ES407563A1 - Coating materials for enteric medicaments - Google Patents
Coating materials for enteric medicamentsInfo
- Publication number
- ES407563A1 ES407563A1 ES407563A ES407563A ES407563A1 ES 407563 A1 ES407563 A1 ES 407563A1 ES 407563 A ES407563 A ES 407563A ES 407563 A ES407563 A ES 407563A ES 407563 A1 ES407563 A1 ES 407563A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- alkyl
- see formula
- copolymer
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000463 material Substances 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000001244 carboxylic acid anhydrides Chemical class 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000005250 alkyl acrylate group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 alkylene glycol ether Chemical compound 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000007334 copolymerization reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A procedure for the preparation of a partial ester of alkylene glycol ether and copolymer of C1-C4 alkyl acrylate and unsaturated carboxylic acid anhydride, consisting of the following sequence of reactions: a) Copolymerization of an alkyl acrylate and an unsaturated polybasic carboxylic acid anhydride in a molar ratio of between 1: 5 and 5: 1 to give a copolymer of the formula ** (See formula) ** where R is C1-C4 alkyl R2 is hydrogen or methyl R7 is hydrogen or (see formula) so that they are not the same R3 and R4 are hydrogen or the radical (see formula) where R5 is hydrogen or methyl and R6 is alkyl n2 is 0 or 1. with the proviso that about 10 to 50% of the total potential radicals R3 and R4 is other than hydrogen q is an integer from 1 to 4, n1 is an integer greater than 70 x e and are integers from 1 to 5. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18859171A | 1971-10-12 | 1971-10-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES407563A1 true ES407563A1 (en) | 1976-02-01 |
Family
ID=22693788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES407563A Expired ES407563A1 (en) | 1971-10-12 | 1972-10-11 | Coating materials for enteric medicaments |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS4847590A (en) |
| AR (1) | AR194852A1 (en) |
| AT (2) | AT316139B (en) |
| AU (1) | AU473557B2 (en) |
| BE (1) | BE789919A (en) |
| BR (1) | BR7207119D0 (en) |
| CA (1) | CA1004799A (en) |
| CH (1) | CH575967A5 (en) |
| DD (2) | DD103248A5 (en) |
| DE (1) | DE2250028A1 (en) |
| DK (1) | DK138503B (en) |
| ES (1) | ES407563A1 (en) |
| FR (1) | FR2157847B1 (en) |
| GB (1) | GB1409280A (en) |
| HU (1) | HU165803B (en) |
| IE (1) | IE36731B1 (en) |
| IL (1) | IL40520A (en) |
| IT (1) | IT990509B (en) |
| NL (1) | NL7213765A (en) |
| PH (1) | PH13179A (en) |
| PL (2) | PL102291B1 (en) |
| RO (1) | RO62797A (en) |
| SE (2) | SE400979B (en) |
| YU (1) | YU34904B (en) |
| ZA (1) | ZA727066B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1115596B (en) * | 1978-03-13 | 1986-02-03 | Bayer Italia Spa | METHOD FOR THE PREPARATION OF GASTORESISTANT AND ENTERO-SOLUBLE MICROGRANULES OF PHARMACEUTICAL SUBSTANCES, IN PARTICULAR OF PROTEIN SUBSTANCES AND MICROGRANULES PREPARED WITH THE METHOD |
| GB2164339A (en) * | 1984-09-11 | 1986-03-19 | Ciba Geigy Ag | Polymaleic anhydride derivatives |
| GB2340521B (en) * | 1998-08-15 | 2000-09-13 | Sofitech Nv | Shale-stabilizing additives |
| WO2000069420A1 (en) * | 1999-05-14 | 2000-11-23 | Coraltis Ltd. | Pulse-delivery oral compositions |
| CN113855643B (en) * | 2021-11-10 | 2022-11-11 | 葵花药业集团佳木斯鹿灵制药有限公司 | Mesalazine sustained release preparation for colon-specific drug release and preparation process thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE575343A (en) * | 1955-09-09 | |||
