[go: up one dir, main page]

ES8105149A1 - Un procedimiento para la preparacion de la mezcla antibioti-ca a-42355 - Google Patents

Un procedimiento para la preparacion de la mezcla antibioti-ca a-42355

Info

Publication number
ES8105149A1
ES8105149A1 ES492227A ES492227A ES8105149A1 ES 8105149 A1 ES8105149 A1 ES 8105149A1 ES 492227 A ES492227 A ES 492227A ES 492227 A ES492227 A ES 492227A ES 8105149 A1 ES8105149 A1 ES 8105149A1
Authority
ES
Spain
Prior art keywords
factor
mixture
procedure
antibiotic
antibiotic mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492227A
Other languages
English (en)
Other versions
ES492227A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES492227A0 publication Critical patent/ES492227A0/es
Publication of ES8105149A1 publication Critical patent/ES8105149A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE LA MEZCLA ANTIBIOTICA A-42355. CONSTA DE LAS SIGUIENTES ETAPAS: 1. CULTIVAR <<ASPERGILLUS NIDULANS>>, VAR. ROSENS NRRL 11440, EN UN MEDIO DE CULTIVO QUE CONTIENE FUENTES ASIMILABLES DE CARBOHIDRATO, DE NITROGENO Y E SALES INORGANICAS EN CONDICIONES DE FERMENTACION AEROBIA SUMERGIDA, HASTA QUE SE PRODUCE UNA CANTIDAD SUSTANCIAL DE ACTIVIDAD ANTIBIOTICA. 2. OPCIONALMENTE SEPARAR LA MEZCLA ANTIBIOTICA A-42355 DEL MEDIO DE CULTIVO. 3. OPCIONALMENTE AISLAR LOS FACTORES A, B, D Y H DE A-30912. SE OBTIENE UNA MEZCLA ANTIBIOTICA A-4355 QUE CONTIENE LOS FACTORES A, B, D Y H DE A-30912, Y UN FACTOR A DE A-30912, UN FACTOR B DE A-30912, UN FACTOR D DE A-30912 Y UN FACTOR H DE A30912, TODOS ELLOS ANTIBIOTICOS.
ES492227A 1979-06-08 1980-06-06 Un procedimiento para la preparacion de la mezcla antibioti-ca a-42355 Expired ES8105149A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4674479A 1979-06-08 1979-06-08
US06/126,078 US4288549A (en) 1979-06-08 1980-03-03 Method of producing the A-30912 antibiotics

Publications (2)

Publication Number Publication Date
ES492227A0 ES492227A0 (es) 1981-05-16
ES8105149A1 true ES8105149A1 (es) 1981-05-16

Family

ID=26724253

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492227A Expired ES8105149A1 (es) 1979-06-08 1980-06-06 Un procedimiento para la preparacion de la mezcla antibioti-ca a-42355

Country Status (17)

Country Link
US (1) US4288549A (es)
EP (1) EP0021684A1 (es)
JP (1) JPS5635988A (es)
AR (1) AR222553A1 (es)
AU (1) AU5901580A (es)
CA (1) CA1154695A (es)
DD (1) DD153213A5 (es)
DK (1) DK244680A (es)
ES (1) ES8105149A1 (es)
FI (1) FI801772A7 (es)
FR (1) FR2458587A1 (es)
GB (1) GB2058078A (es)
GR (1) GR69261B (es)
IT (1) IT1209228B (es)
PL (1) PL224774A1 (es)
PT (1) PT71349A (es)
RO (1) RO79494B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4968608A (en) * 1987-10-07 1990-11-06 Merck & Co., Inc. Process for antifungal fermentation product
US4931352A (en) * 1987-10-07 1990-06-05 Merck & Co., Inc. Antifungal fermentation product
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
US5202309A (en) * 1989-06-30 1993-04-13 Merck & Co., Inc. Antibiotic cyclopeptide fermentation product
US5021341A (en) * 1990-03-12 1991-06-04 Merck & Co., Inc. Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
JPH0370872U (es) * 1989-11-06 1991-07-17
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents
US5021403A (en) * 1990-03-19 1991-06-04 Merck & Co., Inc. Antibiotic agents
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US8560369B2 (en) * 2007-11-01 2013-10-15 Red Hat, Inc. Systems and methods for technical support based on a flock structure
US10282701B2 (en) * 2007-11-20 2019-05-07 Red Hat, Inc. Web-based technical issue assignments based on technical support groups having handled a highest number of technical requests
US20100256074A1 (en) * 2008-06-25 2010-10-07 Chaim Eidelman Processes for preparing high purity aza cyclohexapeptides
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途
CN103724403B (zh) * 2012-10-12 2018-02-16 重庆乾泰生物医药有限公司 一种棘白菌素b的分离纯化方法和用途
CN114907989B (zh) * 2022-05-09 2023-06-27 中国科学院青岛生物能源与过程研究所 一种阿尼芬净前体棘白菌素b高产菌株及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024246A (en) * 1975-10-02 1977-05-17 Eli Lilly And Company Antibiotic A-22082 and process for production thereof
US4024245A (en) * 1975-10-02 1977-05-17 Eli Lilly And Company Antibiotic A-30912 and process for production thereof

