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ES402115A1 - PROCEDURE FOR OBTAINING IMIDAZO (2,1-A) ISOINDOL DERIVATIVES. - Google Patents

PROCEDURE FOR OBTAINING IMIDAZO (2,1-A) ISOINDOL DERIVATIVES.

Info

Publication number
ES402115A1
ES402115A1 ES402115A ES402115A ES402115A1 ES 402115 A1 ES402115 A1 ES 402115A1 ES 402115 A ES402115 A ES 402115A ES 402115 A ES402115 A ES 402115A ES 402115 A1 ES402115 A1 ES 402115A1
Authority
ES
Spain
Prior art keywords
procedure
formula
approx
acid
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES402115A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES402115A1 publication Critical patent/ES402115A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Indole Compounds (AREA)

Abstract

Procedure for obtaining imidazo [2,1-a] isoindol derivatives of formula I **(See formula)** wherein each of R and R1 signifies a hydrogen, fluorine or chlorine atom, characterized in that a compound of formula VIa or VIb is treated, **(See formula)** wherein R and R1 have the meanings indicated above, in the form of a free base or in the form of an acid addition salt, with water in the presence of an acid, preferably a mineral acid, at a pH of approx. 1 to approx. 4, conveniently at room temperature up to 50ºC. (Machine-translation by Google Translate, not legally binding)
ES402115A 1969-03-05 1972-04-26 PROCEDURE FOR OBTAINING IMIDAZO (2,1-A) ISOINDOL DERIVATIVES. Expired ES402115A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81294869A 1969-03-05 1969-03-05
US82595469A 1969-05-19 1969-05-19
US86517969A 1969-10-09 1969-10-09

Publications (1)

Publication Number Publication Date
ES402115A1 true ES402115A1 (en) 1975-11-01

Family

ID=27420085

Family Applications (3)

Application Number Title Priority Date Filing Date
ES377089A Expired ES377089A1 (en) 1969-03-05 1970-03-03 Imidazoline derivatives
ES402115A Expired ES402115A1 (en) 1969-03-05 1972-04-26 PROCEDURE FOR OBTAINING IMIDAZO (2,1-A) ISOINDOL DERIVATIVES.
ES402117A Expired ES402117A1 (en) 1969-03-05 1972-04-26 Imidazoline derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES377089A Expired ES377089A1 (en) 1969-03-05 1970-03-03 Imidazoline derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES402117A Expired ES402117A1 (en) 1969-03-05 1972-04-26 Imidazoline derivatives

Country Status (8)

Country Link
JP (1) JPS4843120B1 (en)
CA (1) CA939355A (en)
CH (2) CH530980A (en)
DE (1) DE2009780C2 (en)
ES (3) ES377089A1 (en)
FR (2) FR2034663B1 (en)
GB (2) GB1306512A (en)
SE (2) SE365218B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039814A (en) * 1990-05-02 1991-08-13 Merck & Co., Inc. Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl)benzenes
US5310928A (en) * 1991-11-18 1994-05-10 E. I. Du Pont De Nemours And Company Process for preparing biphenyltetrazole compounds
US5206374A (en) * 1991-11-18 1993-04-27 E. I. Du Pont De Nemours And Company Process for preparing tetrazolylphenylboronic acid intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6803799A (en) * 1967-03-23 1968-09-24
US3888846A (en) * 1967-03-30 1975-06-10 Hoffmann La Roche Process for 2(2-(1,3-diazacycloalk-2-enyl))benzophenone derivatives and 1,3-diazacycloalkenyl(2,1-a)isoindole derivatives
US3717658A (en) * 1968-03-07 1973-02-20 Hoffmann La Roche 3'-arylspiro(imidazolidine-2,1'-phthalan)and 2-(2'-(alpha-hydroxy-arylmethyl)-aryl)-2-imidazoline derivatives

Also Published As

Publication number Publication date
ES402117A1 (en) 1975-11-01
GB1306511A (en) 1973-02-14
FR2034663B1 (en) 1974-08-30
FR2034663A1 (en) 1970-12-11
DE2009780C2 (en) 1983-11-24
JPS4843120B1 (en) 1973-12-17
FR2100576A1 (en) 1972-03-24
FR2100576B1 (en) 1975-06-06
GB1306512A (en) 1973-02-14
SE365218B (en) 1974-03-18
SE405249B (en) 1978-11-27
DE2009780A1 (en) 1972-02-17
CH530980A (en) 1972-11-30
ES377089A1 (en) 1972-12-16
CH531511A (en) 1972-12-15
CA939355A (en) 1974-01-01

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