ES462648A1 - Procedimiento para la obtencion de metilen-bis-quinazolinas. - Google Patents
Procedimiento para la obtencion de metilen-bis-quinazolinas.Info
- Publication number
- ES462648A1 ES462648A1 ES462648A ES462648A ES462648A1 ES 462648 A1 ES462648 A1 ES 462648A1 ES 462648 A ES462648 A ES 462648A ES 462648 A ES462648 A ES 462648A ES 462648 A1 ES462648 A1 ES 462648A1
- Authority
- ES
- Spain
- Prior art keywords
- denotes
- quinazolinone
- moieties
- azo dyes
- heterocyclic azo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000049 pigment Substances 0.000 title abstract 2
- QMNUDYFKZYBWQX-UHFFFAOYSA-N 1H-quinazolin-4-one Chemical group C1=CC=C2C(=O)N=CNC2=C1 QMNUDYFKZYBWQX-UHFFFAOYSA-N 0.000 title 1
- 239000000987 azo dye Substances 0.000 title 1
- 125000000623 heterocyclic group Chemical group 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical group OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B29/00—Monoazo dyes prepared by diazotising and coupling
- C09B29/0018—Monoazo dyes prepared by diazotising and coupling from diazotized aminopolycyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B29/00—Monoazo dyes prepared by diazotising and coupling
- C09B29/0025—Monoazo dyes prepared by diazotising and coupling from diazotized amino heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B29/00—Monoazo dyes prepared by diazotising and coupling
- C09B29/32—Monoazo dyes prepared by diazotising and coupling from coupling components containing a reactive methylene group
- C09B29/325—Monoazo dyes prepared by diazotising and coupling from coupling components containing a reactive methylene group free of acid groups
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B31/00—Disazo and polyazo dyes of the type A->B->C, A->B->C->D, or the like, prepared by diazotising and coupling
- C09B31/02—Disazo dyes
- C09B31/10—Disazo dyes from a coupling component "C" containing reactive methylene groups
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B35/00—Disazo and polyazo dyes of the type A<-D->B prepared by diazotising and coupling
- C09B35/02—Disazo dyes
- C09B35/021—Disazo dyes characterised by two coupling components of the same type
- C09B35/035—Disazo dyes characterised by two coupling components of the same type in which the coupling component containing an activated methylene group
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Coloring (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedimiento para la obtención de metilenbis-quinazolinonas de fórmula ***(ver fórmula I) donde R1 significa hidrógeno, C1-C4-alquilo o ambos R1 juntos significan CO, R2 significa un sustituyente y n representa 0, 1,2, 3 ó 4, caracterizado porque derivados funcionales del ácido masónico se hacen reaccionar con amidas de ácido antranílico de fórmula *** (ver fórmula II)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2644265A DE2644265C2 (de) | 1976-09-30 | 1976-09-30 | Chinazoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462648A1 true ES462648A1 (es) | 1978-06-16 |
Family
ID=5989378
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462648A Expired ES462648A1 (es) | 1976-09-30 | 1977-09-26 | Procedimiento para la obtencion de metilen-bis-quinazolinas. |
| ES462758A Expired ES462758A1 (es) | 1976-09-30 | 1977-09-29 | Procedimiento para la obtencion de pigmentos azoicos. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462758A Expired ES462758A1 (es) | 1976-09-30 | 1977-09-29 | Procedimiento para la obtencion de pigmentos azoicos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4225489A (es) |
| JP (2) | JPS603302B2 (es) |
| BE (1) | BE859180A (es) |
| BR (1) | BR7706506A (es) |
| CH (1) | CH634070A5 (es) |
| DE (1) | DE2644265C2 (es) |
| DK (1) | DK430577A (es) |
| ES (2) | ES462648A1 (es) |
| FR (1) | FR2366337A1 (es) |
| GB (1) | GB1554057A (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2812635A1 (de) * | 1978-03-22 | 1979-09-27 | Bayer Ag | Heterocyclische verbindungen |
| US4625027A (en) * | 1982-10-25 | 1986-11-25 | Ciba-Geigy Corporation | Bisquinazolines useful in color former systems |
| US4526913A (en) * | 1984-01-13 | 1985-07-02 | J. H. Diamond Company | Dimer polymeric coating selectively strippable as cohesive film |
