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ES8103020A1 - Procedimiento de preparacion de amino-eteres oxidos - Google Patents

Procedimiento de preparacion de amino-eteres oxidos

Info

Publication number
ES8103020A1
ES8103020A1 ES493092A ES493092A ES8103020A1 ES 8103020 A1 ES8103020 A1 ES 8103020A1 ES 493092 A ES493092 A ES 493092A ES 493092 A ES493092 A ES 493092A ES 8103020 A1 ES8103020 A1 ES 8103020A1
Authority
ES
Spain
Prior art keywords
lower alkyl
amino
different
same
therapy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493092A
Other languages
English (en)
Other versions
ES493092A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Industrielle de Produits de Synthese Ste
Original Assignee
Industrielle de Produits de Synthese Ste
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Industrielle de Produits de Synthese Ste filed Critical Industrielle de Produits de Synthese Ste
Publication of ES8103020A1 publication Critical patent/ES8103020A1/es
Publication of ES493092A0 publication Critical patent/ES493092A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE AMINO-ETERES OXIDOS DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDOS. LOS SIMBOLOS EMPLEADOS EN LA FORMULA I TIENEN LOS SIGUIENTES SIGNIFICADOS: R1 ES UN ALCOHILO INFERIOR; R2 Y R3 PUEDEN SER HIDROGENO O ALCOHILO INFERIOR; R4 ES UN GRUPO FENILO O FENOXI EVENTUALMENTE SUSTITUIDO POR HALOGENOS, RADICALES ALCOHILO, RADICALES ALCOXI, RADICALES NITRO, PIRIDILO Y/O ALCOHILO INFERIOR. EL PROCEDIMIENTO DE OBTENCION SE BASA EN LA CONDENSACION DE UN COMPUESTO FORMULA: SOBRE UN ALCOHOLATO DE FORMULA: *FORMULA* SIENDO A O B EL RADICAL (II), DONDE LOS SIMBOLOS DE LOS GRUPOS TIENEN EL SIGNIFICADO ANTES INDICADO. *FORMULA*.
ES493092A 1979-07-11 1980-07-04 Procedimiento de preparacion de amino-eteres oxidos Granted ES493092A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7917986A FR2460919A1 (fr) 1979-07-11 1979-07-11 Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
ES8103020A1 true ES8103020A1 (es) 1981-02-16
ES493092A0 ES493092A0 (es) 1981-02-16

Family

ID=9227765

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493092A Granted ES493092A0 (es) 1979-07-11 1980-07-04 Procedimiento de preparacion de amino-eteres oxidos

Country Status (11)

