ES529803A0 - Mejoras en un procedimiento para la preparacion de una composicion biocida o biostatica que contiene al menos una 3-isotiazolona - Google Patents
Mejoras en un procedimiento para la preparacion de una composicion biocida o biostatica que contiene al menos una 3-isotiazolonaInfo
- Publication number
- ES529803A0 ES529803A0 ES529803A ES529803A ES529803A0 ES 529803 A0 ES529803 A0 ES 529803A0 ES 529803 A ES529803 A ES 529803A ES 529803 A ES529803 A ES 529803A ES 529803 A0 ES529803 A0 ES 529803A0
- Authority
- ES
- Spain
- Prior art keywords
- ppm
- nitrosamine
- biocidal
- compositions
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 230000002599 biostatic effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000013067 intermediate product Substances 0.000 abstract 3
- XKLJHFLUAHKGGU-UHFFFAOYSA-N nitrous amide Chemical compound ON=N XKLJHFLUAHKGGU-UHFFFAOYSA-N 0.000 abstract 3
- MGIYRDNGCNKGJU-UHFFFAOYSA-N isothiazolinone Chemical compound O=C1C=CSN1 MGIYRDNGCNKGJU-UHFFFAOYSA-N 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 abstract 1
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- -1 chloro compound Chemical class 0.000 abstract 1
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 abstract 1
- 150000002823 nitrates Chemical class 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
- 238000001953 recrystallisation Methods 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38385882A | 1982-06-01 | 1982-06-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES529803A0 true ES529803A0 (es) | 1985-05-16 |
| ES8505189A1 ES8505189A1 (es) | 1985-05-16 |
Family
ID=23515027
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522794A Granted ES522794A0 (es) | 1982-06-01 | 1983-05-30 | "un procedimiento para la preparacion de una composicion de 3-isotiazolonas" |
| ES529803A Expired ES8505189A1 (es) | 1982-06-01 | 1984-02-16 | Mejoras en un procedimiento para la preparacion de una composicion biocida o biostatica que contiene al menos una 3-isotiazolona |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522794A Granted ES522794A0 (es) | 1982-06-01 | 1983-05-30 | "un procedimiento para la preparacion de una composicion de 3-isotiazolonas" |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0095907B1 (es) |
| JP (4) | JPH0657701B2 (es) |
| AT (1) | ATE33834T1 (es) |
| CA (1) | CA1189514A (es) |
| DE (1) | DE3376423D1 (es) |
| DK (1) | DK163268C (es) |
| ES (2) | ES522794A0 (es) |
| FI (1) | FI78813C (es) |
| GR (1) | GR79204B (es) |
| HK (1) | HK86188A (es) |
| IE (1) | IE55498B1 (es) |
| IL (1) | IL68816A (es) |
| MY (1) | MY103591A (es) |
| NO (1) | NO163661C (es) |
| SG (1) | SG40588G (es) |
| ZA (1) | ZA833898B (es) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868310A (en) * | 1986-08-04 | 1989-09-19 | Rohm And Haas Company | Process for preparing isothiazolones |
| DE3643183A1 (de) * | 1986-12-18 | 1988-06-30 | Riedel De Haen Ag | Verfahren zur isolierung von isothiazolinonderivaten |
| US4861896A (en) * | 1987-10-26 | 1989-08-29 | Rohm And Haas Company | Preparation of halo substituted isothiazolones |
| US4994574A (en) * | 1987-11-27 | 1991-02-19 | Lein Jr George M | Preparation of isothiazolones |
| US5008395A (en) * | 1988-12-22 | 1991-04-16 | Rohm And Haas Company | Purification of isothiazolones |
| US5068344A (en) * | 1990-01-12 | 1991-11-26 | Rohm And Haas Company | Process for the preparation of salt free, water free 3-isothiazolone compounds |
| CA2056711A1 (en) * | 1990-12-11 | 1992-06-12 | Ramesh B. Petigara | Process for 3-isothiazolone compounds |
| IL97166A (en) | 1991-02-06 | 1995-10-31 | Bromine Compounds Ltd | Process for the preparation of 2-methyl-isothiazolin-3-one compounds |
| GB2274283B (en) * | 1991-05-10 | 1996-01-31 | Sunkyong Ind Ltd | A process for preparing 4-isothiazolin-3-one |
| US5137899A (en) * | 1991-10-30 | 1992-08-11 | Rohm And Haas Company | Bromate as inhibitor of nitrosamine formation for nitrate stabilized isothiazolones and process |
| GB9504629D0 (en) * | 1995-03-08 | 1995-04-26 | Kodak Ltd | A material and method for inhibiting bacterial growth in an aqueous medium |
