ES531907A0 - Un procedimiento para la preparacion de nuevas indolonas. - Google Patents

Un procedimiento para la preparacion de nuevas indolonas.

Info

Publication number: ES531907A0
Authority: ES; Spain
Prior art keywords: indolones; phenyl; treatment; procedure; preparation
Prior art date: 1982-09-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES531907A

Other languages

English (en)

Other versions

ES8505950A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Corp Belgium

Pfizer Corp SRL

Original Assignee

Pfizer Corp Belgium

Pfizer Corp SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-20

Filing date

1984-04-25

Publication date

1985-06-01

1984-04-25 Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium

1985-06-01 Publication of ES531907A0 publication Critical patent/ES531907A0/es

1985-06-01 Publication of ES8505950A1 publication Critical patent/ES8505950A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Neurosurgery (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Dental Preparations (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES531907A 1982-09-20 1984-04-25 Un procedimiento para la preparacion de nuevas indolonas. Expired ES8505950A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/420,544 US4476307A (en)	1982-09-20	1982-09-20	Heteroylidene indolone compounds

Publications (2)

Publication Number	Publication Date
ES531907A0 true ES531907A0 (es)	1985-06-01
ES8505950A1 ES8505950A1 (es)	1985-06-01

Family

ID=23666904

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES525737A Granted ES525737A0 (es)	1982-09-20	1983-09-19	Un procedimiento para la preparacion de nuevas idolonas.
ES531908A Granted ES531908A0 (es)	1982-09-20	1984-04-25	Un procedimiento para la preparacion de nuevas indolonas.
ES531907A Expired ES8505950A1 (es)	1982-09-20	1984-04-25	Un procedimiento para la preparacion de nuevas indolonas.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES525737A Granted ES525737A0 (es)	1982-09-20	1983-09-19	Un procedimiento para la preparacion de nuevas idolonas.
ES531908A Granted ES531908A0 (es)	1982-09-20	1984-04-25	Un procedimiento para la preparacion de nuevas indolonas.

Country Status (24)

Country	Link
US (1)	US4476307A (es)
EP (1)	EP0104860B1 (es)
JP (1)	JPS5976058A (es)
KR (1)	KR860001270B1 (es)
AT (1)	ATE25972T1 (es)
AU (1)	AU543115B2 (es)
CA (1)	CA1194871A (es)
DD (1)	DD213211A5 (es)
DE (1)	DE3370325D1 (es)
DK (1)	DK157010C (es)
ES (3)	ES525737A0 (es)
FI (1)	FI77446C (es)
GR (1)	GR79732B (es)
HU (1)	HU189747B (es)
IE (1)	IE55923B1 (es)
IL (1)	IL69758A (es)
NO (1)	NO161557C (es)
NZ (1)	NZ205638A (es)
PH (1)	PH18297A (es)
PL (3)	PL141370B1 (es)
PT (1)	PT77360B (es)
SU (1)	SU1272983A3 (es)
YU (4)	YU189283A (es)
ZA (1)	ZA836933B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4879391A (en) *	1982-09-20	1989-11-07	Pfizer Inc.	1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents
US4760083A (en) *	1986-04-10	1988-07-26	E. I. Dupont De Nemours & Company	3,3-disubstituted indolines
US5128352A (en) *	1989-01-10	1992-07-07	Pfizer Inc.	Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides
US5078756A (en) *	1990-01-12	1992-01-07	Major Thomas O	Apparatus and method for purification and recovery of refrigerant
US5158969A (en) *	1991-08-21	1992-10-27	Neurosearch A/S	Indole derivatives as potassium channel blockers
US5760250A (en) *	1991-11-05	1998-06-02	Zeneca Limited	Process for the preparation of 3-(α-methoxy)methylenebenzofuranones and intermediates therefor
DE19949209A1 (de) *	1999-10-13	2001-04-19	Boehringer Ingelheim Pharma	In 5-Stellung substituierte Indolinone, ihre Herstellung und ihre Verwendung als Arzneimittel
US20030225152A1 (en) *	2001-09-27	2003-12-04	Andrews Steven W.	3-(Arylamino)methylene-1, 3-dihydro-2h-indol-2-ones as kinase inhibitors
MXPA04009365A (es) *	2002-03-27	2005-01-25	Lundbeck & Co As H	Metodo para la manufactura de sertindol.
FR2847811B1 (fr) *	2002-11-29	2005-01-07	Oreal	Composition filtrante contenant au moins un derive du dibenzoylmethane et au moins un derive de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one;procede de photostabilisation
FR2847813A1 (fr) *	2002-11-29	2004-06-04	Oreal	Compositions cosmetiques photoprotectrices contenant des derives de 3-(2-azacycloalkylidene)-1,3-dihydro-indol-2-one et utilisations
US7728013B2 (en)	2005-05-10	2010-06-01	Intermune, Inc.	Method of modulating stress-activated protein kinase system
ES2567283T3 (es)	2008-06-03	2016-04-21	Intermune, Inc.	Compuestos y métodos para tratar trastornos inflamatorios y fibróticos
CA2747424C (en)	2008-12-19	2013-06-25	Nippon Soda Co., Ltd.	1-heterodiene derivative and harmful organism control agent
US9012493B2 (en)	2009-11-12	2015-04-21	Nippon Soda Co., Ltd.	1-heterodiene derivative and pest control agent
AR092742A1 (es)	2012-10-02	2015-04-29	Intermune Inc	Piridinonas antifibroticas
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神分裂病を処置するための方法および組成物
CA2943363A1 (en)	2014-04-02	2015-10-08	Intermune, Inc.	Anti-fibrotic pyridinones

