ES475028A1 - Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5- (2h,4h)-dionas - Google Patents
Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5- (2h,4h)-dionasInfo
- Publication number
- ES475028A1 ES475028A1 ES475028A ES475028A ES475028A1 ES 475028 A1 ES475028 A1 ES 475028A1 ES 475028 A ES475028 A ES 475028A ES 475028 A ES475028 A ES 475028A ES 475028 A1 ES475028 A1 ES 475028A1
- Authority
- ES
- Spain
- Prior art keywords
- diones
- triazine
- phenyl
- substituted
- agents containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003224 coccidiostatic agent Chemical class 0.000 title abstract 2
- XGPCOQNUQVZURR-UHFFFAOYSA-N 2-phenyl-1,2,4-triazine-3,5-dione Chemical class O=C1NC(=O)C=NN1C1=CC=CC=C1 XGPCOQNUQVZURR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Containers Having Bodies Formed In One Piece (AREA)
- Fodder In General (AREA)
Abstract
1. Procedimiento para prepara 2-femil-1,2,4-triazin-3,5- (2H,4H)-dionas sustituidas de la fórmula general I, **(Fórmula-01)** en la que R1 y R2, independientemente entre sí, significan hidrógeno, un radical alcohilo de cadena recta o ramificado, con 1 hasta 4 átomos de carbono, R3 y R4, independientemente entre sí, significan hidrógeno o halógeno, Z significa oxígeno, azufre, el grupo sulfóxido o el grupo sulfona, m significa las cifras 0, 1 ó 2, y n significa 0 ó 1, así como sus sales de metales alcalinos, alcolinotérreos o amónicas, caracterizado porque con el fin de separar agua se calienta un compuesto de la fórmula general III ** (Fórmula-03)** en la que los sustituyentes e índices tienen los mismos significados que en la fórmula I, a temperaturas comprendidas entre 50 y 150ºC, durante 2 a 8 horas, con adición de cantidades por lo menos equivalentes de sustancias básicas, tales como hidróxido de sodio, trietilamina, piridina, metilpiridina o acetato de sodio, o de sustancias ácidas, tales como anhídrido de ácido acético o acido polifosfórico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772722537 DE2722537A1 (de) | 1977-05-18 | 1977-05-18 | Substituierte 2-phenyl-1,2,4-triazin-3,5-(2h,4h)-dione, verfahren zu ihrer herstellung und sie enthaltende coccidiostatische mittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES475028A1 true ES475028A1 (es) | 1980-08-16 |
Family
ID=6009346
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469714A Expired ES469714A1 (es) | 1977-05-18 | 1978-05-11 | Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5- (2h,4h)-dionas |
| ES475028A Expired ES475028A1 (es) | 1977-05-18 | 1978-11-13 | Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5- (2h,4h)-dionas |
| ES475029A Expired ES475029A1 (es) | 1977-05-18 | 1978-11-13 | Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5-(2h,- 4h)-dionas. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469714A Expired ES469714A1 (es) | 1977-05-18 | 1978-05-11 | Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5- (2h,4h)-dionas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475029A Expired ES475029A1 (es) | 1977-05-18 | 1978-11-13 | Procedimiento para preparar 2-fenil-1,2,4-triazin-3,5-(2h,- 4h)-dionas. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4198407A (es) |
| JP (1) | JPS5416492A (es) |
| BE (1) | BE867210A (es) |
| DE (1) | DE2722537A1 (es) |
| ES (3) | ES469714A1 (es) |
| FR (1) | FR2391203A1 (es) |
| GB (1) | GB1586413A (es) |
| IT (1) | IT1096216B (es) |
| NL (1) | NL7805270A (es) |
| ZA (1) | ZA782817B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1600840A (en) * | 1978-05-30 | 1981-10-21 | Wellcome Found | Diphenylether derivatives useful as flukicidal agents |
