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ES557478A0 - Un procedimiento para preparar un vector de expresion replicable - Google Patents

Un procedimiento para preparar un vector de expresion replicable

Info

Publication number
ES557478A0
ES557478A0 ES557478A ES557478A ES557478A0 ES 557478 A0 ES557478 A0 ES 557478A0 ES 557478 A ES557478 A ES 557478A ES 557478 A ES557478 A ES 557478A ES 557478 A0 ES557478 A0 ES 557478A0
Authority
ES
Spain
Prior art keywords
preparing
procedure
expression vector
replicable expression
replicable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES557478A
Other languages
English (en)
Other versions
ES8801706A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858503358A external-priority patent/GB8503358D0/en
Priority claimed from GB868600979A external-priority patent/GB8600979D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES557478A0 publication Critical patent/ES557478A0/es
Publication of ES8801706A1 publication Critical patent/ES8801706A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES557478A 1985-02-09 1987-03-31 Un procedimiento para preparar un vector de expresion replicable Expired ES8801706A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858503358A GB8503358D0 (en) 1985-02-09 1985-02-09 Compounds
GB868600979A GB8600979D0 (en) 1986-01-16 1986-01-16 Compounds

Publications (2)

Publication Number Publication Date
ES557478A0 true ES557478A0 (es) 1988-02-16
ES8801706A1 ES8801706A1 (es) 1988-02-16

Family

ID=26288793

Family Applications (4)

Application Number Title Priority Date Filing Date
ES551770A Expired ES8706724A1 (es) 1985-02-09 1986-02-07 Un procedimiento para preparar activador de plasminogeno de tipo tejido modificado.
ES557478A Expired ES8801706A1 (es) 1985-02-09 1987-03-31 Un procedimiento para preparar un vector de expresion replicable
ES557477A Expired ES8800354A1 (es) 1985-02-09 1987-03-31 Un procedimiento para preparar un polimero de adn
ES557479A Expired ES8801707A1 (es) 1985-02-09 1987-03-31 Un procedimiento para preparar una celula huesped transformada con un vector de expresion replicable

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES551770A Expired ES8706724A1 (es) 1985-02-09 1986-02-07 Un procedimiento para preparar activador de plasminogeno de tipo tejido modificado.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES557477A Expired ES8800354A1 (es) 1985-02-09 1987-03-31 Un procedimiento para preparar un polimero de adn
ES557479A Expired ES8801707A1 (es) 1985-02-09 1987-03-31 Un procedimiento para preparar una celula huesped transformada con un vector de expresion replicable

Country Status (6)

Country Link
EP (1) EP0201153A3 (es)
AU (1) AU5330286A (es)
DK (1) DK62586A (es)
ES (4) ES8706724A1 (es)
GR (1) GR860364B (es)
PT (1) PT81999B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661469A (en) * 1984-08-08 1987-04-28 Survival Technology, Inc. t-PA composition capable of being absorbed into the blood stream and method of administration
EP0191814B1 (en) * 1984-08-08 1992-11-04 Survival Technology, Inc. Protein absorption enhancing agents
DE3682104D1 (de) * 1985-04-22 1991-11-28 Genentech Inc Plasminogenaktivator-mutante des menschlichen gewebes, verfahren und zwischenprodukte dafuer und diese mutante verwendende zusammensetzungen.
US5714372A (en) * 1985-04-22 1998-02-03 Genentech, Inc. Tissue plasminogen activator variants
US5736134A (en) * 1985-04-22 1998-04-07 Genentech, In.C Tissue plasminogen activator variants
US5756093A (en) * 1985-04-22 1998-05-26 Genentech, Inc. Tissue plasminogen activator variants
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
DK623186A (da) * 1985-12-23 1987-08-26 Chiron Corp Polypeptid med vaevsplasminogen-aktivator-virkning
DK43387A (da) * 1986-01-29 1987-07-30 Beecham Group Plc Fibrinolytisk enzym
PT84589B (en) * 1986-04-02 1989-05-09 Beecham Group Plc Process for preparing a fibrinolytic enzyme
PT84588B (en) * 1986-04-02 1989-05-09 Beecham Group Plc Process for preparing a fibrinolytic enzyme
GB8619098D0 (en) * 1986-08-05 1986-09-17 Wellcome Found Combination
DK323587D0 (da) * 1987-06-25 1987-06-25 Novo Industri As Protein
WO1988005081A2 (en) * 1986-12-30 1988-07-14 Cetus Corporation Novel plasminogen activator
US5302390A (en) * 1987-07-01 1994-04-12 Beecham Group Plc Hybrid proteins of human plasminogen and human t-PA, pharmaceutical compositions and methods of treatment
IL87276A (en) * 1987-08-03 1995-07-31 Fujisawa Pharmaceutical Co Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same
US5258180A (en) * 1988-09-02 1993-11-02 Genetech, Inc. Tissue plasminogen activator having fibrin specific properties and deletion of amino acids 466-970, compositions and methods of treatment
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
US5190756A (en) * 1989-12-01 1993-03-02 Genentech, Inc. Methods and materials for expression of human plasminogen variant
US5087572A (en) * 1989-12-01 1992-02-11 Genentech, Inc. Dna encoding human plasminogen modified at the cleavage site
ES2107041T3 (es) * 1992-06-03 1997-11-16 Genentech Inc Variantes de activador de plasminogeno tisular obtenidos por glicosilacion, que presentan propiedades terapeuticas.
ES2066697B1 (es) * 1992-12-29 1995-08-16 Azkoyen Ind Sa Perfeccionamientos introducidos en columnas expendedoras automaticas de productos.
AU2091397A (en) * 1996-03-12 1997-10-01 Novo Nordisk A/S Novel achromobacter lyticus protease variants
JP4383530B2 (ja) 1996-04-05 2009-12-16 ノバルティス バクシンズ アンド ダイアグノスティックス， インコーポレーテッド 細胞巨大分子合成の阻害が減少したアルファウイルスベクター
US6706504B1 (en) 1996-11-12 2004-03-16 The Scripps Research Institute Tissue type plasminogen activator (t-PA) variants: compositions and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
US4753879A (en) * 1984-08-27 1988-06-28 Biogen N.V. Modified tissue plasminogen activators
DE3682104D1 (de) * 1985-04-22 1991-11-28 Genentech Inc Plasminogenaktivator-mutante des menschlichen gewebes, verfahren und zwischenprodukte dafuer und diese mutante verwendende zusammensetzungen.

Also Published As

Publication number Publication date
ES8801707A1 (es) 1988-02-16
ES551770A0 (es) 1987-07-01
ES557477A0 (es) 1987-10-16
ES8706724A1 (es) 1987-07-01
DK62586D0 (da) 1986-02-07
EP0201153A2 (en) 1986-11-12
GR860364B (en) 1986-06-10
PT81999A (en) 1986-03-01
ES8800354A1 (es) 1987-10-16
ES8801706A1 (es) 1988-02-16
DK62586A (da) 1986-08-10
EP0201153A3 (en) 1987-10-07
PT81999B (en) 1987-12-22
ES557479A0 (es) 1988-02-16
AU5330286A (en) 1986-08-14

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