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3506683A (en) *	1963-10-07	1970-04-14	Upjohn Co	3-(2-pyrrolidinylidene)-3h-indoles
GB1237008A (en) *	1968-12-18	1971-06-30	Pfizer Ltd	Novel indoline derivatives
US3723457A (en) *	1969-09-30	1973-03-27	Eisai Co Ltd	Indoline-2-one derivatives and preparation thereof
GB1374414A (en) *	1972-06-12	1974-11-20	Sterling Drug Inc	1-acyl-3-amino-alkyl-indoles and their preparation
DE2557342A1 (de) *	1975-12-19	1977-06-30	Hoechst Ag	Basisch substituierte indolderivate und verfahren zu ihrer herstellung

1982
- 1982-09-20 US US06/420,544 patent/US4476307A/en not_active Expired - Fee Related
1983
- 1983-09-16 CA CA000436845A patent/CA1194871A/en not_active Expired
- 1983-09-18 IL IL69758A patent/IL69758A/xx unknown
- 1983-09-19 SU SU833646758A patent/SU1272983A3/ru active
- 1983-09-19 ES ES525737A patent/ES525737A0/es active Granted
- 1983-09-19 EP EP83305484A patent/EP0104860B1/en not_active Expired
- 1983-09-19 FI FI833335A patent/FI77446C/fi not_active IP Right Cessation
- 1983-09-19 KR KR1019830004396A patent/KR860001270B1/ko not_active Expired
- 1983-09-19 HU HU833235A patent/HU189747B/hu unknown
- 1983-09-19 DE DE8383305484T patent/DE3370325D1/de not_active Expired
- 1983-09-19 DK DK425383A patent/DK157010C/da not_active IP Right Cessation
- 1983-09-19 NO NO833367A patent/NO161557C/no unknown
- 1983-09-19 NZ NZ205638A patent/NZ205638A/en unknown
- 1983-09-19 ZA ZA836933A patent/ZA836933B/xx unknown
- 1983-09-19 GR GR72470A patent/GR79732B/el unknown
- 1983-09-19 PT PT77360A patent/PT77360B/pt not_active IP Right Cessation
- 1983-09-19 AT AT83305484T patent/ATE25972T1/de not_active IP Right Cessation
- 1983-09-19 AU AU19252/83A patent/AU543115B2/en not_active Ceased
- 1983-09-19 DD DD83254923A patent/DD213211A5/de unknown
- 1983-09-19 IE IE2193/83A patent/IE55923B1/en not_active IP Right Cessation
- 1983-09-20 PL PL1983250768A patent/PL141370B1/pl unknown
- 1983-09-20 PH PH29565A patent/PH18297A/en unknown
- 1983-09-20 YU YU01892/83A patent/YU189283A/xx unknown
- 1983-09-20 JP JP58174025A patent/JPS5976058A/ja active Granted
- 1983-09-20 PL PL1983243826A patent/PL141609B1/pl unknown
- 1983-09-20 PL PL1983250769A patent/PL141876B1/pl unknown
1984
- 1984-04-25 ES ES531908A patent/ES531908A0/es active Granted
- 1984-04-25 ES ES531907A patent/ES8505950A1/es not_active Expired
1986
- 1986-10-01 YU YU01692/86A patent/YU169286A/xx unknown
- 1986-10-01 YU YU01693/86A patent/YU169386A/xx unknown
- 1986-10-01 YU YU01691/86A patent/YU169186A/xx unknown

