[go: up one dir, main page]

ES8200770A1 - Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos. - Google Patents

Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos.

Info

Publication number
ES8200770A1
ES8200770A1 ES491029A ES491029A ES8200770A1 ES 8200770 A1 ES8200770 A1 ES 8200770A1 ES 491029 A ES491029 A ES 491029A ES 491029 A ES491029 A ES 491029A ES 8200770 A1 ES8200770 A1 ES 8200770A1
Authority
ES
Spain
Prior art keywords
reagent
latex
preparation
approximately
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491029A
Other languages
English (en)
Other versions
ES491029A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of ES8200770A1 publication Critical patent/ES8200770A1/es
Publication of ES491029A0 publication Critical patent/ES491029A0/es
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Materials For Medical Uses (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE UN REACTIVO DE LATEX PARA LA DETECCION Y LA DETERMINACION DE PROTEINAS Y PEPTIDOS CLONICAMENTE RELEVANTES CON METODOS NEFELOMETRICOS O TUBIRDIMETRICOS. SE HACE REACCIONAR UNA SUSPENSION DE PARTICULAS DE LATEX DE APROXIMADAMENTE 0,1 HASTA 0,35 UM DE DIAMETRO CON UNA CANTIDAD EN PESO MULTIPLICADA POR UN FACTOR DE APROXIMADAMENTE 0,6 HASTA 3,3 DE UN ANTIGENO O ANTICUERPO. SE MEZCLA ESTA SUSPENSION CON OTRA DE PARTICULAS DE LATEX TAMBIEN, SIENDO EL TAMAÑO DE LAS PARTICULAS DE 0,5 A 2 UM, QUE ESTAN CARGADAS CON UNA CANTIDAD MULTIPLICADA POR UN FACTOR DE ALREDEDOR DE 0,1 DEL MISMO ANTIGENO O ENTICUERPO EN LA PROPORCION DE APROXIMADAMENTE 4 : 1 HASTA 1 : 2. EVENTUALMENTE SE TRATA CON ULTRASONIDOS Y SE DEJA REPOSAR.
ES491029A 1979-05-07 1980-04-30 Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos. Granted ES491029A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792918342 DE2918342A1 (de) 1979-05-07 1979-05-07 Latex-reagenz

Publications (2)

Publication Number Publication Date
ES8200770A1 true ES8200770A1 (es) 1981-11-01
ES491029A0 ES491029A0 (es) 1981-11-01

Family

ID=6070116

Family Applications (2)

Application Number Title Priority Date Filing Date
ES491029A Granted ES491029A0 (es) 1979-05-07 1980-04-30 Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos.
ES498270A Expired ES8201315A1 (es) 1979-05-07 1980-12-31 Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES498270A Expired ES8201315A1 (es) 1979-05-07 1980-12-31 Procedimiento para la deteccion y la determinacion de un an-tigeno o anticuerpo

Country Status (8)

