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ES8103061A1 - Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina - Google Patents

Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Info

Publication number
ES8103061A1
ES8103061A1 ES491000A ES491000A ES8103061A1 ES 8103061 A1 ES8103061 A1 ES 8103061A1 ES 491000 A ES491000 A ES 491000A ES 491000 A ES491000 A ES 491000A ES 8103061 A1 ES8103061 A1 ES 8103061A1
Authority
ES
Spain
Prior art keywords
pirimidine
isopropylamine
procedure
preparation
hydroxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491000A
Other languages
English (en)
Other versions
ES491000A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes de Produits Chimiques SA
Original Assignee
Societe dEtudes de Produits Chimiques SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes de Produits Chimiques SA filed Critical Societe dEtudes de Produits Chimiques SA
Publication of ES8103061A1 publication Critical patent/ES8103061A1/es
Publication of ES491000A0 publication Critical patent/ES491000A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS HIDROXILICOS DE ISOPROPILAMINO-PIRIMIDINA DE FORMULA (I) DONDE A4, A5, Y A6 SON INDEPENDIENTEMENTE, HIDROGENO O UN GRUPO HIDROXI, PERO CON LA CONDICION DE QUE AL MENOS UNO DE ELLOS NO SEA HIDROGENO. DICHO PROCEDIMIENTO SE FUNDAMENTA EN LA REDUCCION DE LA CORRESPONDIENTE 2-ISOPROPILAMINO-ARALCOHILOXI O -ALCOHILOXI-PIRIMIDINA CON HIDROGENO, BAJO PRESION Y EN PRESION DE UN CATALIZADOR DE HIDROGENACION. COMO CATALIZADOR DE HIDROGENACION PUEDE EMPLEARSE PALADIO. LOS COMPUESTOS OBTENIDOS ON DE EMPLEO EN EL TRATAMIENTO DE NUROPATIAS Y DE DISTROFIAS MUSCULARES. *FORMULA*.
ES491000A 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina Granted ES491000A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7914987 1979-04-30

Publications (2)

Publication Number Publication Date
ES8103061A1 true ES8103061A1 (es) 1981-02-16
ES491000A0 ES491000A0 (es) 1981-02-16

Family

ID=10504858

Family Applications (2)

Application Number Title Priority Date Filing Date
ES491000A Granted ES491000A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina
ES490999A Granted ES490999A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES490999A Granted ES490999A0 (es) 1979-04-30 1980-04-29 Procedimiento de preparacion de derivados hidroxilicos de isopropilamino-pirimidina

Country Status (26)

Country Link
JP (2) JPS55145671A (es)
AR (2) AR222870A1 (es)
AT (2) AT380013B (es)
BE (2) BE882593A (es)
CH (2) CH645361A5 (es)
DK (2) DK183880A (es)
EG (2) EG14259A (es)
ES (2) ES491000A0 (es)
FI (2) FI66358C (es)
FR (2) FR2455588A1 (es)
GB (2) GB2055801B (es)
HK (2) HK55583A (es)
IE (2) IE49709B1 (es)
IN (2) IN154066B (es)
IT (2) IT1141487B (es)
LU (2) LU82332A1 (es)
MA (1) MA18824A1 (es)
MX (2) MX6514E (es)
MY (2) MY8400204A (es)
NL (2) NL8002271A (es)
NO (2) NO154055C (es)
NZ (2) NZ193422A (es)
OA (2) OA06527A (es)
PT (2) PT71154A (es)
SG (2) SG22283G (es)
ZA (2) ZA801958B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63145595U (es) * 1987-03-13 1988-09-26
JPS645795U (es) * 1987-06-26 1989-01-13
JPH01100695U (es) * 1987-12-21 1989-07-06
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
USD500447S1 (en) * 2003-08-07 2005-01-04 Kranson Industries Oval bottle
USD505864S1 (en) * 2003-08-07 2005-06-07 Kranson Industries Oval bottle

Also Published As

Publication number Publication date
IE800864L (en) 1980-10-30
BE882594A (fr) 1980-07-31
ES8103060A1 (es) 1981-02-16
FI66358B (fi) 1984-06-29
IN154067B (es) 1984-09-15
GB2055801A (en) 1981-03-11
ES490999A0 (es) 1981-02-16
HK55683A (en) 1983-11-25
AT380012B (de) 1986-03-25
IT1141296B (it) 1986-10-01
SG22283G (en) 1983-12-16
OA06525A (fr) 1981-07-31
AT380013B (de) 1986-03-25
AR222869A1 (es) 1981-06-30
JPS55145670A (en) 1980-11-13
NL8002271A (nl) 1980-11-03
EG14284A (en) 1983-09-30
MX6514E (es) 1985-06-26
ATA221680A (de) 1985-08-15
GB2054556B (en) 1983-01-26
IT8021542A0 (it) 1980-04-22
NO154055C (no) 1986-07-09
FI801084A7 (fi) 1980-10-31
ZA801960B (en) 1981-04-29
NO154055B (no) 1986-04-01
JPS55145671A (en) 1980-11-13
FR2455588A1 (fr) 1980-11-28
NO801235L (no) 1980-10-31
CH645633A5 (en) 1984-10-15
AR222870A1 (es) 1981-06-30
NZ193422A (en) 1981-12-15
ZA801958B (en) 1981-04-29
FI801083A7 (fi) 1980-10-31
JPS6116272B2 (es) 1986-04-28
IT1141487B (it) 1986-10-01
IE49709B1 (en) 1985-11-27
PT71154A (en) 1980-05-01
LU82333A1 (fr) 1980-07-02
FR2455589A1 (fr) 1980-11-28
NZ193421A (en) 1981-11-19
FI66359B (fi) 1984-06-29
IE800865L (en) 1980-10-30
FR2455588B1 (es) 1983-04-15
MY8400203A (en) 1984-12-31
MX5878E (es) 1984-08-16
DK183780A (da) 1980-10-31
IN154066B (es) 1984-09-15
NL8002272A (nl) 1980-11-03
GB2055801B (en) 1983-02-09
JPS6116273B2 (es) 1986-04-28
ATA221580A (de) 1985-08-15
BE882593A (fr) 1980-07-31
NO801234L (no) 1980-10-31
MA18824A1 (fr) 1980-12-31
IT8021543A0 (it) 1980-04-22
IE49591B1 (en) 1985-10-30
ES491000A0 (es) 1981-02-16
LU82332A1 (fr) 1980-07-02
DK183880A (da) 1980-10-31
HK55583A (en) 1983-11-25
PT71155A (en) 1980-05-01
OA06527A (fr) 1981-07-31
FR2455589B1 (es) 1981-07-10
EG14259A (en) 1983-09-30
NO154056C (no) 1986-07-09
NO154056B (no) 1986-04-01
CH645361A5 (en) 1984-09-28
FI66358C (fi) 1984-10-10
GB2054556A (en) 1981-02-18
FI66359C (fi) 1984-10-10
MY8400204A (en) 1984-12-31
SG22583G (en) 1983-12-16

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