ES391138A1 - (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia - Google Patents
(cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertoniaInfo
- Publication number
- ES391138A1 ES391138A1 ES391138A ES391138A ES391138A1 ES 391138 A1 ES391138 A1 ES 391138A1 ES 391138 A ES391138 A ES 391138A ES 391138 A ES391138 A ES 391138A ES 391138 A1 ES391138 A1 ES 391138A1
- Authority
- ES
- Spain
- Prior art keywords
- cyano
- hypertonia
- methylphenoxy
- propanes
- coronary disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 (cyano methylphenoxy) hydroxy Chemical group 0.000 title abstract 2
- 206010020852 Hypertonia Diseases 0.000 title abstract 2
- 208000029078 coronary artery disease Diseases 0.000 title 1
- 235000013849 propane Nutrition 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 abstract 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 abstract 1
- 208000001871 Tachycardia Diseases 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 150000003944 halohydrins Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000006794 tachycardia Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
-
- E—FIXED CONSTRUCTIONS
- E05—LOCKS; KEYS; WINDOW OR DOOR FITTINGS; SAFES
- E05D—HINGES OR SUSPENSION DEVICES FOR DOORS, WINDOWS OR WINGS
- E05D15/00—Suspension arrangements for wings
- E05D15/40—Suspension arrangements for wings supported on arms movable in vertical planes
- E05D15/44—Suspension arrangements for wings supported on arms movable in vertical planes with pivoted arms and vertically-sliding guides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1-(2-Cyano-5-methylphenoxy)-2-hydroxy-3-alkylaminopropanes. (I):- (where R is 2-6C alkyl, pref. t. butyl are used for treating coronary conditions, tachycardia and hypertonia. They are prepd. e.g. from an epoxypropane or halohydrin and NH2R or RNHCONHR or by introducing the alkyl into the unsubstd. amine or by removing an easily hydrolysable gp. G from -OCH2 HCH2NHR or by removing protective gp. P from -OCH2 HCH2 R or by hydrolysing an oxazolidinone or by diazotising an 2-aminomethylphenoxy cpd. to the 2-cyano- cpd.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19691950351 DE1950351C3 (en) | 1969-10-06 | 1969-10-06 | 1- (2-Cyano-5-methylphenoxy) -2-hydroxy-3-aIkylaminopropane, process for their preparation and medicaments containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES391138A1 true ES391138A1 (en) | 1973-07-16 |
Family
ID=5747463
Family Applications (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES384244A Expired ES384244A1 (en) | 1969-10-06 | 1970-10-03 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391137A Expired ES391137A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391135A Expired ES391135A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391141A Expired ES391141A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391134A Expired ES391134A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391138A Expired ES391138A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391139A Expired ES391139A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391140A Expired ES391140A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391136A Expired ES391136A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES384244A Expired ES384244A1 (en) | 1969-10-06 | 1970-10-03 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391137A Expired ES391137A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391135A Expired ES391135A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391141A Expired ES391141A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391134A Expired ES391134A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES391139A Expired ES391139A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391140A Expired ES391140A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
| ES391136A Expired ES391136A1 (en) | 1969-10-06 | 1971-05-13 | (cyano methylphenoxy) hydroxy alkylamino - propanes for coronary disease and hypertonia |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS501262B1 (en) |
