ES431190A1 - A procedure for the production of a penicillin derivative. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the production of a penicillin derivative. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES431190A1 ES431190A1 ES431190A ES431190A ES431190A1 ES 431190 A1 ES431190 A1 ES 431190A1 ES 431190 A ES431190 A ES 431190A ES 431190 A ES431190 A ES 431190A ES 431190 A1 ES431190 A1 ES 431190A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- translation
- production
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000002960 penicillins Chemical class 0.000 title abstract 2
- -1 p-hydroxyphenyl group Chemical group 0.000 abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the production of a penicillin derivative represented by the formula: **(See formula)** where ring A represents a single or fused, 5- or 6-membered ring, which may contain one or more nitrogen atoms, oxygen atoms or sulfur atoms; R1, R2 and R3, which may be the same or different, each represent a hydrogen atom, a hydroxy group, a lower alkyl group, a nitro group, a halogen atom or an oxo group; and B represents a p-hydroxyphenyl group or a 1,4-cyclohexadien-1-yl group, and its non-toxic and pharmaceutically acceptable salts, the method of which is to react a penicillin represented by the formula: **(See formula)** where B has the meaning given above, with a carboxylic acid represented by the formula: **(See formula)** where ring A, R1, R2 and R3 have the meaning given above or with a reactive derivative thereof. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP48118390A JPS5064294A (en) | 1973-10-19 | 1973-10-19 | |
| JP12906773A JPS5077391A (en) | 1973-11-16 | 1973-11-16 | |
| JP3814674A JPS50130780A (en) | 1974-04-04 | 1974-04-04 | |
| JP8635574A JPS5116690A (en) | 1974-07-27 | 1974-07-27 | Penishirinjudotaino shinseiho |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES431190A1 true ES431190A1 (en) | 1977-04-01 |
Family
ID=27460538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES431190A Expired ES431190A1 (en) | 1973-10-19 | 1974-10-19 | A procedure for the production of a penicillin derivative. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES431190A1 (en) |
-
1974
- 1974-10-19 ES ES431190A patent/ES431190A1/en not_active Expired
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