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ES8104201A1 - Procedimiento para la preparacion de derivados de nonapepti-dos y decapeptidos de hormona liberadora de hormona luteini-zante - Google Patents

Procedimiento para la preparacion de derivados de nonapepti-dos y decapeptidos de hormona liberadora de hormona luteini-zante

Info

Publication number
ES8104201A1
ES8104201A1 ES492289A ES492289A ES8104201A1 ES 8104201 A1 ES8104201 A1 ES 8104201A1 ES 492289 A ES492289 A ES 492289A ES 492289 A ES492289 A ES 492289A ES 8104201 A1 ES8104201 A1 ES 8104201A1
Authority
ES
Spain
Prior art keywords
preparation
alcohil
leucyl
formula
nonapeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492289A
Other languages
English (en)
Other versions
ES492289A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26221428&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8104201(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/047,661 external-priority patent/US4234571A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES492289A0 publication Critical patent/ES492289A0/es
Publication of ES8104201A1 publication Critical patent/ES8104201A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE NONAPEPTIDOS Y DECAPEPTIDOS DE LH-RH Y DE SUS SALES FARMACEUTICAMENTE ACEPTABLES. LOS POLIPEPTIDOS INDICADOS PUEDEN SER SINTETIZADOS POR ADICION SECUENCIAL DE UNO O MAS AMINOACIDOS A UNA CADENA DE PEPTIDOS EN CRECIMIENTO. LA FORMULA QUE REPRESENTA A LOS CITADOS POLIPEPTIDOS ES LA SIGUIENTE: (PIRO)GLU-HIS-V-SER-W-Y-ARG-PRO-Z, DONDE V ES TRIPTOFILO, FENILALANILO O 3-(1-NAFTIL)-L-ALANILO; W ES TIROSILO, FENILALANILO O 3-(1-PENTAFLUOROFENIL)-L-ALANILO; X ES UN RESTO D-AMINOACIDO. DONDE R ES UN RADICAL QUE CONTIENE ARILO CARBOCILICO, O UN RADICAL CARBOCILICO SATURADO; Y ES LEUCILO, ISOLEUCILO, NOR-LEUCILO O N-METIL-LEUCILO; Z ES GLICINAMIDO O -NH-R ELEVADO A 1, EN DONDE R ELEVADO A 1 ES ALCOHILO INFERIOR, CICLOALCOHILO, FLUO-ALCOHILO INFERIOR A *FORMULA*, EN DONDE R ELEVADO A 2 ES HIDROGENO O ALCOHILO INFERIOR. *FORMULA*
ES492289A 1979-06-11 1980-06-10 Procedimiento para la preparacion de derivados de nonapepti-dos y decapeptidos de hormona liberadora de hormona luteini-zante Expired ES8104201A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/047,661 US4234571A (en) 1979-06-11 1979-06-11 Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
FR7927754A FR2458538A1 (fr) 1979-06-11 1979-11-09 Derives nonapeptidiques et decapeptidiques de l'hormone liberant l'hormone luteinisante, leur procede de production et composition pharmaceutique les contenant

Publications (2)

Publication Number Publication Date
ES492289A0 ES492289A0 (es) 1981-04-01
ES8104201A1 true ES8104201A1 (es) 1981-04-01

Family

ID=26221428

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492289A Expired ES8104201A1 (es) 1979-06-11 1980-06-10 Procedimiento para la preparacion de derivados de nonapepti-dos y decapeptidos de hormona liberadora de hormona luteini-zante

Country Status (22)