Country Link
US (1) US4305925A (es)
EP (1) EP0019741B1 (es)
JP (1) JPS55151264A (es)
AT (1) ATE16130T1 (es)
AU (1) AU527485B2 (es)
DE (2) DE2918342A1 (es)
DK (1) DK153589C (es)
ES (2) ES491029A0 (es)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU543007B2 (en) * 1980-04-15 1985-03-28 Technicon Instruments Corportion Agglutination immunoassay
JPS58500874A (ja) * 1981-06-02 1983-05-26 エレクトロ−ヌ−　クレオニツクス、インコ−ポレ−テツド 免疫沈殿分析
EP0070527B1 (en) * 1981-07-17 1985-06-19 Toray Industries, Inc. Method of assaying biologically active substances and labelling agents therefor
US4792527A (en) * 1981-07-17 1988-12-20 Toray Industries, Inc. Method of assaying biologically active substances and labelling agents therefor
DE3145082A1 (de) * 1981-11-13 1983-05-19 Behringwerke Ag, 3550 Marburg "ein latex, biologisch aktive latexkonjugate und verfahren zu ihrer herstellung"
US4543339A (en) * 1982-03-16 1985-09-24 Oneill Christopher Early pregnancy detection by detecting enhanced blood platelet activation
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
JPS58209994A (ja) * 1982-05-10 1983-12-07 Fujirebio Inc 活性蛋白等固定化物を用いた抗原の測定方法
US4459361A (en) * 1982-06-04 1984-07-10 Angenics, Inc. Ligand assay with one or two particulate reagents and filter
GB2123146B (en) * 1982-06-28 1985-09-25 Abbott Lab Dual parameter flow immunoassays
DE3366740D1 (en) * 1982-08-06 1986-11-13 Int Inst Cellular Molecul Path Particle agglutination assay of antigens
FR2531718B1 (fr) * 1982-08-16 1986-11-21 Sanofi Sa Reactif permettant un dosage de tres haute sensibilite de l'antigene caracteristique du virus de l'hepatite b dans les liquides biologiques humains
US4590169A (en) * 1983-11-18 1986-05-20 Beckman Instruments, Inc. Direct particle agglutination immunoassays avoiding false negatives at high antigen concentrations
US4595661A (en) * 1983-11-18 1986-06-17 Beckman Instruments, Inc. Immunoassays and kits for use therein which include low affinity antibodies for reducing the hook effect
AU4158785A (en) * 1984-03-26 1985-11-01 International Health Services A method of determining the clotting time of blood and particulate reagents therefor
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
JPH0650314B2 (ja) * 1984-09-08 1994-06-29 オリンパス光学工業株式会社 免疫反応測定装置
US4762413A (en) * 1984-09-07 1988-08-09 Olympus Optical Co., Ltd. Method and apparatus for measuring immunological reaction with the aid of fluctuation in intensity of scattered light
EP0189389B1 (fr) * 1985-01-24 1989-04-05 Institut International De Pathologie Cellulaire Et Moleculaire Procédé de dosage immunologique d'anticorps de diverses classes dans un échantillon liquide
DE3507574A1 (de) * 1985-03-04 1986-09-04 Gödecke AG, 1000 Berlin Zweistufiger agglutinationsschnelltest zum kombinierten nachweis "seropositiver" und "seronegativer" rheumafaktoren
GB8526355D0 (en) * 1985-10-25 1985-11-27 Alta Diagnostic Machines Ltd Determination of antibody content of blood
US5770459A (en) * 1986-04-30 1998-06-23 Igen International, Inc. Methods and apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence detection
GB8621495D0 (en) * 1986-09-05 1986-10-15 Acade Diagnostic Systems Sa Nv Assay
JP2588174B2 (ja) * 1986-09-08 1997-03-05 三菱化学株式会社 抗原−抗体反応の測定法
US6881589B1 (en) 1987-04-30 2005-04-19 Bioveris Corporation Electrochemiluminescent localizable complexes for assay compositions
US5935779A (en) * 1988-11-03 1999-08-10 Igen International Inc. Methods for improved particle electrochemiluminescence assay
US5779976A (en) * 1988-11-03 1998-07-14 Igen International, Inc. Apparatus for improved luminescence assays
US5746974A (en) * 1988-11-03 1998-05-05 Igen International, Inc. Apparatus for improved luminescence assays using particle concentration, electrochemical generation of chemiluminescence and chemiluminescence detection
US5705402A (en) * 1988-11-03 1998-01-06 Igen International, Inc. Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets
