ES513522A0 - "un procedimiento para obtener insulina humana". - Google Patents

"un procedimiento para obtener insulina humana".

Info

Publication number: ES513522A0
Authority: ES; Spain
Prior art keywords: procedure; human insulin; obtaining human; obtaining; insulin
Prior art date: 1981-06-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES513522A

Other languages

English (en)

Other versions

ES8304430A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis Vaccines and Diagnostics Inc

Original Assignee

Cetus Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-06-29

Filing date

1982-06-28

Publication date

1983-03-01

1982-06-28 Application filed by Cetus Corp filed Critical Cetus Corp

1983-03-01 Publication of ES513522A0 publication Critical patent/ES513522A0/es

1983-03-01 Publication of ES8304430A1 publication Critical patent/ES8304430A1/es

Status Expired legal-status Critical Current

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 1
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ES513522A 1981-06-29 1982-06-28 "un procedimiento para obtener insulina humana". Expired ES8304430A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US27833181A	1981-06-29	1981-06-29

Publications (2)

Publication Number	Publication Date
ES513522A0 true ES513522A0 (es)	1983-03-01
ES8304430A1 ES8304430A1 (es)	1983-03-01

Family

ID=23064574

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES513522A Expired ES8304430A1 (es)	1981-06-29	1982-06-28	"un procedimiento para obtener insulina humana".

Country Status (12)

Country	Link
US (1)	USH245H (es)
EP (1)	EP0070632A3 (es)
JP (1)	JPS58501227A (es)
AU (1)	AU556980B2 (es)
CA (1)	CA1201074A (es)
DK (1)	DK84583A (es)
ES (1)	ES8304430A1 (es)
IL (1)	IL66102A0 (es)
NO (1)	NO830682L (es)
PT (1)	PT75075B (es)
WO (1)	WO1983000164A1 (es)
ZA (1)	ZA824218B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0090433A1 (en) *	1982-03-31	1983-10-05	Genetics Institute, Inc.	Creation of DNA sequences encoding modified proinsulin precursors
DE3245665A1 (de) *	1982-05-04	1983-11-10	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur herstellung permanenter tierischer und humaner zellinien und deren verwendung
US5670371A (en) *	1983-07-15	1997-09-23	Bio-Technology General Corp.	Bacterial expression of superoxide dismutase
DK58285D0 (da) *	1984-05-30	1985-02-08	Novo Industri As	Peptider samt fremstilling og anvendelse deraf
US4767709A (en)	1984-06-28	1988-08-30	The Johns Hopkins University	Growth-related hormones
PH25772A (en) *	1985-08-30	1991-10-18	Novo Industri As	Insulin analogues, process for their preparation
US5496924A (en) *	1985-11-27	1996-03-05	Hoechst Aktiengesellschaft	Fusion protein comprising an interleukin-2 fragment ballast portion
ES2090006T3 (es) *	1986-05-20	1996-10-16	Gen Hospital Corp	Evaluacion de la expresion de preproinsulina, proinsulina o insulina.
US6348327B1 (en) *	1991-12-06	2002-02-19	Genentech, Inc.	Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
US6001604A (en) *	1993-12-29	1999-12-14	Bio-Technology General Corp.	Refolding of proinsulins without addition of reducing agents
US20180057920A1 (en) *	2016-08-31	2018-03-01	General Electric Company	Grain refinement in in706 using laves phase precipitation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5210872B2 (es) *	1973-07-14	1977-03-26
US4082613A (en) *	1976-04-23	1978-04-04	The Regents Of The University Of Minnesota	Process for the production of insulin by genetically transformed fungal cells
US4411994A (en) *	1978-06-08	1983-10-25	The President And Fellows Of Harvard College	Protein synthesis
GR71912B (es) *	1978-08-11	1983-08-16	Univ California
GR70279B (es) *	1979-09-12	1982-09-03	Univ California
DE3001928A1 (de) *	1980-01-19	1981-08-06	Hoechst Ag, 6000 Frankfurt	Genprodukt eines hoeheren organismus aus einem dieses gen enthaltenden mikroorganismus
EP0036258A3 (en)	1980-03-14	1982-02-10	Cetus Corporation	Process for producing aspartame
US4338397A (en) *	1980-04-11	1982-07-06	President And Fellows Of Harvard College	Mature protein synthesis
DK582381A (da) *	1981-01-02	1982-07-03	Univ New York	Remkombinat plasmid til anvendelse ved bakteriel kloning

