ES538172A0 - Procedimiento para la obtencion de derivados de etilendiamina sustituidos - Google Patents
Procedimiento para la obtencion de derivados de etilendiamina sustituidosInfo
- Publication number
- ES538172A0 ES538172A0 ES538172A ES538172A ES538172A0 ES 538172 A0 ES538172 A0 ES 538172A0 ES 538172 A ES538172 A ES 538172A ES 538172 A ES538172 A ES 538172A ES 538172 A0 ES538172 A0 ES 538172A0
- Authority
- ES
- Spain
- Prior art keywords
- ethylendiamine
- derivatives
- procedure
- obtaining substituted
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical class NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH643683 | 1983-12-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES538172A0 true ES538172A0 (es) | 1986-11-16 |
| ES8701142A1 ES8701142A1 (es) | 1986-11-16 |
Family
ID=4309613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538172A Expired ES8701142A1 (es) | 1983-12-01 | 1984-11-30 | Procedimiento para la obtencion de derivados de etilendiamina sustituidos |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0144290A3 (es) |
| JP (1) | JPS60136595A (es) |
| AU (1) | AU3609484A (es) |
| DK (1) | DK571484A (es) |
| ES (1) | ES8701142A1 (es) |
| GR (1) | GR81124B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI88400C (fi) * | 1984-08-06 | 1993-05-10 | Upjohn Co | Foerfarande foer framstaellning av renin inhiberande peptider |
| WO1991006561A1 (en) * | 1989-10-27 | 1991-05-16 | The Upjohn Company | Method for treating hiv and other retroviruses and compounds useful therefor |
| FR2711990B1 (fr) * | 1993-11-05 | 1995-12-08 | Exsymol Sa | Produit pseudodipeptide possédant un groupement imidazole, et applications thérapeutiques, cosmétologiques et agroalimentaires. |
| WO1996004244A1 (en) * | 1994-08-05 | 1996-02-15 | Warwick International Group Limited | Bleach activators |
| JP4484897B2 (ja) * | 1995-12-08 | 2010-06-16 | 生化学工業株式会社 | アミノアルコール誘導体の製造方法 |
| GB9727123D0 (en) * | 1997-12-22 | 1998-02-25 | Int Centre Genetic Eng & Bio | Synthesis of diamines |
| WO2001002363A2 (en) * | 1999-07-06 | 2001-01-11 | Vertex Pharmaceuticals Incorporated | N-substituted glycine derivatives |
| WO2005113582A1 (en) * | 2004-05-22 | 2005-12-01 | Boehringer Ingelheim International Gmbh | Substituted ethane-1,2-diamines for the treatment of alzheimer's disease |
| US8003617B2 (en) | 2004-11-10 | 2011-08-23 | Genzyme Corporation | Methods of treating diabetes mellitus |
| RU2433999C2 (ru) * | 2005-01-26 | 2011-11-20 | Аллерган, Инк. | Амиды 3-арил-3-гидрокси-2-аминопропионовой кислоты, амиды 3-гетероарил-3-гидрокси-2-аминопропионовой кислоты и родственные соединения, обладающие обезболивающим и/или иммуностимулирующим действием |
| HUE026057T2 (en) | 2006-05-09 | 2016-05-30 | Genzyme Corp | Procedures for the Treatment of Fatty Liver Disease, which comprises inhibition of glycosphingolipid synthesis |
| EP2594564B1 (en) * | 2007-05-31 | 2016-09-28 | Genzyme Corporation | 2-acylaminopropanol-type glucosylceramide synthase inhibitors |
| KR20150085139A (ko) | 2007-10-05 | 2015-07-22 | 젠자임 코포레이션 | 세라마이드 유도체로 다낭성 신장질환을 치료하는 방법 |
| EP2320886B1 (en) | 2008-07-28 | 2017-06-28 | Genzyme Corporation | Glucosylceramide synthase inhibition for the treatment of collapsing glomerulopathy and other glomerular disease |
| EP3078373A1 (en) | 2008-10-03 | 2016-10-12 | Genzyme Corporation | 2-acylaminopropanol-type glucosylceramide synthase inhibitor |
| EP3678700B1 (en) * | 2017-09-05 | 2024-06-19 | Merck Sharp & Dohme LLC | Compounds for reducing the viscosity of biological formulations |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4198398A (en) * | 1977-07-12 | 1980-04-15 | Derek Hudson | Enkephalin analogues |
| US4145337A (en) * | 1977-10-11 | 1979-03-20 | Hoffmann-La Roche Inc. | Aminoethylglycine containing polypeptides |
| GB2058077B (en) * | 1979-06-08 | 1983-03-09 | Szelke M | Enkephalin analogues |
| NO812612L (no) * | 1980-08-06 | 1982-02-08 | Ferring Pharma Ltd | Enzym-inhibitorer. |
| CA1245217A (en) * | 1981-12-10 | 1988-11-22 | Joshua S. Boger | Renin inhibitory peptides having phe su13 xx deletion |
| FI843837L (fi) * | 1983-02-07 | 1984-09-28 | Ferring Ab | Enzyminhibitorer. |
| US4661473A (en) * | 1984-03-27 | 1987-04-28 | Merck & Co., Inc. | Renin inhibitors containing peptide isosteres |
-
1984
- 1984-11-26 EP EP84810575A patent/EP0144290A3/de not_active Withdrawn
- 1984-11-30 DK DK571484A patent/DK571484A/da not_active Application Discontinuation
- 1984-11-30 ES ES538172A patent/ES8701142A1/es not_active Expired
- 1984-11-30 AU AU36094/84A patent/AU3609484A/en not_active Abandoned
- 1984-11-30 GR GR81124A patent/GR81124B/el unknown
- 1984-12-01 JP JP59252849A patent/JPS60136595A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GR81124B (en) | 1985-03-26 |
| JPS60136595A (ja) | 1985-07-20 |
| DK571484D0 (da) | 1984-11-30 |
| DK571484A (da) | 1985-06-02 |
| EP0144290A3 (de) | 1987-05-27 |
| ES8701142A1 (es) | 1986-11-16 |
| EP0144290A2 (de) | 1985-06-12 |
| AU3609484A (en) | 1985-06-06 |
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