ES424272A1 - Un procedimiento para preparar n - (2 - amino - 3,5 - di- bromobencil) - n - metilciclohexilamina terapeuticamente va-liosa. - Google Patents
Un procedimiento para preparar n - (2 - amino - 3,5 - di- bromobencil) - n - metilciclohexilamina terapeuticamente va-liosa.Info
- Publication number
- ES424272A1 ES424272A1 ES424272A ES424272A ES424272A1 ES 424272 A1 ES424272 A1 ES 424272A1 ES 424272 A ES424272 A ES 424272A ES 424272 A ES424272 A ES 424272A ES 424272 A1 ES424272 A1 ES 424272A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- amino
- see formula
- dibromobenzyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OJGDCBLYJGHCIH-UHFFFAOYSA-N bromhexine Chemical compound C1CCCCC1N(C)CC1=CC(Br)=CC(Br)=C1N OJGDCBLYJGHCIH-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 2-amino-3,5-dibromobenzyl Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- XTUVJUMINZSXGF-UHFFFAOYSA-N N-methylcyclohexylamine Chemical compound CNC1CCCCC1 XTUVJUMINZSXGF-UHFFFAOYSA-N 0.000 abstract 1
- PAMIQIKDUOTOBW-UHFFFAOYSA-N N-methylcyclohexylamine Natural products CN1CCCCC1 PAMIQIKDUOTOBW-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI78673 | 1973-03-15 | ||
| FI2122/73A FI55647C (fi) | 1973-07-02 | 1973-07-02 | Foerfarande foer framstaellning av terapeutiskt vaerdefull 2-amino-n-cyklohexyl-3,5-dibrom-n-metylbensylamin och dess syraadditionssalter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES424272A1 true ES424272A1 (es) | 1976-05-16 |
Family
ID=26156383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES424272A Expired ES424272A1 (es) | 1973-03-15 | 1974-03-14 | Un procedimiento para preparar n - (2 - amino - 3,5 - di- bromobencil) - n - metilciclohexilamina terapeuticamente va-liosa. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5328906B2 (bg) |
| AT (1) | AT333249B (bg) |
| BG (1) | BG23745A3 (bg) |
| CH (1) | CH613938A5 (bg) |
| DE (1) | DE2411848A1 (bg) |
| ES (1) | ES424272A1 (bg) |
| HU (1) | HU166949B (bg) |
| NL (1) | NL7403155A (bg) |
| NO (1) | NO139558C (bg) |
| RO (1) | RO69817A (bg) |
| SE (2) | SE396216B (bg) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8771807B2 (en) * | 2011-05-24 | 2014-07-08 | Air Products And Chemicals, Inc. | Organoaminosilane precursors and methods for making and using same |
| CN102924295B (zh) * | 2012-10-09 | 2014-10-29 | 石家庄东方药业有限公司 | 一种盐酸溴己新晶体及其制备方法和用途 |
| CN103145564B (zh) * | 2013-03-15 | 2014-06-18 | 湖北美林药业有限公司 | 盐酸溴己新化合物及其药物组合物 |
| CN109535010B (zh) * | 2018-12-27 | 2021-10-26 | 广州一品红制药有限公司 | 一种盐酸溴己新的制备方法 |
-
1973
- 1973-07-18 SE SE7310071A patent/SE396216B/xx unknown
- 1973-07-31 NO NO306373A patent/NO139558C/no unknown
-
1974
- 1974-03-08 NL NL7403155A patent/NL7403155A/xx not_active Application Discontinuation
- 1974-03-12 DE DE2411848A patent/DE2411848A1/de active Pending
- 1974-03-13 BG BG026039A patent/BG23745A3/bg unknown
- 1974-03-13 HU HUTO000957 patent/HU166949B/hu unknown
- 1974-03-13 RO RO7800574A patent/RO69817A/ro unknown
- 1974-03-14 AT AT212974A patent/AT333249B/de not_active IP Right Cessation
- 1974-03-14 ES ES424272A patent/ES424272A1/es not_active Expired
- 1974-03-15 JP JP2986274A patent/JPS5328906B2/ja not_active Expired
- 1974-03-15 CH CH366874A patent/CH613938A5/xx not_active IP Right Cessation
-
1975
- 1975-12-09 SE SE7513882A patent/SE7513882L/ not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AT333249B (de) | 1976-11-10 |
| NO139558C (no) | 1979-04-04 |
| RO69817A (fr) | 1980-12-30 |
| NL7403155A (bg) | 1974-09-17 |
| ATA212974A (de) | 1976-03-15 |
| SE7513882L (sv) | 1975-12-09 |
| CH613938A5 (en) | 1979-10-31 |
| JPS5328906B2 (bg) | 1978-08-17 |
| NO139558B (no) | 1978-12-27 |
| DE2411848A1 (de) | 1974-09-26 |
| JPS5046643A (bg) | 1975-04-25 |
| SE396216B (sv) | 1977-09-12 |
| HU166949B (bg) | 1975-06-28 |
| BG23745A3 (bg) | 1977-10-12 |
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