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ES8106136A1 - Procedimiento para la preparacion de bis-(n-(3,5-bis-(hidro-xialcohilaminocarbonil)-2,4,6-triyodofenil)-n-(a-hidroxia- cil)-amino)-alcanos - Google Patents

Procedimiento para la preparacion de bis-(n-(3,5-bis-(hidro-xialcohilaminocarbonil)-2,4,6-triyodofenil)-n-(a-hidroxia- cil)-amino)-alcanos

Info

Publication number
ES8106136A1
ES8106136A1 ES494077A ES494077A ES8106136A1 ES 8106136 A1 ES8106136 A1 ES 8106136A1 ES 494077 A ES494077 A ES 494077A ES 494077 A ES494077 A ES 494077A ES 8106136 A1 ES8106136 A1 ES 8106136A1
Authority
ES
Spain
Prior art keywords
bis
amino
procedure
preparation
xialcohilaminocarbonil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494077A
Other languages
English (en)
Other versions
ES494077A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco SpA
Original Assignee
Bracco SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco SpA filed Critical Bracco SpA
Publication of ES494077A0 publication Critical patent/ES494077A0/es
Publication of ES8106136A1 publication Critical patent/ES8106136A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE BIS-[N-{3,5-BIS-(HIDROXIALCOHILAMINOCARBONIL)-2,4,6-TRIYODOFENIL}-N-(AL FA-HIDROXIACIL)-AMINO]-ALCANOS. EL PROCESO CONSISTE EN SOMETER A ALCOHILACION EN MEDIO ALCALINO EN EL ATOMO DE NITROGENO AROMATICO A UNA BIS(DIHIDROXIPROPILAMIDA) DE ACIDO 5-ALFA-HIDROXIACILAMINO-2,4,6-TRIYODO-ISOFTALICO DE FORMULA (I) POR REACCION CON AGENTES ALCOHILANTES. ESTOS COMPUESTOS SON APROPIADOS PARA LA VASOGRAFIA, LA UROGRAFIA, LA BRONCOGRAFIA, COMO AGENTES DE CONSTRASTE DE RAYOS X NO IONICOS. L
ES494077A 1979-08-09 1980-08-08 Procedimiento para la preparacion de bis-(n-(3,5-bis-(hidro-xialcohilaminocarbonil)-2,4,6-triyodofenil)-n-(a-hidroxia- cil)-amino)-alcanos Expired ES8106136A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT7925027A IT1207226B (it) 1979-08-09 1979-08-09 Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.

Publications (2)

Publication Number Publication Date
ES494077A0 ES494077A0 (es) 1981-08-01
ES8106136A1 true ES8106136A1 (es) 1981-08-01

Family

ID=11215467

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494077A Expired ES8106136A1 (es) 1979-08-09 1980-08-08 Procedimiento para la preparacion de bis-(n-(3,5-bis-(hidro-xialcohilaminocarbonil)-2,4,6-triyodofenil)-n-(a-hidroxia- cil)-amino)-alcanos

Country Status (18)

