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ES8103756A1 - Un procedimiento para preparar compuestos de cefem - Google Patents

Un procedimiento para preparar compuestos de cefem

Info

Publication number
ES8103756A1
ES8103756A1 ES492003A ES492003A ES8103756A1 ES 8103756 A1 ES8103756 A1 ES 8103756A1 ES 492003 A ES492003 A ES 492003A ES 492003 A ES492003 A ES 492003A ES 8103756 A1 ES8103756 A1 ES 8103756A1
Authority
ES
Spain
Prior art keywords
unsubstituted
hydrogen
cephem compounds
protecting group
hal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492003A
Other languages
English (en)
Other versions
ES492003A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of ES492003A0 publication Critical patent/ES492003A0/es
Publication of ES8103756A1 publication Critical patent/ES8103756A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE CEMEN DE FORMULA: *FORMULA* Y SUS SALES Y ESTERES FARMACEUTICAMENTE ACEPTABLES. DONDE X ES HALOGENO, R ELEVADO A 1 ES HIDROGENO O UN GRUPO PROTECTOR DE GRUPO AMINO. R ELEVADO A 2 ES ALCOHILO INFERIOR Y R ELEVADO A 3 ES HIDROGENO O UN GRUPO PROTECTOR DE GRUPO CARBOXI. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE HIDROXIIMINO DE FORMULA: *FORMULA* CON UN REACTIVO DE INTRODUCCION DE ALCOHILO INFERIOR, EN UN DISOLVENTE INERTE Y A UNA TEMPERATURA COMPRENDIDA ENTRE -20 Y -50GC. ESTOS COMPUESTOS PRESENTAN INTERES FARMACOLOGICO.
ES492003A 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem Expired ES8103756A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11549878A JPS5543011A (en) 1978-09-20 1978-09-20 7-halothiazolylalkoxyiminoacetamido-3-cephem compound

Publications (2)

Publication Number Publication Date
ES492003A0 ES492003A0 (es) 1981-03-16
ES8103756A1 true ES8103756A1 (es) 1981-03-16

Family

ID=14663989

Family Applications (4)

Application Number Title Priority Date Filing Date
ES484270A Expired ES8100300A1 (es) 1978-09-20 1979-09-19 Un procedimiento para preparar compuestos de cefem
ES492003A Expired ES8103756A1 (es) 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem
ES492001A Expired ES8103754A1 (es) 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem
ES492002A Expired ES8103755A1 (es) 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES484270A Expired ES8100300A1 (es) 1978-09-20 1979-09-19 Un procedimiento para preparar compuestos de cefem

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES492001A Expired ES8103754A1 (es) 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem
ES492002A Expired ES8103755A1 (es) 1978-09-20 1980-05-30 Un procedimiento para preparar compuestos de cefem

Country Status (12)

Country Link
US (1) US4254119A (es)
JP (1) JPS5543011A (es)
AU (1) AU528117B2 (es)
CA (1) CA1127632A (es)
CH (1) CH644129A5 (es)
DE (1) DE2937868A1 (es)
ES (4) ES8100300A1 (es)
FR (1) FR2436787A1 (es)
GB (1) GB2031425B (es)
IE (1) IE48942B1 (es)
IT (1) IT7968839A0 (es)
SE (1) SE7907764L (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4372952A (en) * 1978-07-31 1983-02-08 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
GR78221B (es) * 1980-02-01 1984-09-26 Ciba Geigy Ag
EP0054512A3 (de) * 1980-12-12 1983-08-03 Ciba-Geigy Ag Cephalosporinester, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
IT1142096B (it) * 1980-12-15 1986-10-08 Fujisawa Pharmaceutical Co Derivati dell'acido 7-acilammino cefalosporanico e procedimenti per la loro preparazione
JPS57154190A (en) * 1980-12-22 1982-09-22 Fujisawa Pharmaceut Co Ltd 7-substituted cephalosporanic acid derivative and its preparation
DE3177090D1 (en) * 1980-12-31 1989-09-28 Fujisawa Pharmaceutical Co 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
GB9519883D0 (en) * 1995-09-29 1995-11-29 Fujisawa Pharmaceutical Co New cephem compounds
CA2753387C (en) * 2009-02-23 2017-01-24 Forest Laboratories Holdings Limited Novel cephem compounds useful for the treatment of bacterial infections
USD628753S1 (en) 2010-01-11 2010-12-07 Soldier Technology and Armor Research Industries, LLC Forearm protection system
USD638583S1 (en) 2010-01-11 2011-05-24 Soldier Technology and Armor Research Industries, LLC Torso protection assembly
USD644380S1 (en) 2010-01-11 2011-08-30 Soldier Technology and Armor Research Industries, LLC Upper arm protection system
USD630385S1 (en) 2010-01-11 2011-01-04 Soldier Technology and Armor Research Industries, LLC Shin guard protection system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4152433A (en) * 1976-03-12 1979-05-01 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions

Also Published As

Publication number Publication date
GB2031425A (en) 1980-04-23
CH644129A5 (de) 1984-07-13
CA1127632A (en) 1982-07-13
AU5064479A (en) 1980-03-27
ES492002A0 (es) 1981-03-16
ES492001A0 (es) 1981-03-16
AU528117B2 (en) 1983-04-14
GB2031425B (en) 1983-02-02
IE791777L (en) 1980-03-20
ES8103754A1 (es) 1981-03-16
US4254119A (en) 1981-03-03
IE48942B1 (en) 1985-06-26
FR2436787B1 (es) 1983-07-18
SE7907764L (sv) 1980-03-21
JPS5543011A (en) 1980-03-26
ES492003A0 (es) 1981-03-16
DE2937868A1 (de) 1980-04-03
IT7968839A0 (it) 1979-09-19
FR2436787A1 (fr) 1980-04-18
ES484270A0 (es) 1980-11-01
ES8100300A1 (es) 1980-11-01
ES8103755A1 (es) 1981-03-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601