ES449142A1 - Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins - Google Patents
Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporinsInfo
- Publication number
- ES449142A1 ES449142A1 ES449142A ES449142A ES449142A1 ES 449142 A1 ES449142 A1 ES 449142A1 ES 449142 A ES449142 A ES 449142A ES 449142 A ES449142 A ES 449142A ES 449142 A1 ES449142 A1 ES 449142A1
- Authority
- ES
- Spain
- Prior art keywords
- oxoimidazolidinyl
- carbonylamino
- alpha
- preparation
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins Chemical class 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 239000003782 beta lactam antibiotic agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002132 β-lactam antibiotic Substances 0.000 abstract 1
- 229940124586 β-lactam antibiotics Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
beta -Lactam antibiotics of the formula < IMAGE > in which the substituents are defined in Claim 1, are prepared. These compounds are obtained by reacting corresponding cephem compounds which have the ester grouping CH2OCOCH3 in position 3 with a compound providing the radical T. The resulting compounds can be used as antibacterial agents.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752528077 DE2528077A1 (en) | 1975-06-24 | 1975-06-24 | BETA-LACTAMANTIBIOTICS, THE METHOD OF MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449142A1 true ES449142A1 (en) | 1977-07-16 |
Family
ID=5949818
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449142A Expired ES449142A1 (en) | 1975-06-24 | 1976-06-23 | Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS523094A (en) |
| AT (1) | AT348118B (en) |
| AU (1) | AU498095B2 (en) |
| BE (1) | BE843343A (en) |
| CH (1) | CH628056A5 (en) |
| DD (1) | DD132344A5 (en) |
| DE (1) | DE2528077A1 (en) |
| DK (1) | DK281176A (en) |
| ES (1) | ES449142A1 (en) |
| FI (1) | FI761806A7 (en) |
| FR (1) | FR2317302A1 (en) |
| GB (1) | GB1539053A (en) |
| GR (1) | GR60559B (en) |
| IL (1) | IL49848A0 (en) |
| LU (1) | LU75216A1 (en) |
| NL (1) | NL7606788A (en) |
| SE (1) | SE7607217L (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5331690A (en) * | 1976-09-01 | 1978-03-25 | Shionogi & Co Ltd | Oxadithiacephalosporins |
| JPS61246187A (en) * | 1985-09-05 | 1986-11-01 | Shionogi & Co Ltd | 1-oxadethiacepham compound |
| JPH02117677A (en) * | 1989-09-22 | 1990-05-02 | Shionogi & Co Ltd | 1-oxadithiacepham compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2233067A1 (en) * | 1973-06-12 | 1975-01-10 | Beecham Group Ltd | N-(thio)acyl carbamoyl-glycylamino-cephalosporin ic acids - as antibiotics esp. active against pseudomonas and gram neg. organisms producing cephalosporinase |
| DE2407715C2 (en) * | 1974-02-18 | 1982-12-02 | Bayer Ag, 5090 Leverkusen | Cephalosporins, processes for their production, as well as pharmaceuticals |
-
1975
- 1975-06-24 DE DE19752528077 patent/DE2528077A1/en not_active Withdrawn
-
1976
- 1976-06-21 CH CH790476A patent/CH628056A5/en not_active IP Right Cessation
- 1976-06-21 IL IL49848A patent/IL49848A0/en unknown
- 1976-06-22 DD DD7600193506A patent/DD132344A5/en unknown
- 1976-06-22 GR GR51063A patent/GR60559B/en unknown
- 1976-06-22 JP JP51072862A patent/JPS523094A/en active Pending
- 1976-06-22 LU LU75216A patent/LU75216A1/xx unknown