Country Link
US (1) US4348377A (es)
EP (1) EP0023992B1 (es)
JP (1) JPS5935913B2 (es)
AR (1) AR223890A1 (es)
AT (1) ATE1234T1 (es)
AU (1) AU537446B2 (es)
CA (1) CA1123009A (es)
DE (1) DE3060592D1 (es)
DK (1) DK157190C (es)
ES (1) ES8106136A1 (es)
FI (1) FI73200C (es)
IE (1) IE50148B1 (es)
IT (1) IT1207226B (es)
NO (1) NO149171C (es)
PL (1) PL126667B1 (es)
PT (1) PT71683B (es)
SU (2) SU1116975A3 (es)
YU (1) YU42977B (es)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
LU88639I2 (fr) * 1982-11-08 1996-02-01 Nycomed Imaging S A Agents de contraste pour rayons x
US5191119A (en) * 1983-10-20 1993-03-02 Cook Imaging Corp. Process for producing non-ionic radiographic contrast media utilizing N-allylation
JPH0662472B2 (ja) * 1984-01-31 1994-08-17 三井東圧化学株式会社 ポリオキシアルキレン化合物及びその製造方法
WO1988009328A1 (en) * 1987-05-22 1988-12-01 Bracco Industria Chimica S.P.A. Preparation of 5-acylamino-2,4,6-triiodo- or tribromo-benzoic acid derivatives
DE3731542A1 (de) * 1987-09-17 1989-03-30 Schering Ag Neue dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6-triiod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
JPH02126118U (es) * 1989-03-28 1990-10-17
JPH036623U (es) * 1989-06-05 1991-01-23
US5232685A (en) * 1989-11-03 1993-08-03 Schering Aktiengesellschaft Nonionic x-ray contrast medium with high iodine content
FR2673180B1 (fr) * 1991-02-25 1994-03-04 Guerbet Sa Nouveaux composes non ioniques poly-iodes, procede de preparation, produit de contraste les contenant.
IT1252180B (it) * 1991-12-10 1995-06-05 Bracco Ind Chimica Spa 5,5'-(1,3-propandiil) bis (imino (2-osso-2,1-etandiil)acetilimino)-bis(2,4,6-triiodo-1,3-benzendicarbossiamidi),loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
IT1274027B (it) * 1994-03-03 1997-07-14 Zambon Spa Processo per la preparazione e purificazione di mezzi di contrasto iodurati
US6310243B1 (en) * 1994-09-23 2001-10-30 Nycomed Imaging As Iodinated x-ray contrast media
GB9419203D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
DE69601525T2 (de) * 1995-05-23 1999-06-24 Fructamine S.P.A., Mozzo Verfahren zur herstellung von dicarbonsäurechlorid
US5575905A (en) * 1995-05-24 1996-11-19 Nycomed Imaging As Iodination process
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
US5847212A (en) * 1997-04-21 1998-12-08 Abbott Laboratories Process for the preparation of iohexol
US6751290B2 (en) 1998-09-08 2004-06-15 Veritas Pharmaceuticals, Inc. Radiographic assessment of tissue after exposure to a compound
US6723746B2 (en) * 1998-09-08 2004-04-20 Veritas Pharmaceuticals, Inc. Functional radiographic imaging methods and agents
US20040170561A1 (en) * 1998-09-08 2004-09-02 Jesse Salb Functional radiographic imaging methods and agents
US20010038682A1 (en) * 1998-09-08 2001-11-08 Jesse Salb Radiographic assessment of tissue response to compounds
US6226352B1 (en) * 1998-09-08 2001-05-01 Veritas Pharmaceuticals, Inc. System and method for radiographic imaging of tissue
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
SE517168C2 (sv) 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
IT1319671B1 (it) * 2000-12-01 2003-10-23 Bracco Spa Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino)
ES2341296T3 (es) 2001-12-20 2010-06-17 Bone Support Ab Un nuevo sustituto mineral de hueso.
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
US7955234B1 (en) 2007-02-28 2011-06-07 Pursley Michael G Exercise device and method
DK2178568T3 (da) 2007-07-12 2014-07-21 Ge Healthcare As Kontrastmidler
US20100209356A1 (en) 2007-10-12 2010-08-19 Duncan George Wynn Contrast agents
US8202511B2 (en) 2007-10-12 2012-06-19 Ge Healthcare As Contrast agents
EP2200655B1 (en) * 2007-10-12 2012-07-18 GE Healthcare AS Contrast agents
US20100221191A1 (en) 2007-10-12 2010-09-02 Duncan George Wynn Contrast agents
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN102887833B (zh) * 2011-07-21 2014-10-22 浙江司太立制药股份有限公司 一种含碘双聚体造影剂
CA2901528C (en) 2013-02-20 2022-07-26 Bone Support Ab Heat-treated, sintered and micronized hydroxyapatite powder for use in a hardenable bone substitute composition
CN107249570B (zh) 2014-11-21 2022-08-09 丹麦技术大学 用于局部药物释放的凝胶制剂
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
BR112018073493A2 (pt) 2016-05-20 2019-03-26 Technical University Of Denmark composição de marcador palpável, método e kit de partes para identificar e/ou localizar um tumor não palpável, um tumor palpável com maior precisão e/ou um tecido alvo, e, uso de uma composição de marcador palpável
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
WO2020249801A1 (en) 2019-06-12 2020-12-17 Technical University Of Denmark Dissacharide formulations for controlled drug release

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE344166B (es) * 1966-12-13 1972-04-04 Pharmacia Ab
SE315975B (es) * 1967-12-28 1969-10-13 Pharmacia Ab
US3886859A (en) * 1974-04-26 1975-06-03 Gen Electric Compactor brake
CH608189A5 (es) * 1974-12-13 1978-12-29 Savac Ag
FI760068A7 (es) * 1975-02-03 1976-08-04 Schering Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
CH626873A5 (es) * 1977-03-28 1981-12-15 Bracco Ind Chimica Spa

Also Published As

Publication number Publication date
EP0023992A1 (de) 1981-02-18
ES494077A0 (es) 1981-08-01
DK157190B (da) 1989-11-20
NO149171B (no) 1983-11-21
DK157190C (da) 1990-04-23
PL226144A1 (es) 1981-10-16
PL126667B1 (en) 1983-08-31
FI802374A7 (fi) 1981-02-10
IE50148B1 (en) 1986-02-19
US4348377A (en) 1982-09-07
AR223890A1 (es) 1981-09-30
CA1123009A (en) 1982-05-04
PT71683B (en) 1981-06-11
YU42977B (en) 1989-02-28
AU537446B2 (en) 1984-06-21
SU1116975A3 (ru) 1984-09-30
JPS5935913B2 (ja) 1984-08-31
IT1207226B (it) 1989-05-17
EP0023992B1 (de) 1982-06-23
FI73200B (fi) 1987-05-29
IT7925027A0 (it) 1979-08-09
ATE1234T1 (de) 1982-07-15
FI73200C (fi) 1987-09-10
NO149171C (no) 1984-02-29
SU1087052A3 (ru) 1984-04-15
NO802374L (no) 1981-03-26
PT71683A (en) 1980-09-01
DE3060592D1 (en) 1982-08-12
DK343880A (da) 1981-02-10
JPS5629554A (en) 1981-03-24
YU201280A (en) 1983-02-28
IE801683L (en) 1981-02-09
AU6103880A (en) 1981-02-12

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