US5962218A (en) * 1988-11-03 1999-10-05 Igen International Inc. Methods and apparatus for improved luminescence assays
DE69027382T2 (de) * 1989-08-23 1997-01-09 Canon Kk Methode zur Messung eines immunologisch aktiven Materials und dazu geeignete Vorrichtung
DE69017471D1 (de) * 1990-02-22 1995-04-06 Univ Mcgill Feststoff-phase-interferometrisches immunotestsystem.
US5250186A (en) * 1990-10-23 1993-10-05 Cetus Corporation HPLC light scattering detector for biopolymers
US5269937A (en) * 1990-10-23 1993-12-14 Cetus Corporation HPLC light scattering detector for biopolymers
ZA92803B (en) 1991-02-06 1992-11-25 Igen Inc Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets
US5290707A (en) * 1991-11-25 1994-03-01 The United States Of America As Represented By The Secretary Of The Army Method for detection of microorganisms
DE4202924A1 (de) * 1992-02-01 1993-08-05 Behringwerke Ag Verfahren zur bestimmung von rheumafaktoren und mittel zur durchfuehrung des verfahrens
US6200820B1 (en) 1992-12-22 2001-03-13 Sienna Biotech, Inc. Light scatter-based immunoassay
TW239881B (es) * 1992-12-22 1995-02-01 Sienna Biotech Inc
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6019968A (en) * 1995-04-14 2000-02-01 Inhale Therapeutic Systems, Inc. Dispersible antibody compositions and methods for their preparation and use
US5628432A (en) * 1996-04-03 1997-05-13 Mosley; Julius Personal cooling system
JP3652029B2 (ja) * 1996-10-16 2005-05-25 積水化学工業株式会社 高感度免疫測定法
US5858648A (en) * 1996-11-04 1999-01-12 Sienna Biotech, Inc. Assays using reference microparticles
CA2412994A1 (en) * 2000-06-30 2002-12-27 Kyowa Medex Co., Ltd. Insoluble carrier particle nephelometric immunoassay reagent
US20040091940A1 (en) * 2001-03-30 2004-05-13 Tokio Sawai Reagent and method for immunoanalysis of elastase 1 and method of detecting pancreatic disease
US7338813B2 (en) * 2001-07-02 2008-03-04 Sekisui Chemical Co., Ltd. Carrier particle latex for assay reagent and assay reagent
AU2005246289A1 (en) * 2004-05-15 2005-12-01 Genentech, Inc. Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
JP4331073B2 (ja) * 2004-08-31 2009-09-16 デンカ生研株式会社 抗原の測定方法及びそのための試薬
ES2675044T3 (es) * 2005-06-03 2018-07-06 Board Of Regents Of The University Of Texas System Electroquímica y quimioluminiscencia electrogenerada con un único electrodo faradaico
CN101680891A (zh) * 2007-11-21 2010-03-24 爱科来株式会社 测定试剂、使用其的免疫比浊法和待测物分析用具
CN105181962B (zh) * 2015-09-02 2016-09-14 郁东 一种类风湿因子检测试剂
WO2018181549A1 (ja) 2017-03-28 2018-10-04 デンカ株式会社 膜担体、並びにそれを用いた液体試料検査キット及びその製造方法
DE102021111494A1 (de) 2021-05-04 2022-11-10 Atral-Secal Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen
DE102021126818A1 (de) 2021-10-15 2023-04-20 Atral-Secal Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen
CN114935655B (zh) * 2022-06-16 2024-02-20 安徽农业大学 一种猪il-17胶乳增强免疫比浊法检测试剂盒及其制备使用方法
CN115754312A (zh) * 2022-10-12 2023-03-07 湖南菲科生物技术有限公司 氧化型低密度脂蛋白检测试剂盒及其制备方法
DE102022132609A1 (de) 2022-12-08 2024-06-13 Hager Safety Deutschland Gmbh Nachweisgerät sowie ein Nachweisverfahren für in Luft enthaltene pathogene Substanzen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1179435A (en) * 1966-06-17 1970-01-28 Ortho Pharma Corp Stable Reagent for the Detection of Rheumatoid Arthritis
US3925018A (en) * 1973-06-08 1975-12-09 Technicon Instr Method and apparatus for quantitative analysis utilizing particulate reagent material
US4035316A (en) * 1975-11-24 1977-07-12 California Institute Of Technology Cell specific, variable density, polymer microspheres
US4143203A (en) * 1976-03-19 1979-03-06 Amicon Corporation Particulate support material
IT1087285B (it) * 1976-11-10 1985-06-04 Hoffmann La Roche Procedimento di determinazione immunologico
GB1590525A (en) * 1976-12-10 1981-06-03 Technicon Instr Biological analysis
CH628738A5 (de) * 1977-08-03 1982-03-15 Hoffmann La Roche Immunologisches diagnose-reagenz.
US4191739A (en) * 1977-10-17 1980-03-04 General Electric Company Antigen-antibody reaction assay employing particle aggregation and resistive pulse analysis