1982
- 1982-06-15 ZA ZA824218A patent/ZA824218B/xx unknown
- 1982-06-18 PT PT75075A patent/PT75075B/pt unknown
- 1982-06-21 IL IL66102A patent/IL66102A0/xx unknown
- 1982-06-25 EP EP82303340A patent/EP0070632A3/en not_active Withdrawn
- 1982-06-25 JP JP57502369A patent/JPS58501227A/ja active Pending
- 1982-06-25 AU AU87623/82A patent/AU556980B2/en not_active Ceased
- 1982-06-25 WO PCT/US1982/000858 patent/WO1983000164A1/en not_active Ceased
- 1982-06-28 ES ES513522A patent/ES8304430A1/es not_active Expired
- 1982-06-29 CA CA000406245A patent/CA1201074A/en not_active Expired
1983
- 1983-02-24 DK DK84583A patent/DK84583A/da not_active Application Discontinuation
- 1983-02-28 NO NO830682A patent/NO830682L/no unknown
1984
- 1984-06-27 US US06/625,176 patent/USH245H/en not_active Abandoned

Also Published As

Publication number	Publication date
PT75075A (en)	1982-07-01
EP0070632A3 (en)	1983-06-29
PT75075B (en)	1983-12-28
IL66102A0 (en)	1982-09-30
CA1201074A (en)	1986-02-25
DK84583D0 (da)	1983-02-24
JPS58501227A (ja)	1983-07-28
ES8304430A1 (es)	1983-03-01
AU556980B2 (en)	1986-11-27
WO1983000164A1 (en)	1983-01-20
EP0070632A2 (en)	1983-01-26
AU8762382A (en)	1983-02-02
DK84583A (da)	1983-02-24
NO830682L (no)	1983-02-28
ZA824218B (en)	1983-04-27
USH245H (en)	1987-04-07

Publication	Publication Date	Title
ES511123A0 (es)	1983-02-16	Un procedimiento para la preparacion de un dihidroxi-compuesto.
ES512561A0 (es)	1983-08-01	Un procedimiento para la preparacion de un eter 2-hidroxi-3-alcoxi-propilglicerilico.
ES508935A0 (es)	1983-06-01	"procedimiento para la obtencion de un compuesto polipeptidico tiolado".
ES512076A0 (es)	1983-02-01	"un procedimiento para la preparacion de piridin- y piracin-derivados".
ES499238A0 (es)	1982-08-01	Un procedimiento para la preparacion de insulina humana o esteres de insulina.
ES511124A0 (es)	1983-06-16	Un procedimiento para la preparacion de un dihidroxi-compuesto.
ES514845A0 (es)	1983-05-01	"un procedimiento para preparar insulina humana o derivados de treomina b30 de insulina humana".
ES511663A0 (es)	1983-07-01	Un procedimiento para la preparacion de un heteropoliacido.
ES513522A0 (es)	1983-03-01	"un procedimiento para obtener insulina humana".
ES515295A0 (es)	1983-06-01	"un procedimiento para la preparacion de imidazoquinazolinas".
ES517459A0 (es)	1983-12-16	Un procedimiento para preparar un dentifrico estable.
ES514652A0 (es)	1983-08-16	"un procedimiento para preparar compuestos de cefem".
ES509312A0 (es)	1983-03-16	Un procedimiento para la preparacion de 1-3-hidroxi-4-metoxibenzoil-3-hidroxi-2-pirrolidinona.
ES509432A0 (es)	1983-03-16	Un procedimiento para la preparacion de arilaminas.
ES514981A0 (es)	1983-06-01	"un procedimiento para producir 2-cloropiridinas".
ES516184A0 (es)	1983-10-01	"un metodo para la preparacion de 3-fenil-1-indanaminas".
ES515305A0 (es)	1983-10-16	"un procedimiento para la preparacion de o-alquil s,s-dialquil fosforoditioatos".
ES514572A0 (es)	1983-08-16	"un procedimiento para la preparacion de glutation".
ES510286A0 (es)	1983-04-01	"un procedimiento para la preparacion de nuevas fluoro-prostaciclinas".
ES514571A0 (es)	1983-11-01	"un procedimiento para la preparacion de glutation".
ES510928A0 (es)	1983-08-01	"un procedimiento para la preparacion de mercapto-acil-carnitinas".
ES508294A0 (es)	1982-11-01	"un procedimiento para preparar n-arilsulfenil-n-diariloxifosfinilmetilglicinatos de alcohilo".
ES513832A0 (es)	1983-08-01	"un procedimiento para la preparacion de fenetilpiperidinas".
ES509526A0 (es)	1983-04-01	Un procedimiento para la preparacion de dihigroimidazoles.
ES510448A0 (es)	1983-04-16	Un procedimiento para la preparacion azaespiroalcanodionas.