| NL289626A (en) * | 1962-03-06 | 1900-01-01 | ||
| US3369003A (en) * | 1962-03-06 | 1968-02-13 | Sinclair Research Inc | Polymers of tertiary-alkoxyalkyl esters |
| US3387061A (en) * | 1966-05-04 | 1968-06-04 | Union Carbide Corp | Chemical reaction product of polycarboxylic acid and a polymeric polyether |
| GB1213030A (en) * | 1968-08-16 | 1970-11-18 | Daicel Ltd | Process for producing a graft copolymer |
| JPS4931557A (en) * | 1972-07-22 | 1974-03-22 |
-
1972
- 1972-10-03 ZA ZA727066A patent/ZA727066B/en unknown
- 1972-10-04 IE IE1342/72A patent/IE36731B1/en unknown
- 1972-10-05 AU AU47451/72A patent/AU473557B2/en not_active Expired
- 1972-10-06 CA CA153,435A patent/CA1004799A/en not_active Expired
- 1972-10-06 IL IL40520A patent/IL40520A/en unknown
- 1972-10-06 PH PH13985A patent/PH13179A/en unknown
- 1972-10-11 DK DK500572AA patent/DK138503B/en unknown
- 1972-10-11 ES ES407563A patent/ES407563A1/en not_active Expired
- 1972-10-11 HU HUEI436A patent/HU165803B/hu unknown
- 1972-10-11 FR FR7235960A patent/FR2157847B1/fr not_active Expired
- 1972-10-11 SE SE7213104A patent/SE400979B/en unknown
- 1972-10-11 NL NL7213765A patent/NL7213765A/xx not_active Application Discontinuation
- 1972-10-11 BE BE789919D patent/BE789919A/en unknown
- 1972-10-11 GB GB4675772A patent/GB1409280A/en not_active Expired
- 1972-10-11 AR AR244601A patent/AR194852A1/en active
- 1972-10-11 IT IT30357/72A patent/IT990509B/en active
- 1972-10-12 PL PL1972197424A patent/PL102291B1/en unknown
- 1972-10-12 DD DD166198A patent/DD103248A5/xx unknown
- 1972-10-12 BR BR007119/72A patent/BR7207119D0/en unknown
- 1972-10-12 CH CH1490772A patent/CH575967A5/xx not_active IP Right Cessation
- 1972-10-12 JP JP47102327A patent/JPS4847590A/ja active Pending
- 1972-10-12 DE DE2250028A patent/DE2250028A1/en not_active Ceased
- 1972-10-12 RO RO7200072494A patent/RO62797A/en unknown
- 1972-10-12 PL PL1972158236A patent/PL76176B1/xx unknown
- 1972-10-12 AT AT876372A patent/AT316139B/en not_active IP Right Cessation
- 1972-10-12 AT AT858173*7A patent/AT329185B/en active
- 1972-10-12 DD DD176088*A patent/DD109508A5/xx unknown
- 1972-10-12 YU YU2556/72A patent/YU34904B/en unknown
-
1976
- 1976-04-23 SE SE7604731A patent/SE411123B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU165803B (en) | 1974-11-28 |
| DD103248A5 (en) | 1974-01-12 |
| IE36731B1 (en) | 1977-02-02 |
| YU34904B (en) | 1980-04-30 |
| AU4745172A (en) | 1974-04-11 |
| IE36731L (en) | 1973-04-12 |
| RO62797A (en) | 1977-10-15 |
| AU473557B2 (en) | 1976-06-24 |
| DD109508A5 (en) | 1974-11-12 |
| GB1409280A (en) | 1975-10-08 |
| ZA727066B (en) | 1974-05-29 |
| DK138503B (en) | 1978-09-18 |
| AT329185B (en) | 1976-04-26 |
| AR194852A1 (en) | 1973-08-24 |
| PL102291B1 (en) | 1979-03-31 |
| YU255672A (en) | 1979-10-31 |
| IL40520A0 (en) | 1972-12-29 |
| DE2250028A1 (en) | 1973-04-19 |
| AT316139B (en) | 1974-06-25 |
| BR7207119D0 (en) | 1973-07-19 |
| SE400979B (en) | 1978-04-17 |
| IL40520A (en) | 1975-12-31 |
| BE789919A (en) | 1973-04-11 |
| PL76176B1 (en) | 1975-02-28 |
| FR2157847B1 (en) | 1975-10-31 |
| JPS4847590A (en) | 1973-07-06 |
| DK138503C (en) | 1979-02-26 |
| NL7213765A (en) | 1973-04-16 |
| IT990509B (en) | 1975-07-10 |
| FR2157847A1 (en) | 1973-06-08 |
| SE411123B (en) | 1979-12-03 |
| PH13179A (en) | 1980-01-08 |
| CA1004799A (en) | 1977-02-01 |
| SE7604731L (en) | 1976-04-23 |
| ATA858173A (en) | 1975-07-15 |
| CH575967A5 (en) | 1976-05-31 |
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