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ER Squibb and Sons LLC
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ER Squibb and Sons LLC
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Application filed by ER Squibb and Sons LLCfiledCriticalER Squibb and Sons LLC
Publication of ES384127A1publicationCriticalpatent/ES384127A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
A method for obtaining a tetracycline antibiotic free from colored impurities comprising contacting an antibiotic solution containing colored impurities at a ph of from about 0.5 to about 4.5 with from about 0.5 to about 4, 5 liters of an organic base per kg of tetracycline antibiotic activity in the solution, and crystallize the resulting mixture to obtain a tetracycline antibiotic free of colored impurities. (Machine-translation by Google Translate, not legally binding)
ES384127A1969-10-011970-09-30A procedure for obtaining a tetracycline antibiotic. (Machine-translation by Google Translate, not legally binding)
ExpiredES384127A1
(en)
Procedure for the monohydration of the equimolecular complex formed by ascorbic acid and pyridoxine. (Machine-translation by Google Translate, not legally binding)