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ES465906A1 - Un procedimiento de preparacion de comprimidos - Google Patents

Un procedimiento de preparacion de comprimidos

Info

Publication number
ES465906A1
ES465906A1 ES465906A ES465906A ES465906A1 ES 465906 A1 ES465906 A1 ES 465906A1 ES 465906 A ES465906 A ES 465906A ES 465906 A ES465906 A ES 465906A ES 465906 A1 ES465906 A1 ES 465906A1
Authority
ES
Spain
Prior art keywords
prolonged
making
methods
pharmaceutical compositions
oral administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465906A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique filed Critical LIPHA SAS
Publication of ES465906A1 publication Critical patent/ES465906A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un procedimiento de preparación de comprimidos, caracterizado porque se fabrican gránulo calibrados que contienen oxalato ácido de 3-(1-naftil)-2-tetrahidrofurfuril-propionato de 2-dietilamino-etilo, después se mezclan los gránulos con excipientes clásicos y se comprime la mezcla formada al objeto de obtener comprimidos aplicando una presión a la compresión tal que la rotura del comprimido se produzca por una presión comprendida entre 5 y 8 kg/cm2, y a continuación se recubren los comprimidos con una solución filmógena de hidroxipropilmetilcelulosa y etilcelulosa que contiene propilenglicol, cuyo contenido de etilcelulosa está comprendido entre 30 y 50%, preferiblemente entre 35 y 45%, y el de propilenglicol es de 8 a 15%, expresados en porcentaje en peso con respecto a la totalidad de los derivados celulósicos, de modo que el espesor del recubrimiento del comprimido corresponde a una toma de peso comprendida entre 1 y 2%.
ES465906A 1977-01-13 1978-12-01 Un procedimiento de preparacion de comprimidos Expired ES465906A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7700810A FR2377196A1 (fr) 1977-01-13 1977-01-13 Composition medicamenteuse a usage oral

Publications (1)

Publication Number Publication Date
ES465906A1 true ES465906A1 (es) 1979-01-01

Family

ID=9185421

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465906A Expired ES465906A1 (es) 1977-01-13 1978-12-01 Un procedimiento de preparacion de comprimidos

Country Status (6)

Country Link
US (1) US4155993A (es)
JP (1) JPS5394029A (es)
BE (1) BE862850A (es)
DE (1) DE2800654A1 (es)
ES (1) ES465906A1 (es)
FR (1) FR2377196A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
FR2453639A1 (fr) * 1979-04-09 1980-11-07 Sanofi Sa Composition medicamenteuse a liberation programmee immediate-retard a base de naftidrofuryl
FR2453641A1 (fr) * 1979-04-12 1980-11-07 Sanofi Sa Compositions therapeutiques a usage oral et a liberation programmee l'oxalate de naftidrofuryl
JPS5668609A (en) * 1979-11-07 1981-06-09 Nippon Kayaku Co Ltd Phthalazinol preparation
FR2506157A1 (fr) * 1981-05-20 1982-11-26 Lipha Preparation pharmaceutique de " naftidrofuryl " a liberation controlee
US4795327A (en) * 1984-03-26 1989-01-03 Forest Laboratories, Inc. Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants
US4695464A (en) * 1984-10-09 1987-09-22 The Dow Chemical Company Sustained release dosage form based on highly plasticized cellulose ether gels
US4678516A (en) * 1984-10-09 1987-07-07 The Dow Chemical Company Sustained release dosage form based on highly plasticized cellulose ether gels
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US4746476A (en) * 1986-10-10 1988-05-24 Hoechst Celanese Corporation Ultrathin polyphenylene oxide polymer films and their preparation
US4910082A (en) * 1986-10-10 1990-03-20 Hoechst Celanese Corp. Ultrathin polyphenylene oxide polymer films and their preparation
US4752470A (en) * 1986-11-24 1988-06-21 Mehta Atul M Controlled release indomethacin
JP2643222B2 (ja) * 1988-02-03 1997-08-20 エーザイ株式会社 多重層顆粒
US5175003A (en) * 1990-04-06 1992-12-29 Biosytes Usa, Inc. Dual mechanism controlled release system for drug dosage forms
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
DE19511131A1 (de) * 1995-03-27 1996-10-02 Basf Ag Mechanisch stabile feste Wirkstoffzubereitungsformen
US20060067999A1 (en) * 1996-03-25 2006-03-30 Wyeth Extended release formulation
GB9814411D0 (en) * 1998-07-03 1998-09-02 Mw Encap Limited Capsule sealing system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2887440A (en) * 1957-08-12 1959-05-19 Dow Chemical Co Enteric coating
NL265304A (es) 1960-05-31
FR1290661A (fr) * 1960-05-31 1962-04-13 Abbott Lab Méthode d'enrobage de comprimés
US3247066A (en) * 1962-09-12 1966-04-19 Parke Davis & Co Controlled release dosage form containing water-swellable beadlet
NL142872C (es) * 1963-03-28
US3388041A (en) * 1964-01-27 1968-06-11 Richardson Merrell Inc High dosage sustained release tablet
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
DE2010416B2 (de) * 1970-03-05 1979-03-29 Hoechst Ag, 6000 Frankfurt Oral anwendbare Arzneiform mit Retardwirkung
GB1468172A (en) * 1973-03-28 1977-03-23 Benzon As Alfred Oral drug preparations
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform

Also Published As

Publication number Publication date
FR2377196A1 (fr) 1978-08-11
US4155993A (en) 1979-05-22
DE2800654A1 (de) 1978-07-20
JPS5394029A (en) 1978-08-17
BE862850A (fr) 1978-07-12

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