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ES8106834A1 - Un metodo de producir un antisuero que tiene una mejor cua- lidad aglutinante - Google Patents

Un metodo de producir un antisuero que tiene una mejor cua- lidad aglutinante

Info

Publication number
ES8106834A1
ES8106834A1 ES495177A ES495177A ES8106834A1 ES 8106834 A1 ES8106834 A1 ES 8106834A1 ES 495177 A ES495177 A ES 495177A ES 495177 A ES495177 A ES 495177A ES 8106834 A1 ES8106834 A1 ES 8106834A1
Authority
ES
Spain
Prior art keywords
igg
agglutination
serum
cells
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES495177A
Other languages
English (en)
Other versions
ES495177A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gamma Biologicals Inc
Original Assignee
Gamma Biologicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gamma Biologicals Inc filed Critical Gamma Biologicals Inc
Publication of ES8106834A1 publication Critical patent/ES8106834A1/es
Publication of ES495177A0 publication Critical patent/ES495177A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

METODO PARA PRODUCIR ANTISUERO CON BUENAS CUALIDADES AGLUTINANTES. COMPRENDE LAS SIGUIENTES ETAPAS: PRIMERA, SEPARAR LA FRACCION DE INMUNOGLOBULINA IGM DE UN SUERO QUE CONTIENE INMUNOGLOBULINA IGG EN DISOLUCION; SEGUNDA, SOMETER LA DISOLUCION RESTANTE, QUE CONTIENE IGG, A UNAS CONDICIONES REDUCTORAS SUAVES Y SUFICIENTES PARA ESCINDIR LOS ENLACES DISULFURO QUE UNEN LAS CADENAS DE POLIPEPTIDOS DE LA MOLECULA DE IGG, SIN REDUCIR DE MODO IMPORTANTE OTRAS PORCIONES DE LA MOLECULA; TERCERA, FIJAR LA MOLECULA ASI REDUCIDA PARA EVITAR SUSTANCIALMENTE LA REOXIDACION Y LA FORMACION DE ENLACES DISULFURO; CUARTA, SEPARAR CUALQUIER AGENTE REDUCTOR Y FIJADOR DE LA DISOLUCION, Y POR ULTIMO, COMBINAR LA DISOLUCION CON LA FRACCION DE IGM SEPARADA EN LA PRIMERA ETAPA. DE USO EN LA PREPARACION DE SUEROS ANTICUERPO CAPACES DE AGLUTINAR DIRECTAMENTE, EN SUSPENSION SALINA, ERITROCITOS HUMANOS QUE LLEVAN EL ANTIGENO DEL GRUPO SANGUINEO APROPIADO.
ES495177A 1979-12-26 1980-09-19 Un metodo de producir un antisuero que tiene una mejor cua- lidad aglutinante Granted ES495177A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10749979A 1979-12-26 1979-12-26

Publications (2)

Publication Number Publication Date
ES8106834A1 true ES8106834A1 (es) 1981-09-01
ES495177A0 ES495177A0 (es) 1981-09-01

Family

ID=22316939

Family Applications (1)

Application Number Title Priority Date Filing Date
ES495177A Granted ES495177A0 (es) 1979-12-26 1980-09-19 Un metodo de producir un antisuero que tiene una mejor cua- lidad aglutinante

Country Status (7)

Country Link
JP (1) JPS5694267A (es)
AU (1) AU6071780A (es)
DE (1) DE3028977A1 (es)
ES (1) ES495177A0 (es)
GB (1) GB2066259B (es)
IT (1) IT8049473A0 (es)
NZ (1) NZ194363A (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61213673A (ja) * 1985-03-19 1986-09-22 Morinaga Milk Ind Co Ltd 免疫学的測定試薬の製造法
CA2008213A1 (en) * 1989-02-21 1990-08-21 David A. Hilborn Method of fragmenting certain monoclonal antibodies
GB8919761D0 (en) * 1989-09-01 1989-10-18 Central Blood Lab Authority Chemical compounds
EP1465720A4 (en) * 2001-12-19 2010-05-12 Biogen Idec Inc METHODS FOR DETECTING HALF ANTIBODIES BY IMPLEMENTING GEL ELECTROPHORESIS ON INTEGRATED CIRCUITS
WO2005052567A1 (en) * 2003-11-24 2005-06-09 Biogen Idec Ma Inc. Methods for detecting half-antibodies using chip-based gel electrophoresis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5417721B2 (es) * 1974-03-08 1979-07-02
ZA804197B (en) * 1979-07-13 1982-02-24 Ortho Diagnostics Anti-d test and reagent

Also Published As

Publication number Publication date
AU6071780A (en) 1981-07-02
NZ194363A (en) 1982-12-21
GB2066259A (en) 1981-07-08
JPS5694267A (en) 1981-07-30
IT8049473A0 (it) 1980-08-12
DE3028977A1 (de) 1981-07-02
GB2066259B (en) 1983-05-25
ES495177A0 (es) 1981-09-01

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