Also Published As

Publication number	Publication date
YU189283A (en)	1987-10-31
DK425383A (da)	1984-05-03
ES8505951A1 (es)	1985-06-01
EP0104860A1 (en)	1984-04-04
EP0104860B1 (en)	1987-03-18
US4476307A (en)	1984-10-09
ES8503328A1 (es)	1985-02-16
CA1194871A (en)	1985-10-08
FI77446B (fi)	1988-11-30
HU189747B (en)	1986-07-28
YU169386A (en)	1987-10-31
NO833367L (no)	1984-03-21
NZ205638A (en)	1986-12-05
PL141609B1 (en)	1987-08-31
PL250769A1 (en)	1985-07-02
FI833335A7 (fi)	1984-03-21
IE832193L (en)	1984-03-20
YU169186A (en)	1987-10-31
PL250768A1 (en)	1985-07-02
SU1272983A3 (ru)	1986-11-23
JPS5976058A (ja)	1984-04-28
DK157010C (da)	1990-03-26
IL69758A (en)	1986-12-31
YU169286A (en)	1987-10-31
IE55923B1 (en)	1991-02-27
PT77360A (en)	1983-10-01
FI77446C (fi)	1989-03-10
PL243826A1 (en)	1985-04-24
IL69758A0 (en)	1983-12-30
AU1925283A (en)	1984-03-29
PL141370B1 (en)	1987-07-31
PL141876B1 (en)	1987-09-30
NO161557B (no)	1989-05-22
PH18297A (en)	1985-05-24
KR860001270B1 (ko)	1986-09-04
DD213211A5 (de)	1984-09-05
ES525737A0 (es)	1985-02-16
ES8505950A1 (es)	1985-06-01
ES531908A0 (es)	1985-06-01
PT77360B (en)	1986-05-19
DE3370325D1 (en)	1987-04-23
ATE25972T1 (de)	1987-04-15
AU543115B2 (en)	1985-04-04
ZA836933B (en)	1985-05-29
JPS6241711B2 (es)	1987-09-04
DK157010B (da)	1989-10-30
KR840006239A (ko)	1984-11-22
NO161557C (no)	1989-08-30
FI833335A0 (fi)	1983-09-19
DK425383D0 (da)	1983-09-19
GR79732B (es)	1984-10-31

Publication	Publication Date	Title
ES531908A0 (es)	1985-06-01	Un procedimiento para la preparacion de nuevas indolonas.
ES520988A0 (es)	1984-01-01	Procedimiento para la preparacion de nuevos 6,11-dihidro-dibenzo-(b,e)-tiepin-11-n-alcohilnorescopin-eteres.
LV10449A (lv)	1995-02-20	Jauni hromana un tiohromana atvasinajumi
DE69033703D1 (de)	2001-03-22	Nichtglykosyliertes fgf-4 und dieses enthaltende präparate
NO853698L (no)	1986-03-24	I-substituerte tetralinderivater, fremstilling og anvendel se derav.
ES545155A0 (es)	1986-02-01	Procedimiento para la obtencion de (pirrol-1-il)-fenil-dihi-dropiridazinona
IT8420213A0 (it)	1984-03-23	Procedimento per la preparazione di 1,8-diidrossi-10-acil-9-antroni, in particolare per l'uso nel trattamento di psoriasi.
ES538403A0 (es)	1985-11-01	Procedimiento para la obtencion de antipodas opticos del (+7-1,7-difenil-3-metilaza-7-ciano-8-metil-nonano
ES2188742T3 (es)	2003-07-01	Trapidil para uso en la terapia de cuadros patologicos influenciables por la inmunomodulacion.
DE3378979D1 (en)	1989-02-23	1-acyl-3-pyridylmethylguanidines and their use as antihypertensive agents
AR010304A1 (es)	2000-06-07	Compuestos de dimesilato de cis-1-(3-etoxifenil)-1-4-fenilpiperazin-1-il) -4-metilciclohexano; procedimiento para su preparacion y composicionfarmaceutica
ES1015599Y (es)	1992-01-16	Perfil compuesto para la formacion de marcos para cuadros y similares.

Legal Events

Date	Code	Title	Description
1997-05-16	FD1A	Patent lapsed	Effective date: 19970401