ES466493A1 - 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them - Google Patents
4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing themInfo
- Publication number
- ES466493A1 ES466493A1 ES466493A ES466493A ES466493A1 ES 466493 A1 ES466493 A1 ES 466493A1 ES 466493 A ES466493 A ES 466493A ES 466493 A ES466493 A ES 466493A ES 466493 A1 ES466493 A1 ES 466493A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- phenylbutyric acid
- pharmaceutical compostions
- compostions containing
- dervatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OBKXEAXTFZPCHS-UHFFFAOYSA-N 4-phenylbutyric acid Chemical compound OC(=O)CCCC1=CC=CC=C1 OBKXEAXTFZPCHS-UHFFFAOYSA-N 0.000 title 2
- 229950009215 phenylbutanoic acid Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The new compounds corresponding to the general formula: < IMAGE > in which X represents hydrogen, a halogen or an alkyl or alkoxy radical, and the compositions which contain them are useful as medicaments. The medicaments containing these active principles are useful in the treatment of painful inflammatory syndromes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7702959A FR2378741A1 (en) | 1977-02-01 | 1977-02-01 | GARYL GOXO ISOVALERIC ACIDS WITH ANTIPHLOGISTIC AND ANTALGIC PROPERTIES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES466493A1 true ES466493A1 (en) | 1979-05-01 |
Family
ID=9186227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES466493A Expired ES466493A1 (en) | 1977-02-01 | 1978-01-31 | 4-phenylbutyric acid dervatives process for their preparation and pharmaceutical compostions containing them |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE863196A (en) |
| CA (1) | CA1097684A (en) |
| CH (1) | CH628014A5 (en) |
| DE (1) | DE2804293A1 (en) |
| ES (1) | ES466493A1 (en) |
| FR (1) | FR2378741A1 (en) |
| GB (1) | GB1565616A (en) |
| NL (1) | NL7801057A (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS243570B1 (en) * | 1984-08-31 | 1986-06-12 | Miroslav Kuchar | Omega-aryloxoalkane acids |
| HRP950558A2 (en) * | 1994-11-15 | 1997-12-31 | Scott M. Wilhelm | Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors |
| US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
| US5886022A (en) * | 1995-06-05 | 1999-03-23 | Bayer Corporation | Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors |
| GB9522615D0 (en) * | 1995-11-03 | 1996-01-03 | Pharmacia Spa | 4-Phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity |
| HRP970247B1 (en) * | 1996-05-15 | 2002-02-28 | Bayer Ag | Substituted 4-arylbutric acid derivatives as matrix metalloprotease inhibitors |
| CO5080759A1 (en) | 1996-05-15 | 2001-09-25 | Bayer Corp | BIARILACETILENOS AS INHIBITORS OF THE METALOPROTEASE OF MATRIX |
| US5863915A (en) * | 1996-05-15 | 1999-01-26 | Bayer Corporation | Substituted 4-arylbutyric acid derivatives as matrix metalloprotease |
-
1977
- 1977-02-01 FR FR7702959A patent/FR2378741A1/en active Granted
-
1978
- 1978-01-23 BE BE184536A patent/BE863196A/en not_active IP Right Cessation
- 1978-01-30 CA CA295,903A patent/CA1097684A/en not_active Expired
- 1978-01-30 NL NL7801057A patent/NL7801057A/en not_active Application Discontinuation
- 1978-01-31 ES ES466493A patent/ES466493A1/en not_active Expired
- 1978-02-01 DE DE19782804293 patent/DE2804293A1/en active Granted
- 1978-02-01 GB GB404378A patent/GB1565616A/en not_active Expired
- 1978-02-01 CH CH110878A patent/CH628014A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1097684A (en) | 1981-03-17 |
| NL7801057A (en) | 1978-08-03 |
| DE2804293C2 (en) | 1989-08-03 |
| CH628014A5 (en) | 1982-02-15 |
| BE863196A (en) | 1978-05-16 |
| FR2378741A1 (en) | 1978-08-25 |
| GB1565616A (en) | 1980-04-23 |
| DE2804293A1 (en) | 1978-08-10 |
| FR2378741B1 (en) | 1980-02-22 |
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