ES472821A1 - Procedimiento para obtener acido 2-amino-2-fenilacetico op- ticamente activo, eventualmente sustituido - Google Patents
Procedimiento para obtener acido 2-amino-2-fenilacetico op- ticamente activo, eventualmente sustituidoInfo
- Publication number
- ES472821A1 ES472821A1 ES472821A ES472821A ES472821A1 ES 472821 A1 ES472821 A1 ES 472821A1 ES 472821 A ES472821 A ES 472821A ES 472821 A ES472821 A ES 472821A ES 472821 A1 ES472821 A1 ES 472821A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- phenyl
- optically active
- unsubstituted
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZGUNAGUHMKGQNY-UHFFFAOYSA-N alpha-phenylglycine Chemical class OC(=O)C(N)C1=CC=CC=C1 ZGUNAGUHMKGQNY-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 2
- 235000011002 L(+)-tartaric acid Nutrition 0.000 abstract 2
- 239000001358 L(+)-tartaric acid Substances 0.000 abstract 2
- FEWJPZIEWOKRBE-LWMBPPNESA-N L-(+)-Tartaric acid Natural products OC(=O)[C@@H](O)[C@H](O)C(O)=O FEWJPZIEWOKRBE-LWMBPPNESA-N 0.000 abstract 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 2
- 230000009466 transformation Effects 0.000 abstract 2
- ZGUNAGUHMKGQNY-ZETCQYMHSA-N L-alpha-phenylglycine zwitterion Chemical compound OC(=O)[C@@H](N)C1=CC=CC=C1 ZGUNAGUHMKGQNY-ZETCQYMHSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001728 carbonyl compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedimiento para obtener ácido 2-amino-2-fenilacético ópticamente activo, eventualmente sustituido, de la fórmula general I **(Fórmula)** en la que R1, R2 y R3 están sustituidos del mismo o distinto modo con hidrógeno, halógeno o grupos hidroxi, alcohilo, acilo o alcoxi; mediante transformación asimétrica de un aminofenilacetonitrilo DL correspondiente con ácido tartárico L.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2738934 | 1977-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES472821A1 true ES472821A1 (es) | 1979-10-01 |
Family
ID=6017605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES472821A Expired ES472821A1 (es) | 1977-08-30 | 1978-08-24 | Procedimiento para obtener acido 2-amino-2-fenilacetico op- ticamente activo, eventualmente sustituido |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4233456A (es) |
| EP (1) | EP0001060B1 (es) |
| JP (1) | JPS5448729A (es) |
| AT (1) | AT364350B (es) |
| BG (1) | BG34033A3 (es) |
| DE (1) | DE2862056D1 (es) |
| ES (1) | ES472821A1 (es) |
| IT (1) | IT1098395B (es) |
| RO (1) | RO76186A (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3002543A1 (de) * | 1980-01-25 | 1981-07-30 | Basf Ag, 6700 Ludwigshafen | 4-tert.-butoxyphenylglycinnitril sowie verfahren zur herstellung von d-(-)- und l-(+)-4-hydroxyphenylglycin |
| US4415504A (en) * | 1981-09-21 | 1983-11-15 | Tanabe Seiyaku Co., Ltd. | p-Hydroxyphenylglycine.α-phenylethanesulfonate, process for production thereof and utilization thereof in resolution of p-hydroxyphenylglycine |
| JPS59170059A (ja) * | 1983-03-16 | 1984-09-26 | Tanabe Seiyaku Co Ltd | 光学活性α―アミノ酸の製法 |
| NL9101380A (nl) * | 1991-08-13 | 1993-03-01 | Dsm Nv | Werkwijze voor de bereiding van een alfa-aminozuur, de overeenkomstige ester en amide. |
| USD399041S (en) | 1996-06-06 | 1998-10-06 | Nike, Inc. | Portion of a shoe outsole |
| EP1352894A1 (en) | 2002-04-09 | 2003-10-15 | DSM IP Assets B.V. | Process for the preparation of enantiomerically enriched compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3385852A (en) * | 1963-05-14 | 1968-05-28 | Angeli Inst Spa | Alpha-substituted 1-naphthylacetic acids |
| DE1543832B2 (de) * | 1965-06-04 | 1977-05-18 | Röhm GmbH, 6100 Darmstadt | Verfahren zur herstellung von alpha-aminocarbonsaeuren |
| US3422132A (en) * | 1966-03-15 | 1969-01-14 | Du Pont | Preparation of primary alpha-aminonitriles |
| GB1389217A (en) * | 1971-06-02 | 1975-04-03 | Glaxo Lab Ltd | Phenylglycine derivatives |
| US3808254A (en) * | 1971-06-10 | 1974-04-30 | Syntex Corp | Resolution-racemization of alpha-amino-alpha-phenylacetonitrile |
| BE795874A (fr) * | 1972-02-25 | 1973-08-23 | Glaxo Lab Ltd | Procede de preparation d'esters optiquement actifs d'alpha-amino-acides |
| HU165026B (es) * | 1972-08-11 | 1974-06-28 | ||
| US3832388A (en) * | 1972-09-07 | 1974-08-27 | R Lorenz | Resolution of 2-(p-hydroxy)phenylglycine |
| NL7514300A (nl) * | 1975-12-09 | 1977-06-13 | Stamicarbon | Werkwijze voor de bereiding van optisch actief fenylglycineamide. |
| US4072698A (en) * | 1976-12-02 | 1978-02-07 | The Upjohn Company | Resolution of aminonitriles |
-
1978
- 1978-08-17 EP EP78100684A patent/EP0001060B1/de not_active Expired
- 1978-08-17 DE DE7878100684T patent/DE2862056D1/de not_active Expired
- 1978-08-24 ES ES472821A patent/ES472821A1/es not_active Expired
- 1978-08-25 BG BG040744A patent/BG34033A3/xx unknown
- 1978-08-26 RO RO7895045A patent/RO76186A/ro unknown
- 1978-08-28 IT IT27076/78A patent/IT1098395B/it active
- 1978-08-28 AT AT0623478A patent/AT364350B/de not_active IP Right Cessation
- 1978-08-28 US US05/937,093 patent/US4233456A/en not_active Expired - Lifetime
- 1978-08-29 JP JP10447878A patent/JPS5448729A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATA623478A (de) | 1981-03-15 |
| EP0001060A1 (de) | 1979-03-21 |
| BG34033A3 (en) | 1983-06-15 |
| IT7827076A0 (it) | 1978-08-28 |
| AT364350B (de) | 1981-10-12 |
| RO76186A (ro) | 1981-08-17 |
| US4233456A (en) | 1980-11-11 |
| IT1098395B (it) | 1985-09-07 |
| DE2862056D1 (en) | 1982-11-11 |
| JPS5448729A (en) | 1979-04-17 |
| EP0001060B1 (de) | 1982-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970925 |