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ES463456A1 - Procedimiento para la obtencion de garamina y derivados de garamina. - Google Patents

Procedimiento para la obtencion de garamina y derivados de garamina.

Info

Publication number
ES463456A1
ES463456A1 ES463456A ES463456A ES463456A1 ES 463456 A1 ES463456 A1 ES 463456A1 ES 463456 A ES463456 A ES 463456A ES 463456 A ES463456 A ES 463456A ES 463456 A1 ES463456 A1 ES 463456A1
Authority
ES
Spain
Prior art keywords
garamine
preparation
derivatives
formula
radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES463456A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES463456A1 publication Critical patent/ES463456A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para la obtención de garamina y derivados de garamina de fórmula general I ***(ver fórmula) donde los restos R1, en cada caso significan H o grupos protectores amino y los restos R2, en cada caso, significan H ó grupos protectores hidroxi, por disociación selectiva de derivados funcionales de antibióticos de sacáridos que contienen la unidad garamina, con ácidos fuertes.
ES463456A 1976-10-22 1977-10-21 Procedimiento para la obtencion de garamina y derivados de garamina. Expired ES463456A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762647807 DE2647807A1 (de) 1976-10-22 1976-10-22 Verfahren zur herstellung von garamin und garaminderivaten

Publications (1)

Publication Number Publication Date
ES463456A1 true ES463456A1 (es) 1978-11-16

Family

ID=5991121

Family Applications (1)

Application Number Title Priority Date Filing Date
ES463456A Expired ES463456A1 (es) 1976-10-22 1977-10-21 Procedimiento para la obtencion de garamina y derivados de garamina.

Country Status (8)

Country Link
US (1) US4218561A (es)
JP (1) JPS5353643A (es)
DE (1) DE2647807A1 (es)
ES (1) ES463456A1 (es)
FR (1) FR2368498A1 (es)
GB (1) GB1571454A (es)
HU (1) HU177869B (es)
IT (1) IT1091102B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942547A (en) * 1995-09-08 1999-08-24 Scriptgen Pharmaceuticals, Inc. 2-Deoxystreptamine derivatives, pharmaceutical compositions thereof and therapeutic methods using same

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4063015A (en) * 1973-08-27 1977-12-13 Schering Corporation Garamine and derivatives thereof
US4000261A (en) * 1974-11-29 1976-12-28 Schering Corporation 5-epi-4,6-di-o-(aminoglycosyl)-2-deoxystreptamines, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor

Also Published As

Publication number Publication date
IT1091102B (it) 1985-06-26
GB1571454A (en) 1980-07-16
FR2368498A1 (fr) 1978-05-19
US4218561A (en) 1980-08-19
HU177869B (en) 1982-01-28
FR2368498B1 (es) 1981-01-09
JPS5353643A (en) 1978-05-16
DE2647807A1 (de) 1978-04-27

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