ES420536A1 - Benzotriazine compounds their production and their pharmaceu tical use - Google Patents
Benzotriazine compounds their production and their pharmaceu tical useInfo
- Publication number
- ES420536A1 ES420536A1 ES420536A ES420536A ES420536A1 ES 420536 A1 ES420536 A1 ES 420536A1 ES 420536 A ES420536 A ES 420536A ES 420536 A ES420536 A ES 420536A ES 420536 A1 ES420536 A1 ES 420536A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- production
- compounds
- pharmaceu tical
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- OWQPOVKKUWUEKE-UHFFFAOYSA-N 1,2,3-benzotriazine Chemical class N1=NN=CC2=CC=CC=C21 OWQPOVKKUWUEKE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- BHHRGAKNBXQGIO-UHFFFAOYSA-N 1,2,4-benzotriazin-3-amine Chemical class C1=CC=CC2=NC(N)=NN=C21 BHHRGAKNBXQGIO-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/08—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 condensed with carbocyclic rings or ring systems
- C07D253/10—Condensed 1,2,4-triazines; Hydrogenated condensed 1,2,4-triazines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Fodder In General (AREA)
- Cosmetics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedure for the production of new derivatives of 3-amino-benzo-1,2,4-triazine di-N-oxide (1,4), of formula I: ** (See formula) ** in which R represents alkyl with 1 to 4 carbon atoms, characterized in that compounds of formula II: ** (See formula) ** they are reacted at temperatures between about 0º and 150ºC with a member of the group comprising alkylation compounds of formula III: R - Y (III) in which R has the meaning indicated above and Y represents the active group of an alkylating agent, which is cleaved in the reaction. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2255947A DE2255947A1 (en) | 1972-11-15 | 1972-11-15 | SUBSTITUTED 3-AMINO-BENZO-1,2,4TRIAZINE-DI-N-OXIDES (1,4), METHOD FOR MANUFACTURING AND USING THEM AS ANTIMICROBIAL AGENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES420536A1 true ES420536A1 (en) | 1976-07-01 |
Family
ID=5861794
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES420536A Expired ES420536A1 (en) | 1972-11-15 | 1973-11-14 | Benzotriazine compounds their production and their pharmaceu tical use |
| ES444360A Expired ES444360A1 (en) | 1972-11-15 | 1976-01-16 | Benzotriazine compounds their production and their pharmaceu tical use |
| ES444359A Expired ES444359A1 (en) | 1972-11-15 | 1976-01-16 | Benzotriazine compounds their production and their pharmaceu tical use |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES444360A Expired ES444360A1 (en) | 1972-11-15 | 1976-01-16 | Benzotriazine compounds their production and their pharmaceu tical use |
| ES444359A Expired ES444359A1 (en) | 1972-11-15 | 1976-01-16 | Benzotriazine compounds their production and their pharmaceu tical use |
Country Status (19)
| Country | Link |
|---|---|
| JP (2) | JPS4980085A (en) |
| AR (3) | AR200888A1 (en) |
| AT (1) | AT331806B (en) |
| BE (1) | BE807309A (en) |
| BR (1) | BR7308877D0 (en) |
| CH (2) | CH592069A5 (en) |
| CS (1) | CS178138B2 (en) |
| DE (1) | DE2255947A1 (en) |
| DK (1) | DK593374A (en) |
| ES (3) | ES420536A1 (en) |
| FR (1) | FR2206104B1 (en) |
| GB (1) | GB1423585A (en) |
| HU (1) | HU168359B (en) |
| IL (1) | IL43614A (en) |
| LU (1) | LU68790A1 (en) |
| NL (1) | NL7315454A (en) |
| PL (2) | PL87635B1 (en) |
| SU (1) | SU519134A3 (en) |