Country Link
US (1) US4301163A (es)
JP (1) JPS5615250A (es)
BE (1) BE884212A (es)
CA (1) CA1148547A (es)
CH (1) CH644348A5 (es)
DE (1) DE3026201A1 (es)
ES (1) ES493092A0 (es)
FR (1) FR2460919A1 (es)
GB (1) GB2054588B (es)
IT (1) IT1136190B (es)
NL (1) NL190237C (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4824868A (en) * 1982-09-07 1989-04-25 Ciba-Geigy Corporation Propylamine derivatives useful for the treatment of dementia
DE3372283D1 (en) * 1982-09-07 1987-08-06 Ciba Geigy Ag Propylamine derivatives, process for their preparation, pharmaceutical compositions containing these compounds, and their therapeutical use
US4692469A (en) * 1982-09-07 1987-09-08 Ciba-Geigy Corporation Propylamine derivatives
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
US5266599A (en) * 1989-02-20 1993-11-30 Jouveinal S.A. Use of (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylamine to increase gastric discharge in a subject
US5245080A (en) * 1989-02-20 1993-09-14 Jouveinal Sa (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-N-propylamine, process for preparing it and its therapeutical use
FR2643369B1 (fr) * 1989-02-20 1991-07-05 Jouveinal Sa La (+) 1-((3,4,5-trimethoxy) benzyloxymethyl)-1-phenyl-n,n-dimethyl-n-propylamine, son procede de preparation et son application en therapeutique
EP0593559A1 (en) * 1991-07-05 1994-04-27 MERCK SHARP & DOHME LTD. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
EP0593557B1 (en) * 1991-07-05 1996-01-31 MERCK SHARP & DOHME LTD. Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
US5495047A (en) * 1991-07-10 1996-02-27 Merck, Sharp & Dohme (Ltd.) Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
WO1993001165A2 (en) * 1991-07-10 1993-01-21 Merck Sharp & Dohme Limited Aromatic compounds, compositions containing them and their use in therapy
US5328927A (en) * 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
GB9211193D0 (en) * 1992-05-27 1992-07-08 Merck Sharp & Dohme Therapeutic agents
AU4718093A (en) * 1992-07-31 1994-03-03 Merck Sharp & Dohme Limited Substituted amines as tachykinin receptor antagonists
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
DE69524962D1 (de) * 1994-08-22 2002-02-14 Welfide Corp Benzolderivate und deren medizinische verwendung
WO2003059880A1 (en) 2002-01-11 2003-07-24 Sankyo Company, Limited Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
BR0312501A (pt) * 2002-07-10 2005-04-12 Warner Lambert Co Combinação de um inibidor alostérico ou metaloproteinase de matriz-13 com um inibidor de ciclooxigenase-2 diferente de celecoxib ou valdecoxib
MXPA05000405A (es) * 2002-07-10 2005-03-23 Warner Lambert Co Composiciones gastrointestinales.
US6986901B2 (en) * 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
US20040010035A1 (en) * 2002-07-15 2004-01-15 Ciociola Arthur A. Gastrointestinal compositions
US7910617B2 (en) 2004-02-24 2011-03-22 Sankyo Company, Limited Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound
SE0400968D0 (sv) * 2004-04-14 2004-04-14 Astrazeneca Ab Aryl glycine ether derivatives and their use
US7879913B2 (en) * 2005-06-28 2011-02-01 Catholic Healthcare West Iptakalim hydrochloride for decreasing nicotine use
KR20090021346A (ko) * 2006-06-06 2009-03-03 안티브 테라퓨틱스 인크. 트리메부틴 및 ｎ-데스메틸 트리메부틴 염

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2649445A (en) * 1948-02-28 1953-08-18 Bristol Lab Chloracetic acid ester of diphenyl ethanols
ES251290A1 (es) * 1958-08-21 1960-04-01 Parke Davis & Co Un procedimiento para la producciën de alcohilaminas arilsustituidas
GB1119835A (en) * 1964-07-20 1968-07-17 Analyses Et De Rech S Biolog M Process for the preparation of basic ethers
US4194009A (en) * 1974-01-10 1980-03-18 Eli Lilly And Company Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4207343A (en) * 1978-06-22 1980-06-10 Eli Lilly And Company 1-Phenyl-3-(substituted phenoxy)propylamines

Also Published As

Publication number Publication date
US4301163A (en) 1981-11-17
CH644348A5 (fr) 1984-07-31
NL190237B (nl) 1993-07-16
GB2054588A (en) 1981-02-18
DE3026201A1 (de) 1981-02-26
IT1136190B (it) 1986-08-27
FR2460919A1 (fr) 1981-01-30
JPS5615250A (en) 1981-02-14
GB2054588B (en) 1983-06-29
NL190237C (nl) 1993-12-16
BE884212A (fr) 1981-01-08
JPS6253504B2 (es) 1987-11-10
DE3026201C2 (es) 1990-11-08
NL8003601A (nl) 1981-01-13
FR2460919B1 (es) 1983-11-10
CA1148547A (en) 1983-06-21
US4301163B1 (es) 1990-01-23
ES493092A0 (es) 1981-02-16
IT8012595A0 (it) 1980-07-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010217