ES8105276A1 - Procedimiento para preparar una sal de acido mineral de cis-teamina - Google Patents
Procedimiento para preparar una sal de acido mineral de cis-teaminaInfo
- Publication number
- ES8105276A1 ES8105276A1 ES492879A ES492879A ES8105276A1 ES 8105276 A1 ES8105276 A1 ES 8105276A1 ES 492879 A ES492879 A ES 492879A ES 492879 A ES492879 A ES 492879A ES 8105276 A1 ES8105276 A1 ES 8105276A1
- Authority
- ES
- Spain
- Prior art keywords
- salts
- prepared
- cysteamine
- thiazolidines
- mineral acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 3
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical class NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003151 mercaptamine Drugs 0.000 title 1
- -1 2,2-disubstituted thiazolidines Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000003548 thiazolidines Chemical class 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE SALES DE ACIDO MINERAL DE CISTEAMIDA. CONSISTE EN HIDROLIZAR UNA 2,2-DISUSTITUIDA TIAZOLIDINA DE FORMULA GENERAL (I) CON ACIDO MINERAL EN PRESENCIA DE AGUA. SE OBTIENE UN COMPUESTO II, SIENDO R1 Y R2 UN GRUPO ALQUILO DE CADENA RECTA O RAMIFICADA O UN GRUPO FENILO, O R1 SE UNE CON R2 PARA FORMAR UN ANILO; R3, R4, R5 Y R6 SON HIDROGENO O ALQUILO, Y X ES UN RADICAL ACIDO. LA TIAZOLINA 2,2-DISUSTITUIDA SE PREPARA HACIENDO REACCIONAR AMINOALQUIL HIDROGENSULFATO CON UN COMPUESTO CON UN ION DE HIDROSULFURO (-SH) EN PRESENCIA DE UNA CETONA. *FORMULA* AGENTES PROTECTORES DE RADIACION.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8392279A JPS568358A (en) | 1979-07-04 | 1979-07-04 | Production of cysteamine mineral acid salt |
| JP15813079A JPS5681574A (en) | 1979-12-07 | 1979-12-07 | Preparation of 2,2-disubstituted thiazolidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8105276A1 true ES8105276A1 (es) | 1981-06-01 |
| ES492879A0 ES492879A0 (es) | 1981-06-01 |
Family
ID=26424956
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES492879A Granted ES492879A0 (es) | 1979-07-04 | 1980-06-27 | Procedimiento para preparar una sal de acido mineral de cis-teamina |
Country Status (7)
| Country | Link |
|---|---|
| CH (1) | CH643825A5 (es) |
| DE (1) | DE3025461A1 (es) |
| ES (1) | ES492879A0 (es) |
| FR (1) | FR2460926A1 (es) |
| GB (1) | GB2054573B (es) |
| IE (1) | IE49614B1 (es) |
| IT (1) | IT1145439B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0054409B1 (en) * | 1980-12-12 | 1985-09-18 | Fine Organics Limited | Preparation of thiazolidine derivatives |
| DE3742265A1 (de) * | 1987-12-12 | 1989-06-22 | Basf Ag | Verfahren zur herstellung von cysteamin-saeureadditionssalzen |
| IE67043B1 (en) * | 1989-07-14 | 1996-02-21 | Nippon Catalytic Chem Ind | Granular cysteamine hydrochloride and method for production thereof |
| US5256362A (en) * | 1989-07-14 | 1993-10-26 | Nippon Shokubai Co., Ltd. | Method for production of granular cysteamine hydrochloride |
| CN104910128A (zh) * | 2015-06-02 | 2015-09-16 | 安徽兴东化工有限公司 | 一种2,2-二甲基四氢噻唑的制备方法 |
| EP4457210A2 (en) | 2021-12-27 | 2024-11-06 | Recordati Industria Chimica E Farmaceutica SPA | Process for the preparation of cysteamine bitartrate and product so obtained |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD51641A (es) * | ||||
| JPS5441569B2 (es) * | 1971-09-30 | 1979-12-08 | ||
| CH577272A5 (es) * | 1972-07-04 | 1976-07-15 | Givaudan & Cie Sa | |
| JPS5251308A (en) * | 1975-10-22 | 1977-04-25 | Wakunaga Yakuhin Kk | Process for preparation of cysteamines |
| DE2812400C2 (de) * | 1978-03-21 | 1984-10-31 | The Dow Chemical Co., Midland, Mich. | Verfahren zur Herstellung von N-(2-Mercaptoethyl)-alkanamiden und 2-Mercaptoethylamin-hydrochloriden |
-
1980
- 1980-06-17 IE IE1248/80A patent/IE49614B1/en unknown
- 1980-06-27 ES ES492879A patent/ES492879A0/es active Granted
- 1980-06-30 GB GB8021313A patent/GB2054573B/en not_active Expired
- 1980-07-02 IT IT49141/80A patent/IT1145439B/it active
- 1980-07-02 CH CH508980A patent/CH643825A5/fr not_active IP Right Cessation
- 1980-07-03 FR FR8014791A patent/FR2460926A1/fr active Granted
- 1980-07-04 DE DE19803025461 patent/DE3025461A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2460926A1 (fr) | 1981-01-30 |
| IT1145439B (it) | 1986-11-05 |
| FR2460926B1 (es) | 1985-04-26 |
| IE801248L (en) | 1981-01-04 |
| GB2054573B (en) | 1983-07-06 |
| DE3025461A1 (de) | 1981-01-29 |
| IE49614B1 (en) | 1985-10-30 |
| CH643825A5 (fr) | 1984-06-29 |
| ES492879A0 (es) | 1981-06-01 |
| GB2054573A (en) | 1981-02-18 |
| IT8049141A0 (it) | 1980-07-02 |
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