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ES467739A1 - Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos - Google Patents

Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos

Info

Publication number
ES467739A1
ES467739A1 ES467739A ES467739A ES467739A1 ES 467739 A1 ES467739 A1 ES 467739A1 ES 467739 A ES467739 A ES 467739A ES 467739 A ES467739 A ES 467739A ES 467739 A1 ES467739 A1 ES 467739A1
Authority
ES
Spain
Prior art keywords
image
compounds
preparation
furanediyl
phenoxyphenylene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES467739A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19772711362 external-priority patent/DE2711362A1/de
Priority claimed from DE19782804835 external-priority patent/DE2804835A1/de
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES467739A1 publication Critical patent/ES467739A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la preparación de compuestos de bisbencimidazolil sustituidos de la fórmula general I **(Fórmula)** y sus sales fisiológicamente compatibles en la que A representa 2,5-tiofendiilo,2,5-furandiilo,p-fenileno, m- fenileno ó 4,4''¿fenoxifenileno. Los compuestos de la fórmula I encuentran utilización especialmente en medicamentos veterinarios. Los compuestos se caracterizan por un amplio espectro de acción, especialmente también contra cepas, resistentes a medicamentos, de los agentes patógenos mencionados anteriormente, por una dosis curativa mínima baja y una buena compatibilidad.
ES467739A 1977-03-16 1978-03-10 Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos Expired ES467739A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772711362 DE2711362A1 (de) 1977-03-16 1977-03-16 Substituierte bisbenzimidazolylthiophenverbindungen, ihre herstellung und verwendung
DE19782804835 DE2804835A1 (de) 1978-02-04 1978-02-04 Substituierte bisbenzimidazolylverbindungen, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
ES467739A1 true ES467739A1 (es) 1979-07-01

Family

ID=25771734

Family Applications (2)

Application Number Title Priority Date Filing Date
ES467739A Expired ES467739A1 (es) 1977-03-16 1978-03-10 Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos
ES475989A Expired ES475989A1 (es) 1977-03-16 1978-12-14 Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES475989A Expired ES475989A1 (es) 1977-03-16 1978-12-14 Procedimiento para la preparacion de compuestos de bisbenci-midazolil sustituidos.

Country Status (11)

Country Link
US (1) US4156778A (es)
JP (1) JPS53135978A (es)
AU (1) AU3415578A (es)
CA (1) CA1095038A (es)
ES (2) ES467739A1 (es)
FR (1) FR2383944A1 (es)
GB (1) GB1599102A (es)
IL (1) IL54275A0 (es)
IT (1) IT1094902B (es)
NL (1) NL7802848A (es)
NZ (1) NZ186689A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645874A (en) * 1982-07-16 1987-02-24 At&T Bell Laboratories Message routing through data communication networks
DE3305578A1 (de) * 1983-02-18 1984-08-23 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von 4,4'-bis-benz-ox(-thi,-imid) -azol-2-yl-stilbenen
US5643935A (en) * 1995-06-07 1997-07-01 The University Of North Carolina At Chapel Hill Method of combatting infectious diseases using dicationic bis-benzimidazoles
JP2001302643A (ja) * 2000-04-21 2001-10-31 Suntory Ltd 環状アミジン化合物
AU2002239508B9 (en) * 2000-12-07 2005-09-08 Gilead Palo Alto, Inc. Substituted 1, 3, 5-triazines and pyrimidines as ABCA-1 elevating compounds against coronary artery disease or atherosclerosis
CN101143854B (zh) * 2006-09-15 2011-01-05 沈阳化工研究院 一种双苯并噁唑类化合物的合成方法
WO2009043902A1 (en) * 2007-10-05 2009-04-09 Universite De Mons Hainaut Bisbenzimidazoles as antimalarial agents
CN102070551B (zh) * 2010-12-29 2012-06-20 河北星宇化工有限公司 2,2’-(4,4’-二苯乙烯基)双苯并噁唑的制备方法
CN109651370A (zh) * 2018-12-17 2019-04-19 桂林理工大学 一种嘌呤类衍生物自由基前体分子及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2733244A (en) * 1956-01-31 G-tetrahydropyrimidine and imidaz-
US3103518A (en) * 1958-01-14 1963-09-10 G -methoxybenzimidazole-
NL242891A (es) * 1958-09-02
US3337578A (en) * 1961-09-15 1967-08-22 Heidenheimer Chemisches Lab 2, 2'-alkylenebisbenzimidazoles
US3287469A (en) * 1963-09-27 1966-11-22 Du Pont Naphthyl-and indanylimidazolines
FR1451220A (fr) * 1963-10-11 1966-01-07 Merck & Co Inc Procédé de fabrication de benzimidazoles
FR1451219A (fr) * 1963-11-15 1966-01-07 Merck & Co Inc Procédé de fabrication de benzimidazoles 2-substitués
US3179669A (en) * 1964-06-15 1965-04-20 Upjohn Co Monohydroxy substituted 2, 2'-alkyli-denebisbenzimidazoles
JPS5024314B2 (es) * 1972-12-29 1975-08-14
GB1476464A (en) * 1974-11-20 1977-06-16 Wyeth John & Brother Ltd 9-tetrahydropyrimidinyl-and 9-imidazolinyl-fluorenols their preparation and their pharmaceutical compositions
US3992403A (en) * 1975-05-30 1976-11-16 Schering Corporation 2-Imidazolines and their use as hypoglycemic agents

Also Published As

Publication number Publication date
JPS53135978A (en) 1978-11-28
ES475989A1 (es) 1979-05-16
AU3415578A (en) 1979-09-20
GB1599102A (en) 1981-09-30
IT7821181A0 (it) 1978-03-13
FR2383944A1 (fr) 1978-10-13
NL7802848A (nl) 1978-09-19
NZ186689A (en) 1979-10-25
IL54275A0 (en) 1978-06-15
CA1095038A (en) 1981-02-03
IT1094902B (it) 1985-08-10
US4156778A (en) 1979-05-29

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