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ES429708A1 - 7,8-dihydroisomorphines - Google Patents

7,8-dihydroisomorphines

Info

Publication number
ES429708A1
ES429708A1 ES429708A ES429708A ES429708A1 ES 429708 A1 ES429708 A1 ES 429708A1 ES 429708 A ES429708 A ES 429708A ES 429708 A ES429708 A ES 429708A ES 429708 A1 ES429708 A1 ES 429708A1
Authority
ES
Spain
Prior art keywords
acid
dihydroisomorphine
salts
hydroxy
dihydromorphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES429708A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alkaloida Chemical Co Zrt
Original Assignee
Alkaloida Chemical Co Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Chemical Co Zrt filed Critical Alkaloida Chemical Co Zrt
Publication of ES429708A1 publication Critical patent/ES429708A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of new derivatives of 7,8-dihydroisomorphine and, more particularly, of 6-deoxy-6-acid-7,3-dihydroisomorphine and 6-deoxy-6-acid-14-hydroxy-7,8-dihydroisomorphine or its derivatives or its 3-protected salts, characterized in that the hydroxy groups fixed in positions 3 and 6 of 7,8-dihydromorphine and 14-hydroxy-7,8-dihydromorphine are blocked, the compounds obtained are reacted with a metallic acid or a substance that provides acid groups under the reaction conditions and, if desired, the blocking group 0 fixed in position 3 of the obtained substances is split and/or, if desired, the products are converted into their salts or their free bases are released from the salts. (Machine-translation by Google Translate, not legally binding)
ES429708A 1973-09-04 1974-08-31 7,8-dihydroisomorphines Expired ES429708A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUAA750A HU169430B (en) 1973-09-04 1973-09-04

Publications (1)

Publication Number Publication Date
ES429708A1 true ES429708A1 (en) 1977-06-16

Family

ID=10992987

Family Applications (1)

Application Number Title Priority Date Filing Date
ES429708A Expired ES429708A1 (en) 1973-09-04 1974-08-31 7,8-dihydroisomorphines

Country Status (15)

Country Link
JP (1) JPS5050400A (en)
AR (1) AR219471A1 (en)
BE (1) BE819545A (en)
CA (1) CA1021776A (en)
CH (1) CH605957A5 (en)
DE (2) DE2462592C2 (en)
DK (1) DK143851C (en)
ES (1) ES429708A1 (en)
FI (1) FI56838C (en)
FR (1) FR2242102B1 (en)
GB (1) GB1484988A (en)
HU (1) HU169430B (en)
NL (1) NL7411614A (en)
SE (1) SE418501B (en)
SU (1) SU615859A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5549600Y2 (en) * 1975-12-25 1980-11-18
AU686203B2 (en) * 1993-07-23 1998-02-05 Toray Industries, Inc. Morphinan derivative and medicinal use

Also Published As

Publication number Publication date
FI258274A7 (en) 1975-03-05
FR2242102B1 (en) 1977-11-04
SU615859A3 (en) 1978-07-15
FR2242102A1 (en) 1975-03-28
GB1484988A (en) 1977-09-08
DE2462592C2 (en) 1984-03-01
DK465974A (en) 1975-05-05
SE418501B (en) 1981-06-09
DE2441533A1 (en) 1975-03-20
DK143851C (en) 1982-04-05
SE7411053L (en) 1975-03-05
NL7411614A (en) 1975-03-06
BE819545A (en) 1974-12-31
FI56838B (en) 1979-12-31
FI56838C (en) 1980-04-10
HU169430B (en) 1976-11-28
CA1021776A (en) 1977-11-29
AR219471A1 (en) 1980-08-29
CH605957A5 (en) 1978-10-13
DE2441533C2 (en) 1984-02-09
DK143851B (en) 1981-10-19
JPS5050400A (en) 1975-05-06

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