ES336470A1 - Methylalkanoyloxymethyl ketals of prednisolone derivatives - Google Patents
Methylalkanoyloxymethyl ketals of prednisolone derivativesInfo
- Publication number
- ES336470A1 ES336470A1 ES336470A ES336470A ES336470A1 ES 336470 A1 ES336470 A1 ES 336470A1 ES 336470 A ES336470 A ES 336470A ES 336470 A ES336470 A ES 336470A ES 336470 A1 ES336470 A1 ES 336470A1
- Authority
- ES
- Spain
- Prior art keywords
- methylalkanoyloxymethyl
- ketals
- prednisolone derivatives
- compounds
- prednisolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises compounds of formula <FORM:1120337/C2/1> wherein R is an alkyl group having 3-5 carbon atoms and X is a hydrogen or fluorine atom, and their preparation by reaction of the corresponding 16a ,17a -diol with the appropriate alkanoyloxy-acetone. Pharmaceutical compositions.-The compounds of the invention have anti-inflammatory activity and may be used in ointments, creams, gels, tablets, and spirit solutions.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1048/66A SE307576B (en) | 1966-01-27 | 1966-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES336470A1 true ES336470A1 (en) | 1970-04-01 |
Family
ID=20257516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES336470A Expired ES336470A1 (en) | 1966-01-27 | 1967-01-24 | Methylalkanoyloxymethyl ketals of prednisolone derivatives |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3524850A (en) |
| AT (1) | AT269385B (en) |
| BE (1) | BE692983A (en) |
| CH (1) | CH487872A (en) |
| DE (1) | DE1618028A1 (en) |
| ES (1) | ES336470A1 (en) |
| FR (1) | FR6257M (en) |
| GB (1) | GB1120337A (en) |
| GR (1) | GR33327B (en) |
| NL (1) | NL6700465A (en) |
| SE (1) | SE307576B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2278122C1 (en) * | 2004-12-27 | 2006-06-20 | Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) | 9α-FLUORO-16α-HYDROXYPREDNISOLON [3H]-ACETONIDE HIGHLY LABELED WITH TRITIUM |
| UA108858C2 (en) | 2009-09-11 | 2015-06-25 | ISOXALIDINE DERIVATIVES |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3048581A (en) * | 1960-04-25 | 1962-08-07 | Olin Mathieson | Acetals and ketals of 16, 17-dihydroxy steroids |
| US3341526A (en) * | 1965-01-12 | 1967-09-12 | Bofors Ab | Acyloxyacetals of fluoro-16alpha-hydroxyprednisolones |
-
1966
- 1966-01-27 SE SE1048/66A patent/SE307576B/xx unknown
-
1967
- 1967-01-05 DE DE19671618028 patent/DE1618028A1/en active Pending
- 1967-01-12 NL NL6700465A patent/NL6700465A/xx unknown
- 1967-01-18 US US610010A patent/US3524850A/en not_active Expired - Lifetime
- 1967-01-19 AT AT52967A patent/AT269385B/en active
- 1967-01-20 BE BE692983D patent/BE692983A/xx unknown
- 1967-01-24 ES ES336470A patent/ES336470A1/en not_active Expired
- 1967-01-24 CH CH101267A patent/CH487872A/en not_active IP Right Cessation
- 1967-01-25 GR GR670133327A patent/GR33327B/en unknown
- 1967-01-26 FR FR92659A patent/FR6257M/fr not_active Expired
- 1967-01-26 GB GB3976/67A patent/GB1120337A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6700465A (en) | 1967-07-28 |
| CH487872A (en) | 1970-03-31 |
| GR33327B (en) | 1967-11-23 |
| SE307576B (en) | 1969-01-13 |
| US3524850A (en) | 1970-08-18 |
| FR6257M (en) | 1968-08-19 |
| DE1618028A1 (en) | 1970-10-29 |
| AT269385B (en) | 1969-03-10 |
| GB1120337A (en) | 1968-07-17 |
| BE692983A (en) | 1967-07-03 |
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