| US6667300B2 (en) | 2000-04-25 | 2003-12-23 | Icos Corporation | Inhibitors of human phosphatidylinositol 3-kinase delta |
| NZ522076A (en) * | 2000-04-25 | 2005-08-26 | Icos Corp | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
| CA2477088A1 (en) | 2002-02-22 | 2003-10-02 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| US20050043239A1 (en) * | 2003-08-14 | 2005-02-24 | Jason Douangpanya | Methods of inhibiting immune responses stimulated by an endogenous factor |
| US20050054614A1 (en) * | 2003-08-14 | 2005-03-10 | Diacovo Thomas G. | Methods of inhibiting leukocyte accumulation |
| RS55551B1 (sr) | 2004-05-13 | 2017-05-31 | Icos Corp | Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta |
| JP2008500338A (ja) * | 2004-05-25 | 2008-01-10 | イコス・コーポレイション | 造血細胞の異常増殖を治療及び/又は予防する方法 |
| AU2006214190A1 (en) * | 2005-02-17 | 2006-08-24 | Icos Corporation | Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation |
| US9492449B2 (en) | 2008-11-13 | 2016-11-15 | Gilead Calistoga Llc | Therapies for hematologic malignancies |
| CN102271683B (zh) | 2008-11-13 | 2014-07-09 | 吉里德卡利斯托加公司 | 恶性血液病的治疗 |
| CA2756347A1 (en) | 2009-03-24 | 2010-09-30 | Gilead Calistoga Llc | Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives and methods of use |
| CA2759724A1 (en) * | 2009-04-20 | 2010-10-28 | Calistoga Pharmaceuticals, Inc. | Methods of treatment for solid tumors |
| CA2768843A1 (en) | 2009-07-21 | 2011-01-27 | Gilead Calistoga Llc | Treatment of liver disorders with pi3k inhibitors |
| AR090253A1 (es) | 2012-03-05 | 2014-10-29 | Gilead Calistoga Llc | Formas polimorficas de (s)-2-(1-(9h-purin-6-ilamino)propil)-5-fluor-3-fenilquinazolin-4(3h)-ona |
| JP2017500319A (ja) | 2013-12-20 | 2017-01-05 | ギリアード カリストガ エルエルシー | (s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態 |
| MX2016008259A (es) | 2013-12-20 | 2016-10-13 | Gilead Calistoga Llc | Metodo de proceso para inhibidores de fosfatidilinositol 3-cinasa. |
| AU2015274696B2 (en) | 2014-06-13 | 2018-09-27 | Gilead Sciences, Inc. | Phosphatidylinositol 3-kinase inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA781761A (en) * | 1968-04-02 | F. Van Brocklin Owen | Inflator means for tires and the like | |
| US1032734A (en) * | 1909-04-22 | 1912-07-16 | Marston Taylor Bogert | Products obtainable from 4,6-diamino-1.3-xylene and process of making. |
| US3382228A (en) | 1965-05-03 | 1968-05-07 | Interchem Corp | Process for preparing azomalonanilide pigments |
| JPS5117954B2 (es) * | 1971-08-24 | 1976-06-05 | ||
| DE2219169C3 (de) * | 1972-04-20 | 1978-08-24 | Basf Ag, 6700 Ludwigshafen | Chinazolon-Monoazopigmente, deren Herstellung und Verwendung zum Färben von Druckfarben, Lacken, Kunststoffen oder Gummi |
| DE2245093A1 (de) * | 1972-09-14 | 1974-03-21 | Basf Ag | Wasserloesliche azofarbstoffe der pyrimido-bis-benzimidazolreihe |
-
1976
- 1976-09-30 DE DE2644265A patent/DE2644265C2/de not_active Expired
-
1977
- 1977-09-26 ES ES462648A patent/ES462648A1/es not_active Expired
- 1977-09-27 CH CH1181277A patent/CH634070A5/de not_active IP Right Cessation
- 1977-09-27 GB GB40151/77A patent/GB1554057A/en not_active Expired
- 1977-09-28 US US05/837,404 patent/US4225489A/en not_active Expired - Lifetime
- 1977-09-28 JP JP52115688A patent/JPS603302B2/ja not_active Expired
- 1977-09-29 BR BR7706506A patent/BR7706506A/pt unknown
- 1977-09-29 FR FR7729355A patent/FR2366337A1/fr active Granted
- 1977-09-29 BE BE181289A patent/BE859180A/xx unknown
- 1977-09-29 DK DK430577A patent/DK430577A/da unknown
- 1977-09-29 ES ES462758A patent/ES462758A1/es not_active Expired
-
1980
- 1980-11-27 JP JP55165962A patent/JPS6038421B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS603302B2 (ja) | 1985-01-26 |
| FR2366337B1 (es) | 1984-03-09 |
| JPS5344581A (en) | 1978-04-21 |
| ES462758A1 (es) | 1978-12-16 |
| DK430577A (da) | 1978-03-31 |
| CH634070A5 (de) | 1983-01-14 |
| JPS6038421B2 (ja) | 1985-08-31 |
| BR7706506A (pt) | 1978-06-06 |
| DE2644265C2 (de) | 1983-02-10 |
| DE2644265A1 (de) | 1978-04-06 |
| JPS5681366A (en) | 1981-07-03 |
| BE859180A (fr) | 1978-03-29 |
| GB1554057A (en) | 1979-10-17 |
| FR2366337A1 (fr) | 1978-04-28 |
| US4225489A (en) | 1980-09-30 |
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