ES460952A1 - Procedimiento para la preparacion de derivados de cefem. - Google Patents
Procedimiento para la preparacion de derivados de cefem.Info
- Publication number
- ES460952A1 ES460952A1 ES460952A ES460952A ES460952A1 ES 460952 A1 ES460952 A1 ES 460952A1 ES 460952 A ES460952 A ES 460952A ES 460952 A ES460952 A ES 460952A ES 460952 A1 ES460952 A1 ES 460952A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- opt
- substd
- alkoxy
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001782 cephems Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- PVEOYINWKBTPIZ-UHFFFAOYSA-N but-3-enoic acid Chemical compound OC(=O)CC=C PVEOYINWKBTPIZ-UHFFFAOYSA-N 0.000 abstract 2
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 108010087702 Penicillinase Proteins 0.000 abstract 1
- 241000295644 Staphylococcaceae Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- -1 carbamoyloxy Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229950009506 penicillinase Drugs 0.000 abstract 1
- 125000005633 phthalidyl group Chemical group 0.000 abstract 1
- JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical compound C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la preparación de derivados de cefem de la fórmula general I **fórmula** en la que R 1, R 2 y R 3 significan hidrógeno o un radical acohilo con - en el caso de que n sea O-1 a 5 átomos de carbono o -en el caso de que n sea 1-1 a 3 átomos de carbono, R 4 significa hidrógeno , un radical alcohilo eventualmente sustituido, el radical ftalido, o un catión R 5 significa hidrógeno o un radical alcohilo con 1 a 3 átomos de carbono, a representa hidrógeno, alcoxi, halógeno o un grupo CH 2Y, significando Y hidrógeno, aciloxi, alcohiloxi, piridino eventualmente sustituido, carbamoiloxi eventualmente sustituido o una agrupación Sr 6, pudiendo representar R 6 un radical acilo , un radical alcohilo, o un heterociclo de 5 o 6 miembros, eventualmente sustituido , eventualmente condensado con un anillo aromático de 5 o 6 miembros
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762634082 DE2634082A1 (de) | 1976-07-29 | 1976-07-29 | Cephemderivate und verfahren zu ihrer herstellung |
| DE19762651395 DE2651395A1 (de) | 1976-11-11 | 1976-11-11 | Cephemderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES460952A1 true ES460952A1 (es) | 1978-12-01 |
Family
ID=25770753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES460952A Expired ES460952A1 (es) | 1976-07-29 | 1977-07-22 | Procedimiento para la preparacion de derivados de cefem. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5318598A (es) |
| ES (1) | ES460952A1 (es) |
| FR (1) | FR2359843A1 (es) |
| IT (1) | IT1085475B (es) |
| NL (1) | NL7708177A (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4379464A (en) * | 1981-02-18 | 1983-04-12 | Philip Morris Incorporated | Cooked flavors for smoking products |
| FR2550200B1 (fr) * | 1983-08-01 | 1988-04-08 | Fujisawa Pharmaceutical Co | Procede de preparation de composes de cephem a activite antimicrobienne et nouveaux produits ainsi obtenus |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3715043B2 (ja) * | 1996-09-25 | 2005-11-09 | 今村 弘 | ワーク取付用ハンガー |
| JPH1099867A (ja) * | 1996-09-27 | 1998-04-21 | Sony Corp | 廃水処理方法 |
-
1977
- 1977-07-22 NL NL7708177A patent/NL7708177A/xx not_active Application Discontinuation
- 1977-07-22 ES ES460952A patent/ES460952A1/es not_active Expired
- 1977-07-27 IT IT26217/77A patent/IT1085475B/it active
- 1977-07-29 JP JP9213477A patent/JPS5318598A/ja active Pending
- 1977-07-29 FR FR7723504A patent/FR2359843A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5318598A (en) | 1978-02-20 |
| NL7708177A (nl) | 1978-01-31 |
| IT1085475B (it) | 1985-05-28 |
| FR2359843A1 (fr) | 1978-02-24 |
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