ES454005A1 - Triazole derivatives and processes for the production thereof - Google Patents
Triazole derivatives and processes for the production thereofInfo
- Publication number
- ES454005A1 ES454005A1 ES454005A ES454005A ES454005A1 ES 454005 A1 ES454005 A1 ES 454005A1 ES 454005 A ES454005 A ES 454005A ES 454005 A ES454005 A ES 454005A ES 454005 A1 ES454005 A1 ES 454005A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- substituted
- formula
- optionally
- rings
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 title abstract 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- 150000007524 organic acids Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003852 triazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedure for obtaining triazole derivatives of general formula I, **(See formula)** where R1 signifies hydrogen, lower alkyl, hydroxymethyl, optionally esterified or ethereal, formyl, carboxy, optionally functionally modified or aminomethyl, optionally substituted, and rings A and B, independent of each other, may be unsubstituted or substituted, and its addition salts with inorganic and organic acids, characterized in that a compound of general formula II, **(See formula)** where R1 has the meaning indicated under formula I and rings A and B may be substituted as indicated therein, is reacted with formaldehyde and formic acid, and, if desired, a triazole derivative of general formula I, obtained is transformed in an addition salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH817574A CH601264A5 (en) | 1974-06-14 | 1974-06-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES454005A1 true ES454005A1 (en) | 1977-11-16 |
Family
ID=4336312
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES438481A Expired ES438481A1 (en) | 1974-06-14 | 1975-06-12 | Triazole derivatives and processes for the production thereof |
| ES454006A Expired ES454006A1 (en) | 1974-06-14 | 1976-12-06 | Triazole derivatives and processes for the production thereof |
| ES454008A Expired ES454008A1 (en) | 1974-06-14 | 1976-12-06 | Triazole derivatives and processes for the production thereof |
| ES454005A Expired ES454005A1 (en) | 1974-06-14 | 1976-12-06 | Triazole derivatives and processes for the production thereof |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES438481A Expired ES438481A1 (en) | 1974-06-14 | 1975-06-12 | Triazole derivatives and processes for the production thereof |
| ES454006A Expired ES454006A1 (en) | 1974-06-14 | 1976-12-06 | Triazole derivatives and processes for the production thereof |
| ES454008A Expired ES454008A1 (en) | 1974-06-14 | 1976-12-06 | Triazole derivatives and processes for the production thereof |
Country Status (22)
| Country | Link |
|---|---|
| JP (3) | JPS6028825B2 (en) |
| AT (2) | AT345821B (en) |
| AU (1) | AU496929B2 (en) |
| BE (1) | BE830214A (en) |
| CA (1) | CA1074313A (en) |
| CH (1) | CH601264A5 (en) |
| CS (1) | CS189712B2 (en) |
| DE (1) | DE2525691A1 (en) |
| DK (1) | DK227075A (en) |
| DO (1) | DOP1980002934A (en) |
| ES (4) | ES438481A1 (en) |
| FR (1) | FR2274302A1 (en) |
| GB (1) | GB1476116A (en) |
| GT (1) | GT198066871A (en) |
| HK (1) | HK49580A (en) |
| HU (1) | HU172467B (en) |
| IE (1) | IE41550B1 (en) |
| IL (1) | IL47474A (en) |
| MY (1) | MY8100158A (en) |
| NL (1) | NL7507104A (en) |
| SE (1) | SE426393B (en) |
| ZA (1) | ZA753809B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5855147B2 (en) * | 1976-06-04 | 1983-12-08 | 塩野義製薬株式会社 | benzophenone derivatives |
| CN113372215B (en) * | 2021-05-20 | 2024-05-24 | 吉林大学 | Novel esterification method for synthesizing p-halomethyl benzoate |
| JP2024537773A (en) | 2021-09-29 | 2024-10-16 | エフ． ホフマン－ラ ロシュ アーゲー | Novel benzodiazepine derivatives as GABA Aγ1 PAMs |
-
1974
- 1974-06-14 CH CH817574A patent/CH601264A5/xx not_active IP Right Cessation
-
1975
- 1975-05-23 DK DK227075A patent/DK227075A/en not_active Application Discontinuation
- 1975-05-26 SE SE7505952A patent/SE426393B/en not_active IP Right Cessation
- 1975-06-09 GB GB2461675A patent/GB1476116A/en not_active Expired
- 1975-06-10 DE DE19752525691 patent/DE2525691A1/en not_active Ceased
- 1975-06-11 FR FR7518236A patent/FR2274302A1/en active Granted
- 1975-06-12 AU AU82082/75A patent/AU496929B2/en not_active Expired
- 1975-06-12 CA CA229,230A patent/CA1074313A/en not_active Expired
- 1975-06-12 ES ES438481A patent/ES438481A1/en not_active Expired
- 1975-06-12 IL IL7547474A patent/IL47474A/en unknown
- 1975-06-13 BE BE157308A patent/BE830214A/en not_active IP Right Cessation
- 1975-06-13 IE IE1332/75A patent/IE41550B1/en unknown
- 1975-06-13 ZA ZA00753809A patent/ZA753809B/en unknown
- 1975-06-13 CS CS754192A patent/CS189712B2/en unknown
- 1975-06-13 NL NL7507104A patent/NL7507104A/en not_active Application Discontinuation
- 1975-06-13 HU HU75CI00001590A patent/HU172467B/en unknown
- 1975-06-13 AT AT455875A patent/AT345821B/en not_active IP Right Cessation
- 1975-06-14 JP JP7571466A patent/JPS6028825B2/en not_active Expired
-
1976
- 1976-12-06 ES ES454006A patent/ES454006A1/en not_active Expired
- 1976-12-06 ES ES454008A patent/ES454008A1/en not_active Expired
- 1976-12-06 ES ES454005A patent/ES454005A1/en not_active Expired
-
1977
- 1977-07-12 AT AT498877A patent/AT345822B/en not_active IP Right Cessation
-
1980
- 1980-09-04 HK HK495/80A patent/HK49580A/en unknown
- 1980-11-25 DO DO1980002934A patent/DOP1980002934A/en unknown
- 1980-12-12 GT GT198066871A patent/GT198066871A/en unknown
-
1981
- 1981-12-30 MY MY158/81A patent/MY8100158A/en unknown
-
1983
- 1983-11-25 JP JP58220863A patent/JPS6021984B2/en not_active Expired
- 1983-11-25 JP JP58220864A patent/JPS59108770A/en active Granted
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