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ES449162A1 - Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico. - Google Patents

Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.

Info

Publication number
ES449162A1
ES449162A1 ES449162A ES449162A ES449162A1 ES 449162 A1 ES449162 A1 ES 449162A1 ES 449162 A ES449162 A ES 449162A ES 449162 A ES449162 A ES 449162A ES 449162 A1 ES449162 A1 ES 449162A1
Authority
ES
Spain
Prior art keywords
alpha
tetranorprosta
trihydroxy
trans
antimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES449162A
Other languages
English (en)
Inventor
Joseph M Muchowsky
John H Fried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES449162A1 publication Critical patent/ES449162A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES449162A 1975-06-23 1975-06-23 Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico. Expired ES449162A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58921875A 1975-06-23 1975-06-23
US05/643,219 US3985791A (en) 1975-06-23 1975-12-22 16-Phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives

Publications (1)

Publication Number Publication Date
ES449162A1 true ES449162A1 (es) 1977-12-16

Family

ID=27080476

Family Applications (1)

Application Number Title Priority Date Filing Date
ES449162A Expired ES449162A1 (es) 1975-06-23 1975-06-23 Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.

Country Status (13)

Country Link
US (1) US3985791A (es)
AU (1) AU505899B2 (es)
CA (1) CA1064027A (es)
DE (1) DE2627910C2 (es)
ES (1) ES449162A1 (es)
FR (1) FR2315263B1 (es)
GB (1) GB1546823A (es)
HK (1) HK8780A (es)
IE (1) IE43916B1 (es)
MX (1) MX3949E (es)
MY (1) MY8000274A (es)
NL (1) NL181628C (es)
SE (2) SE417710B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178457A (en) * 1978-07-10 1979-12-11 Syntex (U.S.A.) Inc. (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
US4389414A (en) * 1981-05-11 1983-06-21 Syntex (U.S.A.) Inc. Prostaglandin compositions
US4912235A (en) * 1983-12-22 1990-03-27 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
US4804787A (en) * 1983-12-22 1989-02-14 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
DE3414509A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 9-halogen-prostaglandine
US4929740A (en) * 1984-10-09 1990-05-29 Syntex (U.S.A.) Inc. Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
NO163485C (no) * 1984-10-09 1990-06-06 Syntex Inc Mellomprodukter for fremstilling av 16-fenoksy- og 16-substituerte fenoksy-prostatriensyrederivater og fremgangsmaate ved fremstilling av mellomproduktene.
US4997823A (en) * 1986-02-18 1991-03-05 Syntex (U.S.A.) Inc. Anti-infective injectable formulations
ZA871143B (en) * 1986-02-18 1988-09-28 Syntex Inc Anti-infective injectable formulations
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US5248788A (en) * 1988-12-13 1993-09-28 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US4916238A (en) * 1988-12-13 1990-04-10 Syntex (U.S.A.) Inc. Process for preparing allenic prostanoic acid derivatives
US5571936A (en) * 1994-09-30 1996-11-05 Korea Institute Of Science And Technology Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
AU2003272962A1 (en) * 2002-10-10 2004-05-04 Shuh Narumiya Remedies for allergic diseases
US20070270489A1 (en) 2003-07-25 2007-11-22 Ono Pharmaceutical Co., Ltd. Remedy for Cartilage-Related Diseases
EP2143712A1 (en) * 2008-07-10 2010-01-13 Sandoz AG Improved Process for the Production of Prostaglandins and Prostaglandin Analogs
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
EP2349242B1 (en) * 2008-10-29 2018-12-05 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
CN101948484B (zh) * 2010-09-19 2012-07-11 武汉武药科技有限公司 一种曲伏前列素中间体的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879438A (en) * 1973-03-05 1975-04-22 Syntex Inc 4,5,13-Prostatrienoic acid derivatives
DD118856A5 (es) * 1972-11-08 1976-03-20
US3864387A (en) 1973-05-21 1975-02-04 Upjohn Co 5-Oxa phenyl-and phenoxy-substituted prostaglandin F{HD 1{301 {0 {B analogs
US3873598A (en) * 1973-07-06 1975-03-25 Syntex Inc 4,5,10,13 prostatetraenoic acid derivatives
GB1445794A (en) * 1974-02-18 1976-08-11 Ici Ltd Epimerisation process for lactone intermediates for prostaglandins

Also Published As

Publication number Publication date
AU505899B2 (en) 1979-12-06
GB1546823A (en) 1979-05-31
IE43916B1 (en) 1981-07-01
HK8780A (en) 1980-03-14
SE8008334L (sv) 1980-11-27
SE417710B (sv) 1981-04-06
US3985791A (en) 1976-10-12
CA1064027A (en) 1979-10-09
DE2627910C2 (de) 1985-01-17
NL181628C (nl) 1987-10-01
NL7606723A (nl) 1976-12-27
MY8000274A (en) 1980-12-31
SE424636B (sv) 1982-08-02
IE43916L (en) 1976-12-23
MX3949E (es) 1981-10-09
DE2627910A1 (de) 1977-01-13
AU1507976A (en) 1978-01-05
FR2315263A1 (fr) 1977-01-21
FR2315263B1 (fr) 1978-11-10
SE7607075L (sv) 1976-12-24

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