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ES409114A1 - Process for preventing reversion during preparation of nucleus ester salts - Google Patents

Process for preventing reversion during preparation of nucleus ester salts

Info

Publication number
ES409114A1
ES409114A1 ES409114A ES409114A ES409114A1 ES 409114 A1 ES409114 A1 ES 409114A1 ES 409114 A ES409114 A ES 409114A ES 409114 A ES409114 A ES 409114A ES 409114 A1 ES409114 A1 ES 409114A1
Authority
ES
Spain
Prior art keywords
symbols
carbon atoms
hydrogen
iminohalide
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409114A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US203398A external-priority patent/US3868368A/en
Priority claimed from US00203399A external-priority patent/US3845043A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES409114A1 publication Critical patent/ES409114A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A method of preventing the reversal of an iminohalide from a 7-acylamidodeacetoxycephalosporin ester to a 7-acylamidodeacetoxycephalosporin ester during treatment of the iminohalide with an alcohol or thiol, consisting of reacting the iminohalide in an inert organic liquid diluent, in the presence of hydrogen halide, with alcohols or thiols of formulas: ** (See formula) ** where X is oxygen or sulfur; each of the symbols Y and Z represents alkyl such that the alcohol or thiol has approximately 4 to 12 carbon atoms; Y and Z attached to the carbon atom to which they are attached represent a cycloalkyl group of 5 to 8 carbon atoms forming the ring; each of the symbols W and Z1 is hydrogen or C1-C2 alkyl and each of the symbols R1 and R2 is hydrogen or a hydrocarbon radical such that 1,3-diol has from 3 to about 15 carbon atoms; and each of the symbols R3 and R4 is hydrogen or alkyl such that the molecule contains about 2 to 12 carbon atoms. (Machine-translation by Google Translate, not legally binding)
ES409114A 1971-11-30 1972-11-29 Process for preventing reversion during preparation of nucleus ester salts Expired ES409114A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US203398A US3868368A (en) 1971-11-30 1971-11-30 Process for preparing a 7-aminocephalosporin ester
US00203399A US3845043A (en) 1971-11-30 1971-11-30 Preventing reversion during preparation of nucleus ester salts

Publications (1)

Publication Number Publication Date
ES409114A1 true ES409114A1 (en) 1976-04-01

Family

ID=26898573

Family Applications (1)

Application Number Title Priority Date Filing Date
ES409114A Expired ES409114A1 (en) 1971-11-30 1972-11-29 Process for preventing reversion during preparation of nucleus ester salts

Country Status (21)

Country Link
JP (1) JPS5638595B2 (en)
AR (1) AR192529A1 (en)
AT (1) AT324551B (en)
BE (1) BE791925A (en)
BG (2) BG23008A3 (en)
CA (1) CA985672A (en)
CH (1) CH554372A (en)
CS (1) CS188154B2 (en)
DD (1) DD100958A5 (en)
DE (1) DE2258079C3 (en)
ES (1) ES409114A1 (en)
FR (1) FR2163132A5 (en)
GB (1) GB1381339A (en)
HU (1) HU166394B (en)
IE (1) IE36879B1 (en)
IL (1) IL40897A (en)
NL (1) NL173958C (en)
PH (1) PH10235A (en)
PL (1) PL89692B1 (en)
SE (1) SE416400B (en)
YU (1) YU36969B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT378774B (en) * 1982-08-06 1985-09-25 Biochemie Gmbh METHOD FOR DEACYLATING PENICILLINES AND CEPHALOSPORINES
JPS59226670A (en) * 1983-06-03 1984-12-19 Jeol Ltd Transistor inverter

Also Published As

Publication number Publication date
HU166394B (en) 1975-03-28
GB1381339A (en) 1975-01-22
BG22402A3 (en) 1977-02-20
FR2163132A5 (en) 1973-07-20
PL89692B1 (en) 1976-12-31
SE416400B (en) 1980-12-22
JPS4862792A (en) 1973-09-01
PH10235A (en) 1976-10-08
YU36969B (en) 1984-08-31
DE2258079C3 (en) 1980-11-20
AR192529A1 (en) 1973-02-21
NL173958B (en) 1983-11-01
BG23008A3 (en) 1977-05-20
DE2258079B2 (en) 1980-03-27
YU297072A (en) 1982-06-18
DE2258079A1 (en) 1973-06-07
IE36879B1 (en) 1977-03-16
IE36879L (en) 1973-05-30
CH554372A (en) 1974-09-30
IL40897A (en) 1976-06-30
NL173958C (en) 1984-04-02
NL7216158A (en) 1973-06-04
DD100958A5 (en) 1973-10-12
IL40897A0 (en) 1973-01-30
AT324551B (en) 1975-09-10
BE791925A (en) 1973-05-28
CA985672A (en) 1976-03-16
JPS5638595B2 (en) 1981-09-08
CS188154B2 (en) 1979-02-28

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