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ES480140A1 - Procedure for preparation of derivatives of 3,6,20-trioxo-pregnano. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for preparation of derivatives of 3,6,20-trioxo-pregnano. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES480140A1
ES480140A1 ES480140A ES480140A ES480140A1 ES 480140 A1 ES480140 A1 ES 480140A1 ES 480140 A ES480140 A ES 480140A ES 480140 A ES480140 A ES 480140A ES 480140 A1 ES480140 A1 ES 480140A1
Authority
ES
Spain
Prior art keywords
hydrogen
formula
trioxo
translation
chlorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480140A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD International Holdings GmbH
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/849,563 external-priority patent/US4201778A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of ES480140A1 publication Critical patent/ES480140A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Procedure for the preparation of derivatives of 3, 6, 20-trioxo-pregnane of the general formula I: ** (formula-01) where D A is hydrogen or, provided that Y is (H, betaOH), A can be chlorine; B is hydrogen; X is hydrogen, fluorine, or chlorine; y is (H, BetaOH), or, provided X is chlorine, and can be (H, beta-chlorine); Q is hydroxy or Ov3 where V3 is an acyl radical of a hydrocarbon carboxylic acid that has up to 8 carbon atoms; M is CH2 OV 4, where V4 is hydrogen or an acyl radical of a hydrocarbon carboxylic acid having up to 8 carbon atoms; M is Ch2 Ov4, where V4 is hydrogen or an acyl radical of a hydrocarbon carboxylic acid having up to 8 carbon atoms; or Ov 4 together with Q is an alkylidenedioxy or alkylortoalkanoate group; it is (H, CH3), methylene, (H, alpha0V4) where V4 is as defined above, or together W and Q form an alkylidenedioxy group or grouping. ** (formula-02) ** where R and R1 are lower alkyl; or the grouping ** (formula-03) ** where R2 is lower alkyl or phenyl, characterized in that a compound of the general formula (VII). ** (formula-04) ** oxidizes in position 6. (Machine-translation by Google Translate, not legally binding)
ES480140A 1977-11-08 1979-05-02 Procedure for preparation of derivatives of 3,6,20-trioxo-pregnano. (Machine-translation by Google Translate, not legally binding) Expired ES480140A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/849,563 US4201778A (en) 1977-11-08 1977-11-08 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates
ZA00786054A ZA786054B (en) 1977-11-08 1978-10-26 Novel 6-oxy-genated-3,20-dioxo-pregnane-derivatives,process for the preparation thereof,and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ES480140A1 true ES480140A1 (en) 1980-04-01

Family

ID=27126859

Family Applications (2)

Application Number Title Priority Date Filing Date
ES474745A Expired ES474745A1 (en) 1977-11-08 1978-11-02 PROCEDURE FOR THE PREPARATION OF DERIVATIVES 6-OXYGEN- DOS-3,20-DIOXOPREGNANE
ES480140A Expired ES480140A1 (en) 1977-11-08 1979-05-02 Procedure for preparation of derivatives of 3,6,20-trioxo-pregnano. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES474745A Expired ES474745A1 (en) 1977-11-08 1978-11-02 PROCEDURE FOR THE PREPARATION OF DERIVATIVES 6-OXYGEN- DOS-3,20-DIOXOPREGNANE

Country Status (1)

Country Link
ES (2) ES474745A1 (en)

Also Published As

Publication number Publication date
ES474745A1 (en) 1980-03-01

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