ES478073A1 - (Cycloalkyl)-alkylbenzamides - Google Patents
(Cycloalkyl)-alkylbenzamidesInfo
- Publication number
- ES478073A1 ES478073A1 ES478073A ES478073A ES478073A1 ES 478073 A1 ES478073 A1 ES 478073A1 ES 478073 A ES478073 A ES 478073A ES 478073 A ES478073 A ES 478073A ES 478073 A1 ES478073 A1 ES 478073A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- alkylbenzamides
- cycloalkyl
- benzamides
- racemates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000753 cycloalkyl group Chemical group 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940054066 benzamide antipsychotics Drugs 0.000 abstract 1
- 150000003936 benzamides Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Abstract
Benzamides, in the form of racemates or enantiomers, corresponding to the formula (I> < IMAGE > in which n and m are independently of one another equal to 1, 2, 3 or 4 and R is the radical CF3 or an alkylthio radical in which the alkyl is linear or branched and has from 1 to 6 carbon atoms, and also their addition salts with pharmaceutically acceptable acids. The compounds are useful in treating disorders of the central nervous system, and a process for preparing them and pharmaceutical compositions containing them are also disclosed.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7805580A FR2418226A1 (en) | 1978-02-27 | 1978-02-27 | METHOXY-2 ALKYLTHIO-5 BENZAMIDES AND THEIR THERAPEUTIC APPLICATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES478073A1 true ES478073A1 (en) | 1979-05-16 |
Family
ID=9205110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478073A Expired ES478073A1 (en) | 1978-02-27 | 1979-02-26 | (Cycloalkyl)-alkylbenzamides |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS54122269A (en) |
| AT (1) | AT373581B (en) |
| AU (1) | AU521854B2 (en) |
| BE (1) | BE874490A (en) |
| CA (1) | CA1105937A (en) |
| CH (1) | CH637378A5 (en) |
| DE (1) | DE2907377A1 (en) |
| DK (1) | DK82379A (en) |
| ES (1) | ES478073A1 (en) |
| FI (1) | FI790658A7 (en) |
| FR (1) | FR2418226A1 (en) |
| GB (1) | GB2014995B (en) |
| GR (1) | GR66973B (en) |
| IE (1) | IE47897B1 (en) |
| IL (1) | IL56747A0 (en) |
| IT (1) | IT1114210B (en) |
| LU (1) | LU80976A1 (en) |
| NL (1) | NL7901472A (en) |
| NO (1) | NO790648L (en) |
| NZ (1) | NZ189771A (en) |
| PT (1) | PT69290A (en) |
| SE (1) | SE430501B (en) |
| ZA (1) | ZA799808B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT50889A (en) * | 1987-05-25 | 1990-03-28 | Foreshore Protection Pty Ltd | Anti-erosion cover |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2245628B1 (en) * | 1973-09-28 | 1977-03-11 | Ile De France |
-
1978
- 1978-02-27 FR FR7805580A patent/FR2418226A1/en active Granted
-
1979
- 1979-02-26 PT PT69290A patent/PT69290A/en unknown
- 1979-02-26 CH CH188379A patent/CH637378A5/en not_active IP Right Cessation
- 1979-02-26 ES ES478073A patent/ES478073A1/en not_active Expired
- 1979-02-26 ZA ZA00799808A patent/ZA799808B/en unknown
- 1979-02-26 CA CA322,283A patent/CA1105937A/en not_active Expired
- 1979-02-26 NL NL7901472A patent/NL7901472A/en not_active Application Discontinuation
- 1979-02-26 JP JP2247679A patent/JPS54122269A/en active Pending
- 1979-02-26 NO NO790648A patent/NO790648L/en unknown
- 1979-02-26 DK DK82379A patent/DK82379A/en not_active Application Discontinuation
- 1979-02-26 NZ NZ189771A patent/NZ189771A/en unknown
- 1979-02-26 DE DE19792907377 patent/DE2907377A1/en not_active Withdrawn
- 1979-02-26 AU AU44604/79A patent/AU521854B2/en not_active Ceased
- 1979-02-26 IT IT20542/79A patent/IT1114210B/en active
- 1979-02-26 SE SE7901708A patent/SE430501B/en unknown
- 1979-02-27 FI FI790658A patent/FI790658A7/en not_active Application Discontinuation
- 1979-02-27 GB GB7906954A patent/GB2014995B/en not_active Expired
- 1979-02-27 BE BE0/193730A patent/BE874490A/en not_active IP Right Cessation
- 1979-02-27 IL IL56747A patent/IL56747A0/en unknown
- 1979-02-27 LU LU80976A patent/LU80976A1/en unknown
- 1979-02-27 GR GR58492A patent/GR66973B/el unknown
- 1979-02-27 AT AT0149479A patent/AT373581B/en not_active IP Right Cessation
- 1979-08-08 IE IE558/79A patent/IE47897B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2418226A1 (en) | 1979-09-21 |
| JPS54122269A (en) | 1979-09-21 |
| IE790558L (en) | 1979-08-27 |
| SE430501B (en) | 1983-11-21 |
| LU80976A1 (en) | 1980-09-24 |
| FI790658A7 (en) | 1979-08-28 |
| NL7901472A (en) | 1979-08-29 |
| AT373581B (en) | 1984-02-10 |
| AU4460479A (en) | 1979-09-06 |
| DK82379A (en) | 1979-08-28 |
| CA1105937A (en) | 1981-07-28 |
| CH637378A5 (en) | 1983-07-29 |
| IE47897B1 (en) | 1984-07-11 |
| FR2418226B1 (en) | 1980-11-07 |
| IL56747A0 (en) | 1979-05-31 |
| IT1114210B (en) | 1986-01-27 |
| ATA149479A (en) | 1983-06-15 |
| SE7901708L (en) | 1979-08-28 |
| DE2907377A1 (en) | 1979-09-06 |
| PT69290A (en) | 1979-03-01 |
| GR66973B (en) | 1981-05-15 |
| GB2014995A (en) | 1979-09-05 |
| NO790648L (en) | 1979-08-28 |
| GB2014995B (en) | 1982-07-28 |
| NZ189771A (en) | 1980-11-14 |
| IT7920542A0 (en) | 1979-02-26 |
| ZA799808B (en) | 1980-06-25 |
| BE874490A (en) | 1979-08-27 |
| AU521854B2 (en) | 1982-05-06 |
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