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ES411189A1 - Procedimiento para la preparacion de eteres heterociclicos. - Google Patents

Procedimiento para la preparacion de eteres heterociclicos.

Info

Publication number
ES411189A1
ES411189A1 ES411189A ES411189A ES411189A1 ES 411189 A1 ES411189 A1 ES 411189A1 ES 411189 A ES411189 A ES 411189A ES 411189 A ES411189 A ES 411189A ES 411189 A1 ES411189 A1 ES 411189A1
Authority
ES
Spain
Prior art keywords
formula
salts
transformed
molecular weight
low molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES411189A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of ES411189A1 publication Critical patent/ES411189A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedimiento para la preparación de éteres heterocíclicos de la fórmula I **fórmula** en la que R1 significa un sistema de anillo heterocíclico, nitrogenado, insaturado y de un único núcleo, que puede contener adicionalmente además un átomo de azufre y/o un anillo bencénico condensado con él, o puede estar sustituido por grupos alcohilo o alcoxi de bajo peso molecular, fenilalcohilo o fenilo, R2 significa un radical fenilo eventualmente sustituido por grupos alcohilo o alcoxi de bajo peso molecular, átomos de cloro o de bromo, que también puede contener en el anillo 1 a 2 átomos de nitrógeno, y A significa un radical alcohileno de cadena recta o ramificada con 2 hasta 6 átomos de carbono, así como sus sales por adición de ácido fisiológicamente compatibles, caracterizado porque se hacen reaccionar compuestos de la fórmula IX R1-O-A-NH-CH2-CH2-NH-R2 (IX) con ésteres de etilenglicol susceptibles de reaccionar y eventualmente se transforman las sales así obtenidas en las bases libres o se transforman las bases en sus sales por adición de ácido.
ES411189A 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos. Expired ES411189A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691946172 DE1946172A1 (de) 1969-09-12 1969-09-12 Neue heterocyclische AEther und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ES411189A1 true ES411189A1 (es) 1975-12-01

Family

ID=5745285

Family Applications (5)

Application Number Title Priority Date Filing Date
ES383564A Expired ES383564A1 (es) 1969-09-12 1970-09-11 Procedimiento para la preparacion de eteres heterociclicos.
ES411186A Expired ES411186A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.
ES411188A Expired ES411188A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.
ES411189A Expired ES411189A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.
ES411187A Expired ES411187A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES383564A Expired ES383564A1 (es) 1969-09-12 1970-09-11 Procedimiento para la preparacion de eteres heterociclicos.
ES411186A Expired ES411186A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.
ES411188A Expired ES411188A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES411187A Expired ES411187A1 (es) 1969-09-12 1973-02-01 Procedimiento para la preparacion de eteres heterociclicos.

Country Status (15)

Country Link
US (1) US3787411A (es)
JP (1) JPS4821949B1 (es)
AT (4) AT308127B (es)
AU (1) AU1977770A (es)
BE (1) BE756127A (es)
BR (1) BR6915366D0 (es)
CA (1) CA925508A (es)
DE (1) DE1946172A1 (es)
ES (5) ES383564A1 (es)
FR (1) FR2070687B1 (es)
GB (1) GB1320395A (es)
IE (1) IE34511B1 (es)
IL (1) IL35297A0 (es)
NL (1) NL7013189A (es)
ZA (1) ZA706140B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954763A (en) * 1972-04-10 1976-05-04 Synthelabo N-Metatrifluoromethylthiophenyl-piperazine
US4136185A (en) * 1972-12-23 1979-01-23 Boehringer Ingelheim Gmbh N-Aryl-N'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof
DE2337461A1 (de) * 1973-07-24 1975-02-06 Boehringer Mannheim Gmbh Neue indolderivate und verfahren zu deren herstellung
JPS5260453U (es) * 1975-10-28 1977-05-02
US4096331A (en) * 1976-12-28 1978-06-20 A. H. Robins Company, Incorporated 1-Substituted-3-aminoethoxypyrrolidines
US4104387A (en) * 1977-05-23 1978-08-01 E. R. Squibb & Sons, Inc. 3-(Arylcycloiminoalkyl)benzisothiazole 1,1-dioxides
DE3005287A1 (de) * 1980-02-13 1981-08-20 Basf Ag, 6700 Ludwigshafen Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel
EP0107293A3 (en) * 1982-09-04 1984-06-06 Pfizer Limited Dihydropyridines
ES2038180T3 (es) * 1986-06-30 1993-07-16 Asahi Kasei Kogyo Kabushiki Kaisha Un procedimiento para preparar un compuesto que es un derivado de pirazina.
FR2658514B1 (fr) * 1990-02-19 1992-06-19 Irceba Nouveaux derives du methyl-4 thiazole, leurs procedes de preparation et les compositions pharmaceutiques en contenant.
CA2090027A1 (en) * 1990-08-31 1992-03-01 Shoichi Chokai Pyrimidine derivatives and drugs
WO1993012792A1 (fr) * 1991-12-20 1993-07-08 Asahi Kasei Kogyo Kabushiki Kaisha Medicament pour les maladies affectant le systeme serotoninergique
DE4425143A1 (de) * 1994-07-15 1996-01-18 Basf Ag Substituierte Pyrimidinverbindungen und deren Verwendung
CN1118454C (zh) * 1994-09-09 2003-08-20 日本新药株式会社 杂环衍生物和医药
DE19728996A1 (de) 1997-07-07 1999-01-14 Basf Ag Triazolverbindungen und deren Verwendung
AU2013259551B2 (en) * 2012-05-09 2017-11-02 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
CN107793362B (zh) * 2016-08-30 2022-04-22 江苏恩华药业股份有限公司 一种苯基哒嗪酮类衍生物的合成及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE612485A (es) * 1961-01-20

Also Published As

Publication number Publication date
US3787411A (en) 1974-01-22
GB1320395A (en) 1973-06-13
CA925508A (en) 1973-05-01
FR2070687B1 (es) 1973-08-10
ES411186A1 (es) 1975-12-01
AT309445B (de) 1973-08-27
NL7013189A (es) 1971-03-16
DE1946172A1 (de) 1971-03-18
JPS4821949B1 (es) 1973-07-02
AU1977770A (en) 1972-03-16
ES411187A1 (es) 1975-12-01
ES383564A1 (es) 1973-06-01
ZA706140B (en) 1971-12-29
ES411188A1 (es) 1975-12-01
BR6915366D0 (pt) 1973-01-25
AT305284B (de) 1973-02-26
IL35297A0 (en) 1970-11-30
AT308126B (de) 1973-06-25
IE34511B1 (en) 1975-05-28
FR2070687A1 (es) 1971-09-17
SU404252A3 (es) 1973-10-26
IE34511L (en) 1971-03-12
AT308127B (de) 1973-06-25
SU404251A3 (es) 1973-10-26
BE756127A (fr) 1971-03-15

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