ES475559A1 - Procedimiento para la preparacion de derivados de tiazolidi-na. - Google Patents
Procedimiento para la preparacion de derivados de tiazolidi-na.Info
- Publication number
- ES475559A1 ES475559A1 ES475559A ES475559A ES475559A1 ES 475559 A1 ES475559 A1 ES 475559A1 ES 475559 A ES475559 A ES 475559A ES 475559 A ES475559 A ES 475559A ES 475559 A1 ES475559 A1 ES 475559A1
- Authority
- ES
- Spain
- Prior art keywords
- salidiuretic
- salidiuresis
- effecting
- employing
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000000054 salidiuretic effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 150000003548 thiazolidines Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Procedimiento para la preparación de derivados de tiazolidina de la fórmula general I *** ver imagen 01 en donde R1 significa alcohilo o alquenilo inferior de 1 a 4 átomos de carbono o un radical piridilmetilo; R2 y R3 significan hidrógeno o alcohilo de 1 a 3 átomos de carbono; R4 y R6 significan hidrógeno o halógeno, pero representando hidrógeno uno de los radicales R4 o R6; R3 y R4 pueden estar unidos también entre sí cíclicamente a través de una cadena metilénica recta o ramificada de 1 a 5 átomos de carbono; R5 significa hidrógeno, alcohilo inferior de 1 a 4 átomos de carbono o bencilo, pudiendo el anillo aromático del radical bencílico estar sustituido también con cloro o metilo; Y significa halógeno y Z significa oxígeno o azufre.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762601791 DE2601791A1 (de) | 1976-01-20 | 1976-01-20 | Thiazolidinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES475559A1 true ES475559A1 (es) | 1979-05-01 |
Family
ID=5967727
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES455013A Expired ES455013A1 (es) | 1976-01-20 | 1977-01-14 | Procedimiento para la preparacion de derivados detiazolidina |
| ES475558A Expired ES475558A1 (es) | 1976-01-20 | 1978-11-30 | Procedimiento para la preparacion de derivados de tiazolidi-na. |
| ES475559A Expired ES475559A1 (es) | 1976-01-20 | 1978-11-30 | Procedimiento para la preparacion de derivados de tiazolidi-na. |
| ES475557A Expired ES475557A1 (es) | 1976-01-20 | 1978-11-30 | Procedimiento para la preparacion de derivados de tiazolidi-na. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES455013A Expired ES455013A1 (es) | 1976-01-20 | 1977-01-14 | Procedimiento para la preparacion de derivados detiazolidina |
| ES475558A Expired ES475558A1 (es) | 1976-01-20 | 1978-11-30 | Procedimiento para la preparacion de derivados de tiazolidi-na. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475557A Expired ES475557A1 (es) | 1976-01-20 | 1978-11-30 | Procedimiento para la preparacion de derivados de tiazolidi-na. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4129656A (es) |
| JP (1) | JPS5289669A (es) |
| AT (1) | AT356102B (es) |
| AU (1) | AU511547B2 (es) |
| BE (1) | BE850575A (es) |
| CA (1) | CA1078847A (es) |
| DE (1) | DE2601791A1 (es) |
| DK (1) | DK19777A (es) |
| ES (4) | ES455013A1 (es) |
| FI (1) | FI770142A7 (es) |
| FR (1) | FR2338937A1 (es) |
| GB (1) | GB1541974A (es) |
| HU (1) | HU175096B (es) |
| IE (1) | IE44213B1 (es) |
| IL (1) | IL51287A (es) |
| IT (1) | IT1077590B (es) |
| LU (1) | LU76597A1 (es) |
| NL (1) | NL7700381A (es) |
| NO (1) | NO770161L (es) |
| SE (1) | SE7700500L (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2737195A1 (de) * | 1977-08-18 | 1979-03-01 | Hoechst Ag | Benzolsulfonamidderivate und verfahren zu ihrer herstellung |
| DE19731782A1 (de) * | 1997-07-24 | 1999-01-28 | Bayer Ag | Verfahren zur Herstellung von Pyridylmethylisocyanaten |
| DE19908539A1 (de) * | 1999-02-26 | 2000-08-31 | Aventis Pharma Gmbh | Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10008274A1 (de) * | 2000-02-23 | 2001-08-30 | Aventis Pharma Gmbh | Substituierte 8,8a-Dihydro-3aH-indeno[1,2-d]thiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| DE10142665B4 (de) * | 2001-08-31 | 2004-05-06 | Aventis Pharma Deutschland Gmbh | C2-Disubstituierte Indan-1-one und ihre Derivate |