- 1976-06-22 FI FI761806A patent/FI761806A7/fi unknown
- 1976-06-22 NL NL7606788A patent/NL7606788A/en not_active Application Discontinuation
- 1976-06-22 GB GB25845/76A patent/GB1539053A/en not_active Expired
- 1976-06-23 DK DK281176A patent/DK281176A/en unknown
- 1976-06-23 SE SE7607217A patent/SE7607217L/en unknown
- 1976-06-23 ES ES449142A patent/ES449142A1/en not_active Expired
- 1976-06-24 FR FR7619245A patent/FR2317302A1/en active Granted
- 1976-06-24 AU AU15222/76A patent/AU498095B2/en not_active Expired
- 1976-06-24 BE BE168254A patent/BE843343A/en unknown
- 1976-06-24 AT AT461376A patent/AT348118B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| LU75216A1 (en) | 1977-03-15 |
| AT348118B (en) | 1979-01-25 |
| NL7606788A (en) | 1976-12-28 |
| GR60559B (en) | 1978-06-22 |
| FR2317302A1 (en) | 1977-02-04 |
| CH628056A5 (en) | 1982-02-15 |
| DD132344A5 (en) | 1978-09-20 |
| ATA461376A (en) | 1978-06-15 |
| FR2317302B1 (en) | 1980-07-11 |
| AU498095B2 (en) | 1979-02-08 |
| DE2528077A1 (en) | 1977-01-20 |
| BE843343A (en) | 1976-12-24 |
| JPS523094A (en) | 1977-01-11 |
| AU1522276A (en) | 1978-01-05 |
| SE7607217L (en) | 1976-12-25 |
| FI761806A7 (en) | 1976-12-25 |
| IL49848A0 (en) | 1976-08-31 |
| DK281176A (en) | 1976-12-25 |
| GB1539053A (en) | 1979-01-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EG10530A (en) | Process for preparation of 7-aminocephalosporanic acid derivatives having a substituent at position 7,their use as antibiotics | |
| IE36725B1 (en) | Tetrazole derivatives | |
| ES426003A1 (en) | {60 -amino-{60 -(ureidophenyl)acetamidocephalosporins | |
| ES412859A1 (en) | Process for preparing 7-(alpha-hydroxy-alpha-phenyl)acetamido-3-(1-methyl-1h-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and derivatives thereof | |
| AU499337B2 (en) | Penicillins & cephalosporins | |
| CA1027555A (en) | Cephalosporin compounds | |
| IE40169B1 (en) | 7- (-(halomethyl-aryl)-acetamido)cephalosporin derivatives | |
| ES449142A1 (en) | Process for the preparation of alpha-(2-oxoimidazolidinyl carbonylamino)-acetamido cephalosporins | |
| IL113744A0 (en) | 3-Cephem derivatives and their preparation | |
| ES405994A1 (en) | Cephalosporins | |
| FR2361114A1 (en) | PROCESS FOR THE PREPARATION OF ANALOGUES OF CEPHALOSPORIN WITH ANTIBACTERIAL PROPERTY AND NEW PRODUCTS THUS OBTAINED | |
| ES405555A1 (en) | 7-Alkoxycarbonyl-4-hydroxymethyl-1-phthalazone compounds | |
| CA1032533A (en) | Process for the production of cephalosporin compounds | |
| AU465060B2 (en) | Process for preparing primary 3 carbamoyloxymethyl cephalosporins | |
| IE38615L (en) | Penicillin compounds | |
| SE7612961L (en) | TIENAMYCIN DERIVATIVES | |
| ES431690A1 (en) | 7-{8 (2-Oxo-1-pyridinyl)acylamino{9 cephalosporin derivatives | |
| IE42191L (en) | 7ó-methoxy cephalosporin compounds. | |
| IE39233L (en) | Pyridino-dibenzo-azepine,-diazepine, -oxazepine and¹-thiazepine derivatives | |
| ES423024A1 (en) | Novel acid compounds | |
| FR2361403A1 (en) | 7-12- (2-IMINO-3-HYDROXY-4-THIAZOLIN-4-ML) -ACETAMIDO) ANTIBIOTICS | |
| GB1557423A (en) | Cephalosporins | |
| ES435003A1 (en) | Process for N-acylation of 7 amino cephem compounds | |
| CA1031324A (en) | 3-(morpholinoalkoxyiminomethyl)cephem compounds | |
| ES425469A1 (en) | Penicillins |