| ZA (1) | ZA738726B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7801827A (en) * | 1977-02-22 | 1978-08-24 | Ciba Geigy | NEW HETEROCYCLIC COMPOUNDS. |
| NZ194612A (en) * | 1979-08-31 | 1982-12-21 | Ici Australia Ltd | Benzotriazine derivatives intermediates and herbicidal compositions |
| US5672702A (en) * | 1995-12-04 | 1997-09-30 | Sanofi | Process for preparing 3 amino 1, 2, 4-benzotriazine dioxide |
| AU2005231507B2 (en) | 2004-04-08 | 2012-03-01 | Targegen, Inc. | Benzotriazine inhibitors of kinases |
| EP1799656A4 (en) | 2004-08-25 | 2009-09-02 | Targegen Inc | Heterocyclic compounds and methods of use |
| CN115894385B (en) * | 2023-01-09 | 2025-02-07 | 中国科学院长春应用化学研究所 | Tirapazamine derivatives and preparation methods and applications thereof |
-
1972
- 1972-11-15 DE DE2255947A patent/DE2255947A1/en active Pending
-
1973
- 1973-11-12 IL IL7343614A patent/IL43614A/en unknown
- 1973-11-12 NL NL7315454A patent/NL7315454A/xx not_active Application Discontinuation
- 1973-11-13 BR BR8877/73A patent/BR7308877D0/en unknown
- 1973-11-13 CH CH1594273A patent/CH592069A5/xx not_active IP Right Cessation
- 1973-11-13 PL PL1973166510A patent/PL87635B1/pl unknown
- 1973-11-13 JP JP48126878A patent/JPS4980085A/ja active Pending
- 1973-11-13 PL PL1973183473A patent/PL99366B1/en unknown
- 1973-11-13 SU SU1967994A patent/SU519134A3/en active
- 1973-11-13 CH CH200477A patent/CH592070A5/xx not_active IP Right Cessation
- 1973-11-13 JP JP48126879A patent/JPS4980218A/ja active Pending
- 1973-11-13 LU LU68790A patent/LU68790A1/xx unknown
- 1973-11-14 ES ES420536A patent/ES420536A1/en not_active Expired
- 1973-11-14 BE BE137737A patent/BE807309A/en unknown
- 1973-11-14 CS CS7821A patent/CS178138B2/cs unknown
- 1973-11-14 HU HUBA2995A patent/HU168359B/hu unknown
- 1973-11-14 ZA ZA738726A patent/ZA738726B/en unknown
- 1973-11-15 AT AT961273A patent/AT331806B/en not_active IP Right Cessation
- 1973-11-15 AR AR251017A patent/AR200888A1/en active
- 1973-11-15 FR FR7340749A patent/FR2206104B1/fr not_active Expired
- 1973-11-15 GB GB5307073A patent/GB1423585A/en not_active Expired
-
1974
- 1974-11-14 DK DK593374A patent/DK593374A/da unknown
- 1974-11-15 AR AR256554A patent/AR200983A1/en active
- 1974-11-15 AR AR256553A patent/AR203770A1/en active
-
1976
- 1976-01-16 ES ES444360A patent/ES444360A1/en not_active Expired
- 1976-01-16 ES ES444359A patent/ES444359A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AR200888A1 (en) | 1974-12-27 |
| BR7308877D0 (en) | 1974-09-24 |
| BE807309A (en) | 1974-05-14 |
| CS178138B2 (en) | 1977-08-31 |
| HU168359B (en) | 1976-04-28 |
| AU6242873A (en) | 1975-05-15 |
| CH592070A5 (en) | 1977-10-14 |
| DK593374A (en) | 1975-05-20 |
| ATA961273A (en) | 1975-12-15 |
| ZA738726B (en) | 1974-09-25 |
| LU68790A1 (en) | 1974-01-21 |
| JPS4980085A (en) | 1974-08-02 |
| AR200983A1 (en) | 1974-12-27 |
| ES444359A1 (en) | 1977-05-16 |
| NL7315454A (en) | 1974-05-17 |
| AR203770A1 (en) | 1975-10-15 |
| GB1423585A (en) | 1976-02-04 |
| FR2206104A1 (en) | 1974-06-07 |
| DE2255947A1 (en) | 1974-05-22 |
| CH592069A5 (en) | 1977-10-14 |
| PL87635B1 (en) | 1976-07-31 |
| SU519134A3 (en) | 1976-06-25 |
| ES444360A1 (en) | 1977-05-16 |
| JPS4980218A (en) | 1974-08-02 |
| FR2206104B1 (en) | 1977-09-02 |
| IL43614A0 (en) | 1974-03-14 |
| PL99366B1 (en) | 1978-07-31 |
| IL43614A (en) | 1977-06-30 |
| AT331806B (en) | 1976-08-25 |
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