| EP0774207B1 (de) * | 1995-11-17 | 2001-02-14 | THOR GmbH | Verfahren zur Herstellung von bioziden oder biostatischen 3-Isothiazolinon-Zusammensetzungen |
| KR100212963B1 (ko) * | 1995-12-21 | 1999-08-02 | 조민호 | 안정화된 이소티아졸론 조성물과 이소티아졸론 혼합물의 제조방법 |
| DE10008507A1 (de) * | 2000-02-24 | 2001-08-30 | Bayer Ag | Mikrobizide Mittel |
| KR100703995B1 (ko) * | 2001-05-08 | 2007-04-04 | 에스케이케미칼주식회사 | 이소티아졸론 조성물과 안정화 방법, 및 이를 이용하는미생물의 생장 억제 방법 |
| KR100703996B1 (ko) * | 2001-05-08 | 2007-04-04 | 에스케이케미칼주식회사 | 이소티아졸론 조성물 및 안정화 방법, 그리고 이를이용하는 미생물의 생장 억제방법 |
| KR100493933B1 (ko) * | 2002-09-09 | 2005-06-10 | 주식회사 한서켐 | 2-메틸-4-이소티아졸린-3-온 및 이의 염의 제조 방법 |
| KR101004368B1 (ko) | 2003-07-29 | 2010-12-27 | 에스케이케미칼주식회사 | N,n'-디치환-3,3'-디티오디프로피온아미드 제조방법 및그를 이용한 치환된 3-이소티아졸론 제조방법 |
| JP4999321B2 (ja) * | 2005-11-28 | 2012-08-15 | 株式会社マンダム | 防腐殺菌剤を配合した医薬品、及び防腐殺菌方法 |
| JP5101826B2 (ja) * | 2006-02-28 | 2012-12-19 | 日本曹達株式会社 | イソチアゾロン系化合物を含有する水溶性製剤およびイソチアゾロン系化合物の安定化方法 |
| US7893273B2 (en) | 2006-04-03 | 2011-02-22 | Beijing Tianqing Chemicals Co. Ltd. | Preparation of N-substituted isothiazolinone derivatives |
| BRPI0702299B1 (pt) * | 2006-06-02 | 2017-04-11 | Rohm & Haas | composição microbicida |
| JP2008019215A (ja) * | 2006-07-13 | 2008-01-31 | Nippon Soda Co Ltd | 殺菌剤組成物 |
| CN101417966A (zh) * | 2007-10-25 | 2009-04-29 | 北京天擎化工有限责任公司 | 3-异噻唑啉酮衍生物的连续式生产方法 |
| CN102365022B (zh) * | 2009-03-31 | 2014-05-14 | 长瀬化成株式会社 | 杀微生物剂 |
| WO2011074815A2 (ko) * | 2009-12-16 | 2011-06-23 | 에스케이케미칼주식회사 | N,n'-디알킬-3,3'-디티오디프로피온아미드의 제조방법 |
| JP5897980B2 (ja) | 2012-04-27 | 2016-04-06 | 矢崎総業株式会社 | 同軸電線の端末処理方法及び端末処理装置 |
| CN106018632B (zh) * | 2016-05-11 | 2018-04-10 | 清华大学 | 一种基于离子交换技术富集纯化水中亚硝胺前体物的方法 |
| CN118619860A (zh) * | 2024-08-08 | 2024-09-10 | 山东裕滨新材料有限公司 | 一种n,n'-二甲基-3,3'-二硫代二丙酰胺的纯化工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3523121A (en) * | 1967-03-09 | 1970-08-04 | Rohm & Haas | Certain 2-carbamoyl-3-isothiazolenes |
| US3849430A (en) | 1967-03-09 | 1974-11-19 | Rohm & Haas | Process for the preparation of 3-isothiazolones and 3-hydroxyisothiazoles |
| US4150026A (en) * | 1971-05-12 | 1979-04-17 | Rohm And Haas Company | Metal salt complexes of 3-isothiazolones |
| US4062946A (en) * | 1971-10-18 | 1977-12-13 | Rohm And Haas Company | Parasiticidal animal dip compositions protected against microbial buildup |
| US3870795A (en) * | 1973-02-28 | 1975-03-11 | Rohm & Haas | Stabilization of solutions of 3-isothiazolones employing certain metal nitrates and nitrites |
| US4067878A (en) * | 1976-03-05 | 1978-01-10 | Rohm And Haas Company | Stabilization of solutions of 3-isothiazolones |
-
1983
- 1983-05-18 CA CA000428388A patent/CA1189514A/en not_active Expired
- 1983-05-27 DE DE8383303064T patent/DE3376423D1/de not_active Expired
- 1983-05-27 EP EP83303064A patent/EP0095907B1/en not_active Expired
- 1983-05-27 AT AT83303064T patent/ATE33834T1/de not_active IP Right Cessation
- 1983-05-30 ES ES522794A patent/ES522794A0/es active Granted
- 1983-05-30 FI FI831920A patent/FI78813C/fi not_active IP Right Cessation
- 1983-05-30 IL IL68816A patent/IL68816A/xx not_active IP Right Cessation
- 1983-05-30 GR GR71510A patent/GR79204B/el unknown
- 1983-05-30 ZA ZA833898A patent/ZA833898B/xx unknown
- 1983-05-30 NO NO831917A patent/NO163661C/no not_active IP Right Cessation
- 1983-05-31 JP JP58096868A patent/JPH0657701B2/ja not_active Expired - Lifetime
- 1983-05-31 IE IE1285/83A patent/IE55498B1/en not_active IP Right Cessation
- 1983-05-31 JP JP2183860A patent/JPH07119164B2/ja not_active Expired - Lifetime
- 1983-05-31 DK DK244083A patent/DK163268C/da not_active IP Right Cessation
-
1984
- 1984-02-16 ES ES529803A patent/ES8505189A1/es not_active Expired
-
1988
- 1988-06-21 SG SG405/88A patent/SG40588G/en unknown
- 1988-07-20 MY MYPI88000811A patent/MY103591A/en unknown
- 1988-10-27 HK HK861/88A patent/HK86188A/en not_active IP Right Cessation
-
1994
- 1994-12-20 JP JP6316815A patent/JPH0816043B2/ja not_active Expired - Lifetime
-
1997
- 1997-06-10 JP JP9152300A patent/JP2866840B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20050212 |