ES413935A1 - A procedure for preparation of istitezolic derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparation of istitezolic derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES413935A1 ES413935A1 ES413935A ES413935A ES413935A1 ES 413935 A1 ES413935 A1 ES 413935A1 ES 413935 A ES413935 A ES 413935A ES 413935 A ES413935 A ES 413935A ES 413935 A1 ES413935 A1 ES 413935A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- radical
- translation
- derivatives
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- CKDWPUIZGOQOOM-UHFFFAOYSA-N Carbamyl chloride Chemical compound NC(Cl)=O CKDWPUIZGOQOOM-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
A procedure for preparing isothiazolic derivatives of general formula I: **(See formula)** where R1 represents hydrogen or an alcoholic radical, and R2 represents an alcoholic radical, or an alkenyl radical optionally substituted with a halogen or an alkoxy, or an acyl radical, or a carbalkoxy radical, comprising the alcoholic, alkenyl and acyl radicals defined above from 1 to 6 carbon atoms, characterized in that the 3-hydroxy-5-methyl-l, 2-thiazole of formula II is reacted: **(See formula)** with a carbamoyl chloride of formula III: **(See formula)** where R1 and R2 have the aforementioned meaning, to obtain a compound of formula I in which R1 represents hydrogen or an alcohol radical, and R1 has the aforementioned meaning; or with an isocyanate of formula IV: **(See formula)** where it has the aforementioned meaning, to obtain a compound of formula I in which R1 represents hydrogen and R2 has the aforementioned meaning. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7213942A FR2180536A1 (en) | 1972-04-20 | 1972-04-20 | 3-carbamoyloxy-5-methyl-1,2-thiazoles - with fungicidal and bactericidal activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES413935A1 true ES413935A1 (en) | 1976-02-01 |
Family
ID=9097214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES413935A Expired ES413935A1 (en) | 1972-04-20 | 1973-04-19 | A procedure for preparation of istitezolic derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4918871A (en) |
| AU (1) | AU5472873A (en) |
| BE (1) | BE798470A (en) |
| DD (2) | DD111782A5 (en) |
| DE (1) | DE2320116A1 (en) |
| ES (1) | ES413935A1 (en) |
| FR (1) | FR2180536A1 (en) |
| HU (1) | HU165992B (en) |
| IL (1) | IL41982A0 (en) |
| IT (1) | IT983012B (en) |
| NL (1) | NL7305437A (en) |
| ZA (1) | ZA732714B (en) |
-
1972
- 1972-04-20 FR FR7213942A patent/FR2180536A1/en active Granted
-
1973
- 1973-04-09 IL IL41982A patent/IL41982A0/en unknown
- 1973-04-18 NL NL7305437A patent/NL7305437A/xx unknown
- 1973-04-19 DD DD178905*A patent/DD111782A5/xx unknown
- 1973-04-19 ES ES413935A patent/ES413935A1/en not_active Expired
- 1973-04-19 DE DE2320116A patent/DE2320116A1/en active Pending
- 1973-04-19 DD DD170305A patent/DD107046A5/xx unknown
- 1973-04-19 HU HURO726A patent/HU165992B/hu unknown
- 1973-04-19 IT IT49556/73A patent/IT983012B/en active
- 1973-04-19 JP JP48043738A patent/JPS4918871A/ja active Pending
- 1973-04-19 BE BE130219A patent/BE798470A/en unknown
- 1973-04-19 AU AU54728/73A patent/AU5472873A/en not_active Expired
- 1973-04-19 ZA ZA732714A patent/ZA732714B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7305437A (en) | 1973-10-23 |
| AU5472873A (en) | 1974-10-24 |
| IL41982A0 (en) | 1973-06-29 |
| IT983012B (en) | 1974-10-31 |
| BE798470A (en) | 1973-10-19 |
| ZA732714B (en) | 1974-06-26 |
| JPS4918871A (en) | 1974-02-19 |
| FR2180536B1 (en) | 1974-07-26 |
| DE2320116A1 (en) | 1973-10-31 |
| DD107046A5 (en) | 1974-07-12 |
| HU165992B (en) | 1974-12-28 |
| DD111782A5 (en) | 1975-03-12 |
| FR2180536A1 (en) | 1973-11-30 |
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