[go: up one dir, main page]

ES2136535B1 - SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42. - Google Patents

SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42.

Info

Publication number
ES2136535B1
ES2136535B1 ES9700794A ES9700794A ES2136535B1 ES 2136535 B1 ES2136535 B1 ES 2136535B1 ES 9700794 A ES9700794 A ES 9700794A ES 9700794 A ES9700794 A ES 9700794A ES 2136535 B1 ES2136535 B1 ES 2136535B1
Authority
ES
Spain
Prior art keywords
peptide
production
antibodies against
beta amyloid
synthetic peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9700794A
Other languages
Spanish (es)
Other versions
ES2136535A1 (en
Inventor
Enrique Mendez
Adolfo Jimenez
Patricia Alfonso
Juan Solis
Pablo Albar
Jorge Ghiso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES9700794A priority Critical patent/ES2136535B1/en
Publication of ES2136535A1 publication Critical patent/ES2136535A1/en
Application granted granted Critical
Publication of ES2136535B1 publication Critical patent/ES2136535B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Peptides Or Proteins (AREA)

Abstract

Péptido sintético para la producción de anticuerpos contra el péptido beta amiloide 1-42. Los anticuerpos mono y policlonales generados para el reconocimiento específico de ambas formas del Ab son escasos pero representan una herramienta de gran utilidad potencial para el diagnóstico y el estudio molecular de la enfermedad de Alzheimer. En la presente invención se emplea como imnunógeno un nuevo péptido sintético (péptido Ab37-42). Este péptido permite la elaboración de un producto para el diagnóstico de las amiloidosis y para el estudio de su patogenia.Synthetic peptide for the production of antibodies against beta amyloid peptide 1-42. Mono and polyclonal antibodies generated for the specific recognition of both forms of Ab are scarce but represent a tool of great potential utility for the diagnosis and molecular study of Alzheimer's disease. In the present invention, a new synthetic peptide (peptide Ab37-42) is used as an immunogen. This peptide allows the elaboration of a product for the diagnosis of amyloidosis and for the study of its pathogenesis.

ES9700794A 1997-04-15 1997-04-15 SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42. Expired - Fee Related ES2136535B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9700794A ES2136535B1 (en) 1997-04-15 1997-04-15 SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9700794A ES2136535B1 (en) 1997-04-15 1997-04-15 SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42.

Publications (2)

Publication Number Publication Date
ES2136535A1 ES2136535A1 (en) 1999-11-16
ES2136535B1 true ES2136535B1 (en) 2000-08-16

Family

ID=8298955

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9700794A Expired - Fee Related ES2136535B1 (en) 1997-04-15 1997-04-15 SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42.

Country Status (1)

Country Link
ES (1) ES2136535B1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
ES2136535A1 (en) 1999-11-16

Similar Documents

Publication Publication Date Title
ATE217883T1 (en) PENTAPEPTIDE AMIDES AND ESTERS THAT INHIBIT HUMAN CANCER
UY27062A1 (en) HUMANIZED ANTIBODIES RECOGNIZING THE BETA AMYLOID PEPTIDE
ATE355293T1 (en) SUBSTITUTED 7-AZA-(2.2.1)BICYCLOHEPTANES FOR THE TREATMENT OF DISEASES
UY28337A1 (en) HUMANIZED ANTIBODIES RECOGNIZING THE BETA AMILOID PEPTIDE
NO965378D0 (en) Pyrazolo and pyrolopyridines
ATE507839T1 (en) COMBINATION THERAPY
ES2091684T3 (en) THERAPEUTIC APPLICATION OF CHEMICAL AND RADIO-MARKED ANTIBODIES AGAINST THE RESTRICTED DIFFERENTIATION ANTIGEN OF HUMAN B-LYMPHOCYTES FOR THE TREATMENT OF B-CELL LYMPHOMA.
UY27721A1 (en) HUMANIZED ANTIBODIES RECOGNIZING THE BETA AMYLOID PEPTIDE.
ATE258379T1 (en) NUCLEIC ACID CODING FOR A TUMOR REJECTION ANTIGEN PRECURSOR
AR001413A1 (en) Tricyclic carbamate compounds, useful for the inhibition of protein g function and for the treatment of proliferative diseases.
ES2168254T3 (en) NEW 7-SUBSTITUTES-9- (AMINO SUBSTITUTED) -6-DESMETIL-6-DEOXITETRACICLINES.
UY28514A1 (en) NEW COMPOUNDS
MX9301129A (en) NEW CYCLOSPORINS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
ES2113891T3 (en) MONOCLONAL MOUSE ANTIBODIES.
ATE502642T1 (en) COMBINATIONS FOR THE TREATMENT OF IMMUNO-INFLAMMATORY DISEASES
DE69608773D1 (en) Steel for the manufacture of divisible machine parts and machine parts made from this steel
PA8527401A1 (en) 7-OXO-PYRIDOPIRIMIDINAS (II)
ATE159300T1 (en) MONOCLONAL ANTIBODIES AGAINST HUMAN IGE
ES2165506T3 (en) ANTAGONISTS OF IL-8 FOR THE TREATMENT OF ASTHMA.
DK0804465T3 (en) New elastase inhibitors
ES2183923T3 (en) CHROMONE DERIVATIVES
ES2136535B1 (en) SYNTHETIC PEPTIDE FOR THE PRODUCTION OF ANTIBODIES AGAINST THE BETA AMYLOID PEPTIDE 1-42.
ES2074137T3 (en) USE OF FLUOROCHEMICAL PRODUCTS IN LEATHER MANUFACTURE.
DE69912621D1 (en) LIPSTICK AND ITS PRODUCTION PROCESS
DE59001779D1 (en) JEWELRY STONE COMPOSITE AND METHOD FOR THE PRODUCTION THEREOF.

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19991116

Kind code of ref document: A1

Effective date: 19991116

FD2A Announcement of lapse in spain

Effective date: 20110819