| AT (10) | AT306699B (en) |
| BG (8) | BG17528A3 (en) |
| CH (1) | CH542814A (en) |
| CS (1) | CS162731B2 (en) |
| DE (1) | DE1950351C3 (en) |
| DK (1) | DK128237B (en) |
| ES (9) | ES384244A1 (en) |
| PL (3) | PL84642B1 (en) |
| RO (9) | RO58533A (en) |
| SE (1) | SE375094B (en) |
| SU (6) | SU423291A3 (en) |
| YU (1) | YU34516B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101950B1 (en) | 1996-12-12 | 1998-09-30 | Uponor Bv | Method and apparatus for utilizing a recyclable plastic material and a plastic product manufactured by a press device |
| RU2660811C1 (en) * | 2017-03-21 | 2018-07-10 | Общество с ограниченной ответственностью Научно-производственное предприятие "Резонанс" (ООО НПП "Резонанс") | Induction electrical machine |
-
1969
- 1969-10-02 BG BG018263A patent/BG17528A3/en unknown
- 1969-10-06 DE DE19691950351 patent/DE1950351C3/en not_active Expired
-
1970
- 1970-09-23 CS CS646770A patent/CS162731B2/cs unknown
- 1970-10-02 BG BG015776A patent/BG17293A3/en unknown
- 1970-10-02 CH CH1461770A patent/CH542814A/en not_active IP Right Cessation
- 1970-10-02 BG BG018261A patent/BG17527A3/en unknown
- 1970-10-02 BG BG018262A patent/BG17294A3/en unknown
- 1970-10-02 BG BG018268A patent/BG17531A3/en unknown
- 1970-10-02 BG BG018265A patent/BG17296A3/en unknown
- 1970-10-02 BG BG018264A patent/BG17295A3/en unknown
- 1970-10-02 BG BG018266A patent/BG17529A3/en unknown
- 1970-10-03 ES ES384244A patent/ES384244A1/en not_active Expired
- 1970-10-05 SE SE1347570A patent/SE375094B/xx unknown
- 1970-10-05 SU SU1705732A patent/SU423291A3/ru active
- 1970-10-05 PL PL17334270A patent/PL84642B1/en unknown
- 1970-10-05 PL PL14378570A patent/PL84252B1/en unknown
- 1970-10-05 DK DK505570A patent/DK128237B/en not_active IP Right Cessation
- 1970-10-05 YU YU244470A patent/YU34516B/en unknown
- 1970-10-05 SU SU1705731A patent/SU422137A3/en active
- 1970-10-05 PL PL17334370A patent/PL84637B1/en unknown
- 1970-10-05 JP JP8675670A patent/JPS501262B1/ja active Pending
- 1970-10-05 SU SU1705733A patent/SU421182A3/en active
- 1970-10-05 SU SU1705730A patent/SU417938A3/en active
- 1970-10-05 SU SU1699774A patent/SU426360A3/en active
- 1970-10-06 AT AT1052971A patent/AT306699B/en not_active IP Right Cessation
- 1970-10-06 AT AT1053171A patent/AT306701B/en not_active IP Right Cessation
- 1970-10-06 RO RO6727070A patent/RO58533A/ro unknown
- 1970-10-06 RO RO6727170A patent/RO59186A/ro unknown
- 1970-10-06 AT AT1052871A patent/AT306698B/en not_active IP Right Cessation
- 1970-10-06 RO RO6461670A patent/RO56983A/ro unknown
- 1970-10-06 RO RO6726870A patent/RO58532A/ro unknown
- 1970-10-06 RO RO6727370A patent/RO58548A/ro unknown
- 1970-10-06 AT AT1052671A patent/AT306696B/en not_active IP Right Cessation
- 1970-10-06 RO RO6727270A patent/RO58534A/ro unknown
- 1970-10-06 AT AT900970A patent/AT302274B/en not_active IP Right Cessation
- 1970-10-06 AT AT1052471A patent/AT306694B/en not_active IP Right Cessation
- 1970-10-06 AT AT1052771A patent/AT306697B/en not_active IP Right Cessation
- 1970-10-06 AT AT1052371A patent/AT308072B/en not_active IP Right Cessation
- 1970-10-06 AT AT1053071A patent/AT306700B/en not_active IP Right Cessation
- 1970-10-06 RO RO6728970A patent/RO58550A/ro unknown
- 1970-10-06 RO RO6727470A patent/RO58549A/ro unknown
- 1970-10-06 RO RO6726970A patent/RO59185A/ro unknown
- 1970-10-06 AT AT1052571A patent/AT306695B/en not_active IP Right Cessation
-
1971
- 1971-05-13 ES ES391137A patent/ES391137A1/en not_active Expired
- 1971-05-13 ES ES391135A patent/ES391135A1/en not_active Expired
- 1971-05-13 ES ES391141A patent/ES391141A1/en not_active Expired
- 1971-05-13 ES ES391134A patent/ES391134A1/en not_active Expired
- 1971-05-13 ES ES391138A patent/ES391138A1/en not_active Expired
- 1971-05-13 ES ES391139A patent/ES391139A1/en not_active Expired
- 1971-05-13 ES ES391140A patent/ES391140A1/en not_active Expired
- 1971-05-13 ES ES391136A patent/ES391136A1/en not_active Expired
- 1971-09-21 SU SU1699773A patent/SU503507A3/en active
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