Country Link
EP (1) EP0021234B1 (es)
AU (1) AU539495B2 (es)
CA (1) CA1157851A (es)
CS (1) CS228133B2 (es)
DD (1) DD152542A5 (es)
DE (3) DE3069013D1 (es)
DK (2) DK149046C (es)
ES (1) ES8104201A1 (es)
FI (1) FI72527C (es)
GB (1) GB2054603B (es)
GR (1) GR69259B (es)
HK (1) HK17486A (es)
IE (1) IE49946B1 (es)
IL (1) IL60282A (es)
IT (1) IT1149971B (es)
MY (1) MY8600324A (es)
NL (1) NL930103I2 (es)
NO (1) NO151896C (es)
NZ (1) NZ193984A (es)
PL (1) PL126655B1 (es)
PT (1) PT71366A (es)
YU (2) YU42217B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4318905A (en) * 1980-06-23 1982-03-09 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues
ZA815447B (en) * 1980-08-29 1982-08-25 Salk Inst For Biological Studi Peptides affecting gonadal function
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
CS230614B1 (en) * 1982-08-06 1984-08-13 Martin Cs Flegel Analogues of realising factor for luteining and folliculstimulated hormon
CH661206A5 (fr) * 1983-09-23 1987-07-15 Debiopharm Sa Procede pour la preparation d'un medicament destine au traitement de maladies hormonodependantes.
US4632979A (en) * 1984-06-18 1986-12-30 Tulane Educational Fund Therapeutic LHRH analogs
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
EP0206807A3 (en) * 1985-06-28 1988-01-20 Kissei Pharmaceutical Co. Ltd. Novel amino acid derivatives
US4761398A (en) * 1986-08-18 1988-08-02 Embrex, Inc. Method of inducing birds to molt
US4851211A (en) * 1986-11-25 1989-07-25 Abbott Laboratories LHRH analog formulations
US5028430A (en) * 1987-05-08 1991-07-02 Syntex (U.S.A.) Inc. Delivery systems for the controlled administration of LHRH analogs
EP0400065B1 (en) * 1988-02-10 1997-08-27 TAP Pharmaceuticals Inc. Lhrh analog
US5110904A (en) * 1989-08-07 1992-05-05 Abbott Laboratories Lhrh analogs
US6353030B1 (en) 1990-08-01 2002-03-05 Novartis Ag Relating to organic compounds
JP2944419B2 (ja) * 1993-05-10 1999-09-06 ノバルティス アクチエンゲゼルシャフト 持続性遊離組成物中の薬理学的活性成分の安定
US6248713B1 (en) 1995-07-11 2001-06-19 Biogen, Inc. Cell adhesion inhibitors
US6239108B1 (en) 1996-07-11 2001-05-29 Biogen, Inc. Cell adhesion inhibitors
ES2285735T3 (es) 1996-07-25 2007-11-16 Biogen Idec Inc Modelo molecular para inhibidores de vla-4.
US6686350B1 (en) 1996-07-25 2004-02-03 Biogen, Inc. Cell adhesion inhibitors
CN1148350C (zh) 1998-05-28 2004-05-05 拜奥根有限公司 新型VLA-4抑制剂:oMePUPA-V
MXPA02001449A (es) 1999-08-13 2002-07-02 Biogen Inc Inhibidores de adhesion de celdas.
US6875743B1 (en) 2000-11-28 2005-04-05 Biogen, Inc. Cell adhesion inhibitors
US7196112B2 (en) 2004-07-16 2007-03-27 Biogen Idec Ma Inc. Cell adhesion inhibitors
CN107024474B (zh) 2012-06-22 2020-11-06 霍夫曼-拉罗奇有限公司 用于检测体液中的分析物的方法和器件
US11376220B2 (en) 2017-06-30 2022-07-05 Therio, LLC Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50142563A (es) * 1974-04-26 1975-11-17
DE2438350C3 (de) * 1974-08-09 1979-06-13 Hoechst Ag, 6000 Frankfurt Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2617646C2 (de) * 1976-04-22 1986-07-31 Hoechst Ag, 6230 Frankfurt Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
NL930103I2 (nl) 1997-05-01
DK152734B (da) 1988-05-02
IT8022519A0 (it) 1980-06-03
IT1149971B (it) 1986-12-10
IL60282A0 (en) 1980-09-16
DD152542A5 (de) 1981-12-02
NL930103I1 (nl) 1993-10-01
NO151896B (no) 1985-03-18
PT71366A (en) 1980-07-01
IL60282A (en) 1983-09-30
NO801729L (no) 1980-12-12
DE3069013D1 (en) 1984-09-27
FI72527B (fi) 1987-02-27
DK79384D0 (da) 1984-02-20
AU539495B2 (en) 1984-10-04
EP0021234B1 (en) 1984-08-22
CS228133B2 (en) 1984-05-14
HK17486A (en) 1986-03-21
YU82387A (en) 1988-04-30
ES492289A0 (es) 1981-04-01
DE19375028I2 (de) 2000-12-07
FI801856A7 (fi) 1980-12-12
EP0021234A1 (en) 1981-01-07
FI72527C (fi) 1987-06-08
NO151896C (no) 1985-06-26
GR69259B (es) 1982-05-12
DK79384A (da) 1984-02-20
DK152734C (da) 1988-10-10
PL126655B1 (en) 1983-08-31
IE801193L (en) 1980-12-11
YU46315B (sh) 1993-05-28
YU155380A (en) 1984-02-29
GB2054603A (en) 1981-02-18
DK149046C (da) 1986-08-18
DK248880A (da) 1980-12-12
YU42217B (en) 1988-06-30
DE3021736A1 (de) 1980-12-18
CA1157851A (en) 1983-11-29
GB2054603B (en) 1983-02-09
MY8600324A (en) 1986-12-31
AU5917680A (en) 1980-12-18
PL224852A1 (es) 1981-03-27
NZ193984A (en) 1982-09-07
IE49946B1 (en) 1986-01-22
DK149046B (da) 1985-12-30

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