Also Published As

Publication number Publication date
ES492227A0 (es) 1981-05-16
DD153213A5 (de) 1981-12-30
GR69261B (es) 1982-05-12
IT1209228B (it) 1989-07-16
IT8022585A0 (it) 1980-06-05
FI801772A7 (fi) 1981-01-01
AU5901580A (en) 1981-01-22
JPS5635988A (en) 1981-04-08
PT71349A (en) 1980-07-01
GB2058078A (en) 1981-04-08
AR222553A1 (es) 1981-05-29
PL224774A1 (es) 1981-03-13
FR2458587A1 (fr) 1981-01-02
DK244680A (da) 1980-12-09
RO79494A (fr) 1982-07-06
US4288549A (en) 1981-09-08
RO79494B (ro) 1987-08-31
EP0021684A1 (en) 1981-01-07
CA1154695A (en) 1983-10-04

Similar Documents

Publication Publication Date Title
ES8105149A1 (es) Un procedimiento para la preparacion de la mezcla antibioti-ca a-42355
ES466791A1 (es) Procedimiento para la produccion de esterastina.
ES485074A1 (es) Un metodo de produccion de la mezcla antibiotica a-21978
SE8802165L (sv) Foerbaettringar i och haenfoerande till fermentation
ES462288A1 (es) Procedimiento para la obtencion de azabiciclohexanonas sus- tituidas.
ES8402693A1 (es) Un metodo de cultivar hidroponicamente una planta.
SE8007845L (sv) Terapeutiska kompositioner, innehallande nya indol-(2,3-a)kinolizidiner som aktiv betsandsdel i blandning med ett for administreringsformen i fraga lempat, i och for sig kent bindemedel
ES8504250A1 (es) Un procedimiento para la preparacion del antibiotico a47934
ATE15693T1 (de) Zellkultur-verfahren.
ES523113A0 (es) Un procedimiento mejorado para inocular semillas agricolas con microorganismos beneficiosos.
DK157035C (da) Biologisk ren mikroorganismestamme samt fremgangsmaade til fremstilling af et dyrkningsprodukt heraf til anvendelse som et hudpraeparat
ES529062A0 (es) Un procedimiento para la produccion de una mezcla de sulfosuccionatos de dialquilo activa como detergente
ES8101544A1 (es) Procedimiento para la preparacion de derivados de uretano
ES2043884T3 (es) Metodo de gran rendimiento para la preparacion de algodon a partir de celulas cultivadas.
GB1500965A (en) Cyclic ether antibiotics
ES475853A1 (es) Un procedimiento para la preparacion de los factores a, b, c, y d del antibiotico a-40104
ES8504935A1 (es) Un metodo de produccion de un antibiotico
SU940700A1 (ru) Удмуртский способ осветлени в смешанных молодн ках естественного происхождени
DK0387712T3 (da) WS7622A-, B-, C- og D-stoffer, derivater deraf og fremgangsmåder til fremstilling deraf samt anvendelse deraf
ES8502729A1 (es) &#34;un procedimiento para producir el complejo antibiotico m 9226&#34;
GB2087878B (en) Preparation of nocardicin by fermentation
BG43523A3 (en) Means for growth regulation of plants
ES8102592A1 (es) Procedimiento de preparar antibioticos sisomicinicos.
SE7707366L (sv) Forfarande for framstellning av 7alfa-metoxi-cefalosporansyraderivat
BG37679A3 (en) Method for reproduction of plants by cultivating tissues