0 (es) | 1982-01-01 |
| ES493287A0 (es) | 1981-06-16 |
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