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ES420004A1 - Nitrosourea derivatives - Google Patents

Nitrosourea derivatives

Info

Publication number
ES420004A1
ES420004A1 ES420004A ES420004A ES420004A1 ES 420004 A1 ES420004 A1 ES 420004A1 ES 420004 A ES420004 A ES 420004A ES 420004 A ES420004 A ES 420004A ES 420004 A1 ES420004 A1 ES 420004A1
Authority
ES
Spain
Prior art keywords
formula
represent
group
hydrogen atom
derivative represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES420004A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10829672A external-priority patent/JPS4966688A/ja
Priority claimed from JP11001672A external-priority patent/JPS4969676A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES420004A1 publication Critical patent/ES420004A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A procedure for the preparation of a nitrosourea derivative represented by the formula: **(See formula)** where R1 and R2, which may be the same or different, each represent a hydrogen atom, a lower alkyl group, a cycloalkyl group, a lower alkanoyl group or a lower alkoxy group and n is an integer from 1 to 5, where n 1 when R1 and R2 each represent a hydrogen atom; whose procedure consists of nitrosating the urea derivative represented by the formula: **(See formula)** where R1, R2 and n have the meaning given above. (Machine-translation by Google Translate, not legally binding)
ES420004A 1972-10-28 1973-10-26 Nitrosourea derivatives Expired ES420004A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10829672A JPS4966688A (en) 1972-10-28 1972-10-28
JP11001672A JPS4969676A (en) 1972-11-02 1972-11-02

Publications (1)

Publication Number Publication Date
ES420004A1 true ES420004A1 (en) 1976-10-01

Family

ID=26448222

Family Applications (1)

Application Number Title Priority Date Filing Date
ES420004A Expired ES420004A1 (en) 1972-10-28 1973-10-26 Nitrosourea derivatives

Country Status (8)

Country Link
AT (1) AT335462B (en)
CA (1) CA1018979A (en)
CH (1) CH599161A5 (en)
DE (1) DE2351724A1 (en)
ES (1) ES420004A1 (en)
FR (1) FR2204414B1 (en)
GB (1) GB1408353A (en)
NL (1) NL7314785A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2116248A1 (en) * 2001-09-05 2009-11-11 Minerva Biotechnologies Corporation Compositions and Methods of Treatment of Cancer

Also Published As

Publication number Publication date
CA1018979A (en) 1977-10-11
CH599161A5 (en) 1978-05-12
AU6193573A (en) 1975-05-01
AT335462B (en) 1977-03-10
FR2204414A1 (en) 1974-05-24
NL7314785A (en) 1974-05-01
FR2204414B1 (en) 1978-07-28
GB1408353A (en) 1975-10-01
DE2351724A1 (en) 1974-05-09
ATA877173A (en) 1976-07-15

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