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ES8103077A1 - New phenothiazine derivatives - Google Patents

New phenothiazine derivatives

Info

Publication number
ES8103077A1
ES8103077A1 ES490315A ES490315A ES8103077A1 ES 8103077 A1 ES8103077 A1 ES 8103077A1 ES 490315 A ES490315 A ES 490315A ES 490315 A ES490315 A ES 490315A ES 8103077 A1 ES8103077 A1 ES 8103077A1
Authority
ES
Spain
Prior art keywords
phenothiazine derivatives
stands
image
general formula
equal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490315A
Other languages
Spanish (es)
Other versions
ES490315A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES8103077A1 publication Critical patent/ES8103077A1/en
Publication of ES490315A0 publication Critical patent/ES490315A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention relates to new phenothiazine derivatives of the general formula (I) or an acid addition salt thereof, < IMAGE > wherein R stands for a group of the general formula (IIa), (IIb) or (IIc), < IMAGE > and in these latter formulae X stands for hydrogen, a C1-4 alkyl group, halogen atom or a nitro group and n is equal to 1, 2 or 3, with the proviso that if n is equal to 2 or 3, the X substituents attached to the aromatic ring may be the same or different. The compounds are useful as neuroleptic agents.
ES490315A 1979-04-06 1980-04-07 PROCEDURE FOR THE PREPARATION OF NEW PHENOTIAZINE DERIVATIVES OR THEIR ACIDAL ADDITIONAL SALTS Granted ES490315A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79GO1442A HU179190B (en) 1979-04-06 1979-04-06 Process for preparing new phenthiazine derivatives

Publications (2)

Publication Number Publication Date
ES8103077A1 true ES8103077A1 (en) 1981-02-16
ES490315A0 ES490315A0 (en) 1981-02-16

Family

ID=10996889

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490315A Granted ES490315A0 (en) 1979-04-06 1980-04-07 PROCEDURE FOR THE PREPARATION OF NEW PHENOTIAZINE DERIVATIVES OR THEIR ACIDAL ADDITIONAL SALTS

Country Status (16)

Country Link
JP (1) JPS6043345B2 (en)
AT (1) AT375355B (en)
BE (1) BE882535A (en)
CA (1) CA1128940A (en)
CH (1) CH643843A5 (en)
CS (1) CS214704B2 (en)
DD (1) DD150060A5 (en)
DE (1) DE3013502C2 (en)
ES (1) ES490315A0 (en)
FR (1) FR2453164A1 (en)
GB (1) GB2047694B (en)
HU (1) HU179190B (en)
IT (1) IT1148812B (en)
PL (1) PL127329B1 (en)
SU (1) SU925250A3 (en)
YU (1) YU42663B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4471116A (en) * 1982-07-28 1984-09-11 Hoffmann-La Roche Inc. Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines
JPH0568560U (en) * 1991-11-05 1993-09-17 理照 大島 Grip strength tools
JP3932785B2 (en) 1999-08-25 2007-06-20 株式会社村田製作所 Method for manufacturing piezoelectric body
RU2167157C1 (en) * 2000-02-11 2001-05-20 Государственный научный центр РФ "НИОПИК" Method of synthesis of 2-trifluoromethyl-10-(3-chloropropyl)-phenothiazine
US20060111346A1 (en) * 2004-11-23 2006-05-25 Fazix Corporation. Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same
PL444423A1 (en) 2023-04-15 2024-10-21 Ml System Spółka Akcyjna Method of manufacturing a laminar layered photovoltaic plate and a laminar layered photovoltaic plate manufactured by this method

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL277672A (en) * 1961-04-26

Also Published As

Publication number Publication date
GB2047694B (en) 1983-02-02
PL223267A1 (en) 1981-01-30
IT8021186A0 (en) 1980-04-04
HU179190B (en) 1982-09-28
JPS55153776A (en) 1980-11-29
BE882535A (en) 1980-09-30
CS214704B2 (en) 1982-05-28
YU42663B (en) 1988-10-31
DE3013502A1 (en) 1980-10-16
DD150060A5 (en) 1981-08-12
CH643843A5 (en) 1984-06-29
YU93380A (en) 1983-01-21
FR2453164A1 (en) 1980-10-31
JPS6043345B2 (en) 1985-09-27
CA1128940A (en) 1982-08-03
ES490315A0 (en) 1981-02-16
FR2453164B1 (en) 1983-04-15
IT1148812B (en) 1986-12-03
ATA184080A (en) 1983-12-15
DE3013502C2 (en) 1985-02-07
PL127329B1 (en) 1983-10-31
SU925250A3 (en) 1982-04-30
AT375355B (en) 1984-07-25
GB2047694A (en) 1980-12-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303