ES411401A1 - A procedure for the obtaining of p-acetamol derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the obtaining of p-acetamol derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES411401A1 ES411401A1 ES411401A ES411401A ES411401A1 ES 411401 A1 ES411401 A1 ES 411401A1 ES 411401 A ES411401 A ES 411401A ES 411401 A ES411401 A ES 411401A ES 411401 A1 ES411401 A1 ES 411401A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- acetamol
- translation
- derivatives
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 206010012335 Dependence Diseases 0.000 abstract 1
- 150000001805 chlorine compounds Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229960003512 nicotinic acid Drugs 0.000 abstract 1
- 239000011664 nicotinic acid Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pyridine Compounds (AREA)
Abstract
A process for obtaining p-acetamol derivatives that respond to the following formula; ** (see formula) ** Where R, is represented by the acid radicals of the following compounds: 4-alpha-isobutyl-phenyl-propionic of the formula ** (see formula) ** Or by, 3-chloro-4-allyloxy-phenylacetic of formula: ** (see formula) ** Or by, the trifluoro-methyl-3-anilino-2-nicotinic acid, of the formula: ** (see formula) ** And by the acid- (trifluoromethyl-2-phenyl) -amino-2-benzoic of formula ** (see formula) ** Essentially characterized in that the reaction is carried out with the acid chlorides described in the presence of bases, such as sodium hydroxide, pyridine, triethylamine and the like, verifying the addiction at room temperature and subsequent heating between 50 and 90º c. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES411401A ES411401A1 (en) | 1973-02-08 | 1973-02-08 | A procedure for the obtaining of p-acetamol derivatives. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES411401A ES411401A1 (en) | 1973-02-08 | 1973-02-08 | A procedure for the obtaining of p-acetamol derivatives. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES411401A1 true ES411401A1 (en) | 1976-01-01 |
Family
ID=8463328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES411401A Expired ES411401A1 (en) | 1973-02-08 | 1973-02-08 | A procedure for the obtaining of p-acetamol derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES411401A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102863350A (en) * | 2011-07-06 | 2013-01-09 | 中国科学院大连化学物理研究所 | Anti-inflammatory analgesia mutual prodrug of non-steroidal antiinflammatory drug and preparation method thereof |
-
1973
- 1973-02-08 ES ES411401A patent/ES411401A1/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102863350A (en) * | 2011-07-06 | 2013-01-09 | 中国科学院大连化学物理研究所 | Anti-inflammatory analgesia mutual prodrug of non-steroidal antiinflammatory drug and preparation method thereof |
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