ES546884A0 - Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona - Google Patents
Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-onaInfo
- Publication number
- ES546884A0 ES546884A0 ES546884A ES546884A ES546884A0 ES 546884 A0 ES546884 A0 ES 546884A0 ES 546884 A ES546884 A ES 546884A ES 546884 A ES546884 A ES 546884A ES 546884 A0 ES546884 A0 ES 546884A0
- Authority
- ES
- Spain
- Prior art keywords
- dialqui
- bencimidazole
- hidroxi
- etil
- lamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 methoxyphenethyl Chemical group 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229940052760 dopamine agonists Drugs 0.000 abstract 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/649,465 US4554287A (en) | 1984-09-12 | 1984-09-12 | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8605491A1 ES8605491A1 (es) | 1986-03-16 |
| ES546884A0 true ES546884A0 (es) | 1986-03-16 |
Family
ID=24604906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES546884A Expired ES8605491A1 (es) | 1984-09-12 | 1985-09-11 | Un procedimiento para preparar un derivado de 7-(2-(dialqui-lamino)-etil)-4-hidroxi-1,3-bencimidazol-2-ona |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4554287A (es) |
| EP (1) | EP0175525B1 (es) |
| JP (1) | JPS6168473A (es) |
| AT (1) | ATE53025T1 (es) |
| AU (1) | AU586187B2 (es) |
| CA (1) | CA1255685A (es) |
| DE (1) | DE3577849D1 (es) |
| DK (1) | DK407885A (es) |
| ES (1) | ES8605491A1 (es) |
| GR (1) | GR852189B (es) |
| PT (1) | PT81109B (es) |
| ZA (1) | ZA856943B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3586123D1 (de) * | 1984-08-15 | 1992-07-02 | Schering Ag | Neue dopamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. |
| DE3728695A1 (de) * | 1987-08-25 | 1989-03-09 | Schering Ag | Neue benzimidazol-derivate |
| IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
| GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
| TW356468B (en) * | 1995-09-15 | 1999-04-21 | Astra Pharma Prod | Benzothiazolone compounds useful as beta2-adrenoreceptor and dopamine DA2 receptor agonists process for preparing same and pharmaceutical compositions containing same |
| GB9526511D0 (en) * | 1995-12-23 | 1996-02-28 | Astra Pharma Prod | Pharmaceutically active compounds |
| TW200738658A (en) | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
| TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| TW200833670A (en) | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
| GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
| KR20110017456A (ko) | 2008-06-18 | 2011-02-21 | 아스트라제네카 아베 | 호흡기 장애의 치료를 위한 베타2-아드레날린성 수용체 효능제로서 작용하는 벤족사지논 유도체 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4070478A (en) * | 1977-02-17 | 1978-01-24 | Merck & Co., Inc. | Benzimidazole substituted alanines |
| US4179505A (en) * | 1977-03-30 | 1979-12-18 | Janssen Pharmaceutica N.V. | 5-[4-(Diarylmethyl)-1-piperazinylalkyl]benzimidazole derivatives |
| CA1108619A (en) * | 1977-08-12 | 1981-09-08 | Carl H. Ross | 4-hydroxy-2-benzimidazolinone derivatives and the preparation thereof |
| US4314944A (en) * | 1980-08-22 | 1982-02-09 | Smithkline Corporation | 4-Aminoalkyl-7-hydroxy-2(3H)-indolones |
-
1984
- 1984-09-12 US US06/649,465 patent/US4554287A/en not_active Expired - Fee Related
-
1985
- 1985-09-05 CA CA000490062A patent/CA1255685A/en not_active Expired
- 1985-09-06 AU AU47144/85A patent/AU586187B2/en not_active Ceased
- 1985-09-06 EP EP85306335A patent/EP0175525B1/en not_active Expired - Lifetime
- 1985-09-06 AT AT85306335T patent/ATE53025T1/de not_active IP Right Cessation
- 1985-09-06 DE DE8585306335T patent/DE3577849D1/de not_active Expired - Fee Related
- 1985-09-06 DK DK407885A patent/DK407885A/da not_active Application Discontinuation
- 1985-09-10 GR GR852189A patent/GR852189B/el unknown
- 1985-09-10 JP JP60201480A patent/JPS6168473A/ja active Pending
- 1985-09-11 ES ES546884A patent/ES8605491A1/es not_active Expired
- 1985-09-11 ZA ZA856943A patent/ZA856943B/xx unknown
- 1985-09-11 PT PT81109A patent/PT81109B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6168473A (ja) | 1986-04-08 |
| CA1255685A (en) | 1989-06-13 |
| PT81109B (en) | 1987-07-06 |
| EP0175525A1 (en) | 1986-03-26 |
| US4554287A (en) | 1985-11-19 |
| ES8605491A1 (es) | 1986-03-16 |
| DK407885A (da) | 1986-03-13 |
| GR852189B (es) | 1986-01-10 |
| AU586187B2 (en) | 1989-07-06 |
| PT81109A (en) | 1985-10-01 |
| ZA856943B (en) | 1986-06-25 |
| AU4714485A (en) | 1986-03-20 |
| DK407885D0 (da) | 1985-09-06 |
| ATE53025T1 (de) | 1990-06-15 |
| EP0175525B1 (en) | 1990-05-23 |
| DE3577849D1 (de) | 1990-06-28 |
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