| DE3408924A1 (de) * | 1984-03-12 | 1985-09-26 | Hoechst Ag, 6230 Frankfurt | Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| WO1986000072A1 (en) * | 1984-06-12 | 1986-01-03 | Fmc Corporation | Herbicidal 2-aryl-1,2,4-triazine-3,5(2h,4h)-diones and sulfur analogs thereof |
| DE3531919A1 (de) * | 1985-09-07 | 1987-03-19 | Hoechst Ag | Substituierte 2-phenyl-hexahydro-1,2,4-triazin-3,5-dione, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| DE3805660A1 (de) * | 1988-02-24 | 1989-09-07 | Bayer Ag | Substituierte 1,2,4-triazindione, verfahren zu ihrer herstellung und ihre verwendung |
| US4956004A (en) * | 1989-05-10 | 1990-09-11 | Fmc Corporation | Herbicidal triazinediones |
| US4985065A (en) * | 1989-05-10 | 1991-01-15 | Fmc Corporation | Tetrazolinone herbicides |
| DE4120138A1 (de) * | 1991-06-19 | 1992-12-24 | Bayer Ag | Substituierte hexahydro-1,2,4-triazindione, verfahren zu ihrer herstellung, zwischenprodukte dafuer und ihre verwendung |
| EP0476439A1 (de) * | 1990-09-18 | 1992-03-25 | Bayer Ag | Substituierte 1,2,4-Triazindione, Verfahren zu ihrer Herstellung, Zwischenprodukte dafür und ihre Verwendung |
| DE4427529A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Verfahren zur Herstellung von 1,2,4-Triazin-3,5-dionen |
| US5595807A (en) * | 1995-06-01 | 1997-01-21 | Gooding, Jr.; Robert B. | Combination wet dry wipe |
| US6787652B1 (en) | 1999-09-30 | 2004-09-07 | Pfizer, Inc. | 6-Azauracil derivatives as thyroid receptor ligands |
| CN107459493B (zh) * | 2016-06-02 | 2019-11-01 | 华中师范大学 | 地克珠利衍生物及其应用和含有该衍生物的杀菌剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3912723A (en) * | 1971-03-29 | 1975-10-14 | Pfizer | 2-Phenyl-as-triazine-3,5(2H,4H)diones |
| US3896124A (en) * | 1971-07-07 | 1975-07-22 | Pfizer | Preparation of 2 (aryl)-as-triazine-3,5(2h,4h)-diones |
| GB1448696A (en) * | 1973-05-29 | 1976-09-08 | Pfizer | 2-phqnyl-astriazine-3,4-2h,4h-diones |
| US3882115A (en) * | 1973-06-25 | 1975-05-06 | Pfizer | Preparation of 2-aryl-as-triazine-3,5 (2H,4H)-diones |
| US3883527A (en) * | 1973-10-19 | 1975-05-13 | Pfizer | Process for preparation of 2-aryl-1,3,4-triazine-3,5(2H,4H)-diones |
| US3883528A (en) * | 1974-04-19 | 1975-05-13 | Pfizer | Preparation of 2(aryl)-as-triazine-3,5(2H,4H)-dione coccidiostats |
-
1977
- 1977-05-18 DE DE19772722537 patent/DE2722537A1/de active Pending
-
1978
- 1978-05-11 ES ES469714A patent/ES469714A1/es not_active Expired
- 1978-05-16 NL NL7805270A patent/NL7805270A/xx not_active Application Discontinuation
- 1978-05-16 US US05/906,638 patent/US4198407A/en not_active Expired - Lifetime
- 1978-05-16 GB GB19810/78A patent/GB1586413A/en not_active Expired
- 1978-05-16 IT IT23454/78A patent/IT1096216B/it active
- 1978-05-17 ZA ZA00782817A patent/ZA782817B/xx unknown
- 1978-05-18 JP JP5832878A patent/JPS5416492A/ja active Pending
- 1978-05-18 BE BE187808A patent/BE867210A/xx unknown
- 1978-05-18 FR FR7814783A patent/FR2391203A1/fr active Granted
- 1978-11-13 ES ES475028A patent/ES475028A1/es not_active Expired
- 1978-11-13 ES ES475029A patent/ES475029A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL7805270A (nl) | 1978-11-21 |
| FR2391203B1 (es) | 1980-06-20 |
| BE867210A (fr) | 1978-11-20 |
| IT1096216B (it) | 1985-08-26 |
| DE2722537A1 (de) | 1978-11-23 |
| GB1586413A (en) | 1981-03-18 |
| ES469714A1 (es) | 1980-01-01 |
| US4198407A (en) | 1980-04-15 |
| FR2391203A1 (fr) | 1978-12-15 |
| ES475029A1 (es) | 1979-05-16 |
| ZA782817B (en) | 1979-05-30 |
| JPS5416492A (en) | 1979-02-07 |
| IT7823454A0 (it) | 1978-05-16 |
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