Also Published As

Publication number Publication date
JPS6314783B2 (es) 1988-04-01
AU527485B2 (en) 1983-03-03
ES498270A0 (es) 1981-12-01
AU5813080A (en) 1980-11-13
EP0019741A1 (de) 1980-12-10
ES8201315A1 (es) 1981-12-01
DK153589B (da) 1988-07-25
DK153589C (da) 1988-12-12
DE3071183D1 (en) 1985-11-21
JPS55151264A (en) 1980-11-25
US4305925A (en) 1981-12-15
DE2918342A1 (de) 1980-11-20
ATE16130T1 (de) 1985-11-15
EP0019741B1 (de) 1985-10-16
DK198380A (da) 1980-11-08
ES491029A0 (es) 1981-11-01

Similar Documents

Publication Publication Date Title
ES8200770A1 (es) Procedimiento de preparacion de un reactivo de latex para la deteccion y la determinacion de anticuerpos o antigenos.
JPS55143440A (en) Magnetic classificaton of cells and fine balls used therefor
IE48400B1 (en) Process for immunologic determination tests
ES2035357T3 (es) Procedimiento para demostrar la existencia de antigenos y/o anticuerpos, asi como equipo de ensayo para realizar el procedimiento
DE3265768D1 (en) A method and a kit for the assay of antibodies to soluble antigens
Flick Use of formalin-treated red cells for the study of influenza A virus hemagglutinating activity
Simpson et al. Species identification of animal cell strains by immunofluorescence
Haughton Transplantation antigen of mice: cellular localization of antigen determined by the H-2 locus
ES8404515A1 (es) Procedimiento de aglutinacion con latex para la deteccion o la determinacion de un participante en una reaccion inmunologica.
Nelson Jr et al. On the Mechanism of Immune-Adherence: II. Analogy to Mixed Aggregation of Sensitized Antigens in the Presence of Complement; Immune-Adherence with Animal Platelets
Mori et al. A method for specific detection of autoantibodies to the zona pellucida in infertile women
Reyes et al. DNA-binding property of Sm nuclear antigen.
AZOURY et al. Intradermal tests and antinuclear factors in systemic lupus erythematosus: A comparative study
Vacquier et al. The effect of soluble egg jelly on the fertilizability of acid‐dejellied sea urchin eggs
JPS5530652A (en) Latex sensitive to antibody of human beta2-microglobulin for quantitizing human beta2-microglobulin and its composite
Habeeb et al. Preparation of human immunoglobulin by ammonium sulfate precipitation
Mattsson Increase in the number of splenic plaque forming cells with length of gestation in untreated pregnant mice
Magrath et al. Induction of complement receptor expression in cell lines derived from human undifferentiated lymphomas. II. Characterization of the induced complement receptors and demonstration of the simultaneous induction of EBV receptor.
Tjokronegoro et al. Degradation of immunoglobulins by secretions of human reproductive tracts
SE8803208D0 (sv) In vitro immunisering av lymfocytinnehallande cellpopulationer och materialsats derfor
Markowitz Interactions of anti-glomerular basement membrane antisera
ES405388A1 (es) Procedimiento de ensayo para determinar la presencia de an-tigeno de australia de una muestra de sangre.
PT81050B (pt) Anticorpo monoclonal anti-urocinase e processo para a preparacao de composicoes de materia de teste biologicos que o utilizam
McLean et al. A technique for the specific staining of macromolecules and viruses with ferritin-antibody conjugates
ES2054195T3 (es) Ensayo inmunologico de aglutinacion indirecta y aparato para el mismo.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001