| DE10142722A1 (de) * | 2001-08-31 | 2003-03-27 | Aventis Pharma Deutschland GmbH, 65929 Frankfurt | C2-substituierte Indan-1-one und ihre Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US7271195B2 (en) * | 2003-06-10 | 2007-09-18 | Kalypsys, Inc. | Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease |
| AU2004247136A1 (en) * | 2003-06-10 | 2004-12-23 | Kalypsys, Inc. | Carbonyl compounds as inhibitors of histone deacetylase for the treatment of disease |
| AU2005251816A1 (en) * | 2004-06-10 | 2005-12-22 | Kalypsys, Inc. | Novel sulfonamides as inhibitors of histone deacetylase for the treatment of disease |
| EP1960343B1 (en) * | 2005-11-08 | 2012-04-04 | Laboratorios del Dr. Esteve S.A. | Indene derivatives, their preparation and use as medicaments |
| EP1884515A1 (en) * | 2006-07-31 | 2008-02-06 | Laboratorios del Dr. Esteve S.A. | Substituted indanyl sulfonamide compounds, their preparation and use as medicaments |
| CA2955582C (en) | 2014-07-18 | 2021-03-16 | Ohio University | Imidazole and thiazole compositions for modifying biological signaling |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3671534A (en) * | 1970-03-16 | 1972-06-20 | Sandoz Ag | 6,6-DI-LOWER ALKYL-2,3,5,6-TETRAHYDROIMIDAZO {8 2,1-b{9 {11 THIAZOLES |
| DE2546165A1 (de) * | 1975-10-15 | 1977-04-28 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
-
0
- SE SE7700500A patent/SE7700500L/xx unknown
-
1976
- 1976-01-20 DE DE19762601791 patent/DE2601791A1/de not_active Withdrawn
-
1977
- 1977-01-14 ES ES455013A patent/ES455013A1/es not_active Expired
- 1977-01-14 NL NL7700381A patent/NL7700381A/xx not_active Application Discontinuation
- 1977-01-18 FI FI770142A patent/FI770142A7/fi not_active Application Discontinuation
- 1977-01-18 US US05/760,411 patent/US4129656A/en not_active Expired - Lifetime
- 1977-01-18 IL IL51287A patent/IL51287A/xx unknown
- 1977-01-18 IT IT19413/77A patent/IT1077590B/it active
- 1977-01-18 LU LU76597A patent/LU76597A1/xx unknown
- 1977-01-19 AU AU21433/77A patent/AU511547B2/en not_active Expired
- 1977-01-19 CA CA270,057A patent/CA1078847A/en not_active Expired
- 1977-01-19 NO NO770161A patent/NO770161L/no unknown
- 1977-01-19 IE IE98/77A patent/IE44213B1/en unknown
- 1977-01-19 AT AT28277A patent/AT356102B/de not_active IP Right Cessation
- 1977-01-19 DK DK19777A patent/DK19777A/da unknown
- 1977-01-20 BE BE174240A patent/BE850575A/xx unknown
- 1977-01-20 GB GB772315A patent/GB1541974A/en not_active Expired
- 1977-01-20 HU HU77HO1953A patent/HU175096B/hu unknown
- 1977-01-20 JP JP448377A patent/JPS5289669A/ja active Pending
- 1977-01-20 FR FR7701519A patent/FR2338937A1/fr active Granted
-
1978
- 1978-11-30 ES ES475558A patent/ES475558A1/es not_active Expired
- 1978-11-30 ES ES475559A patent/ES475559A1/es not_active Expired
- 1978-11-30 ES ES475557A patent/ES475557A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IL51287A0 (en) | 1977-03-31 |
| JPS5289669A (en) | 1977-07-27 |
| SE7700500L (sv) | 1977-07-21 |
| NL7700381A (nl) | 1977-07-22 |
| IL51287A (en) | 1980-05-30 |
| ES475557A1 (es) | 1979-05-01 |
| AT356102B (de) | 1980-04-10 |
| AU2143377A (en) | 1978-07-27 |
| ATA28277A (de) | 1979-09-15 |
| IE44213L (en) | 1977-07-20 |
| CA1078847A (en) | 1980-06-03 |
| FR2338937A1 (fr) | 1977-08-19 |
| DK19777A (da) | 1977-07-21 |
| ES475558A1 (es) | 1979-05-16 |
| GB1541974A (en) | 1979-03-14 |
| US4129656A (en) | 1978-12-12 |
| FR2338937B1 (es) | 1980-03-28 |
| BE850575A (fr) | 1977-07-20 |
| IE44213B1 (en) | 1981-09-09 |
| IT1077590B (it) | 1985-05-04 |
| FI770142A7 (es) | 1977-07-21 |
| HU175096B (hu) | 1980-05-28 |
| DE2601791A1 (de) | 1977-07-21 |
| ES455013A1 (es) | 1979-05-01 |
| NO770161L (no) | 1977-07-21 |
| LU76597A1 (es) | 1977-07-27 |
| AU511547B2 (en) | 1980-08-21 |
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